Patents by Inventor Sean M. MADDOX

Sean M. MADDOX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Atropisomerism for enhanced kinase inhibitor selectivity
    Patent number: 10934300
    Abstract: The invention provides a series of conformationally stable and selective kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds. The compounds herein are atropisomers having increased kinase selectivity, and are for use in treating conditions that benefit from selective kinase inhibition.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: March 2, 2021
    Assignee: San Diego State University (SDSU) Foundation
    Inventors: Jeffrey L. Gustafson, Sean T. Toenjes, Sean M. Maddox
  • ATROPISOMERISM FOR ENHANCED KINASE INHIBITOR SELECTIVITY
    Publication number: 20200165258
    Abstract: The invention provides a series of conformationally stable and selective kinase inhibitors, and methods of using the kinase inhibitors. The effect of atropisomerism on kinase selectivity was assessed, finding improved selectivity compared to rapidly interconverting parent compounds. The compounds herein are atropisomers having increased kinase selectivity, and are for use in treating conditions that benefit from selective kinase inhibition.
    Type: Application
    Filed: June 21, 2018
    Publication date: May 28, 2020
    Applicant: San Diego State University Research Foundation
    Inventors: Jeffrey L. GUSTAFSON, Sean T. TOENJES, Sean M. MADDOX