Patents by Inventor Sean Konrad McHugh

Sean Konrad McHugh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HSP90-inhibiting zearalanol compounds and methods of producing and using same
    Patent number: 7553979
    Abstract: Zearalanol compounds are described and demonstrated or predicted to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents in the treatment and prevention of various disorders. Methods of synthesis and use of such compounds are also described and claimed.
    Type: Grant
    Filed: November 8, 2002
    Date of Patent: June 30, 2009
    Assignee: Conforma Therapeutics Corporation
    Inventors: Srinivas R. Kasibhatla, Jean-Yves Le Brazidec, Sean Konrad McHugh, Marcus F. Boehm
  • Ansamycins having improved pharmacological and biological properties
    Patent number: 7465718
    Abstract: Ansamycins and methods of preparing and using the same are described. At least some of these ansamycins exhibit one or more of improved aqueous formulation ability, chemical stability, and bioavailability. Some of the derivatives described are dimers. These and others described can include one or more solubilizing groups that have expected merit in rendering the overall compounds useful as drugs and prodrugs.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: December 16, 2008
    Assignee: Conforma Therapeutics Corporation
    Inventors: Lin Zhang, Jean-Yves Le Brazidec, Lawrence C. Fritz, Francis J. Burrows, Marcus F. Boehm, Junhua Fan, Sean Konrad McHugh