Patents by Inventor Sean M. O'Connor
Sean M. O'Connor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12201809Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.Type: GrantFiled: July 28, 2021Date of Patent: January 21, 2025Assignee: AMGEN INC.Inventors: Scott R. Gibson, Sheldon B. Moberg, Basel Hasan Taha, Margaux Frances Boyaval, Mark A. Destefano, Lawton Laurence, John C. Love, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente, Antonio Ubach, Rajan Ramaswamy, Daniel S. Codd, Scott Beaver, Kevin L. Bokelman, Ian P. Dardani, Sean M. O'connor, Danielle Feldman
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Patent number: 11907070Abstract: An integrated circuit includes one or more processing units that execute instructions that employ a register file, control logic creates a pre-startup register free list, prior to normal operation of at least one of the processing units, that includes a list of registers devoid of defective registers. In some implementations, no column and row repair information is provided to register file repair logic. In certain examples, the register file is configured as a repair-less register file. During normal operation of the one or more processing units, the integrated circuit employs the pre-startup register free list to select registers in a register file for the executing instructions. Associated methods are also presented.Type: GrantFiled: July 30, 2021Date of Patent: February 20, 2024Assignee: ADVANCED MICRO DEVICES, INC.Inventors: Eric Busta, Michael L. Golden, Sean M. O′Mullan, James Wingfield, Keith A. Kasprak, Russell Schreiber, Michael Estlick
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Patent number: 11885228Abstract: A system and method for inspecting fan blade clearances in a fan stator module are presented. The method includes rotating a fan rotor assembly that includes an attached bracket situated between adjacent fan blades connected to the fan rotor assembly. The bracket includes a laser module and an inclinometer configured to measure a circumferential position of the laser module. The method further includes projecting a laser beam from the laser module to the fan case to determine a distance measurement between the laser module and the fan case at multiple circumferential points around the fan case. The distance measurement and circumferential position data is processed by a computing device to determine a clearance distance between a fan blade and the fan case.Type: GrantFiled: February 9, 2022Date of Patent: January 30, 2024Assignee: General Electric CompanyInventors: Subramanya Shankar, Marc Christopfel, Brian G. Quinn, Omar A. Ramirez, Sean M. O′Melia
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Patent number: 11795991Abstract: A compensating fastener assembly is configured to secure a fastener to a surface element. The compensating fastener assembly includes a compression limiter having a cylindrical main body and a flange, the cylindrical main body defining a channel and a longitudinal axis. The compensating fastener assembly further includes a spring defining a central passage. The central passage of the spring is configured to receive the main body of the compression limiter such that a first end of the spring is configured to be disposed adjacent the flange of the compression limiter.Type: GrantFiled: June 29, 2021Date of Patent: October 24, 2023Assignee: Illinois Tool Works Inc.Inventors: Chad Michael Clark, Ronald C. Owens, II, Jason Paradis, Sean M. O'Reilly
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Publication number: 20230250730Abstract: A system and method for inspecting fan blade clearances in a fan stator module are presented. The method includes rotating a fan rotor assembly that includes an attached bracket situated between adjacent fan blades connected to the fan rotor assembly. The bracket includes a laser module and an inclinometer configured to measure a circumferential position of the laser module. The method further includes projecting a laser beam from the laser module to the fan case to determine a distance measurement between the laser module and the fan case at multiple circumferential points around the fan case. The distance measurement and circumferential position data is processed by a computing device to determine a clearance distance between a fan blade and the fan case.Type: ApplicationFiled: February 9, 2022Publication date: August 10, 2023Applicant: General Electric CompanyInventors: Subramanya Shankar, Marc Christopfel, Brian G. Quinn, Omar A. Ramirez, Sean M. O'Melia
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Publication number: 20230032375Abstract: An integrated circuit includes one or more processing units that execute instructions that employ a register file, control logic creates a pre-startup register free list, prior to normal operation of at least one of the processing units, that includes a list of registers devoid of undefective registers. In some implementations, no column and row repair information is provided to register file repair logic. In certain examples, the register file is configured as a repair-less register file. During normal operation of the one or more processing units, the integrated circuit employs the pre-startup register free list to select registers in a register file for the executing instructions. Associated methods are also presented.Type: ApplicationFiled: July 30, 2021Publication date: February 2, 2023Inventors: Eric Busta, Michael L. Golden, Sean M. O'Mullan, James Wingfield, Keith A. Kasprak, Russell Schreiber, Michael Estlick
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Publication number: 20230019172Abstract: A user-initiated fluid pathway connection includes: a connection hub, a piercing member, a sterile sleeve, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the piercing member is initially retained within the sterile sleeve between the connection hub and the pierceable seal of the drug container. The connection hub may include an internal aperture within the connection hub which functions as a flow restrictor and wherein a piercing member is connected to one end of the internal aperture and a fluid conduit is connected to another end of the internal aperture. A drug delivery pump with integrated sterility maintenance features includes a housing, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection as described above, a power and control system, and a drive mechanism connected to a drug container are mounted. Methods of assembly and operation are also provided.Type: ApplicationFiled: September 27, 2022Publication date: January 19, 2023Inventors: Sean M. O'Connor, Ian B. Hanson, Paul F. Bente, IV, Rajan Ramaswamy, Daniel S. Codd, Scott W. Beaver, Kevin L. Bokelman, John C. Love
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Publication number: 20220397610Abstract: An energy storage system can comprise a stack of multiple battery modules, a plurality of ultrasound emitter transducers, a plurality of ultrasound receiving transducers, one or more excitation modules, one or more capture modules, and an ultrasound battery management system. Each ultrasound emitter transducer and each ultrasound receiving transducer can be acoustically coupled to a surface of a respective one of the battery modules. The excitation module(s) can be electrically interfaced with the plurality of ultrasound emitter transducers, and the capture module(s) can be electrically interface with the plurality of ultrasound receiving transducers. The ultrasound battery management system controller can be configured to initiate battery module ultrasound interrogation sequences.Type: ApplicationFiled: June 14, 2022Publication date: December 15, 2022Inventors: Maura C. APPLEBERRY, Thomas C. FERREE, Paul A. PAQUETTE, Sean M. O'DAY, Shawn D. MURPHY, Jeffrey A. KOWALSKI
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Patent number: 11484644Abstract: A user-initiated fluid pathway connection includes: a connection hub, a piercing member, a sterile sleeve, and a drug container having a cap, a pierceable seal, a barrel, and a plunger seal, wherein the piercing member is initially retained within the sterile sleeve between the connection hub and the pierceable seal of the drug container. The connection hub may include an internal aperture within the connection hub which functions as a flow restrictor and wherein a piercing member is connected to one end of the internal aperture and a fluid conduit is connected to another end of the internal aperture. A drug delivery pump with integrated sterility maintenance features includes a housing, upon which an activation mechanism, an insertion mechanism, a fluid pathway connection as described above, a power and control system, and a drive mechanism connected to a drug container are mounted. Methods of assembly and operation are also provided.Type: GrantFiled: August 5, 2019Date of Patent: November 1, 2022Inventors: Sean M. O'Connor, Ian B. Hanson, Paul F. Bente, IV, Rajan Ramaswamy, Daniel S. Codd, Scott W. Beaver, Kevin Bokelman, John C. Love
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Publication number: 20220265898Abstract: The described invention provides soft tissue grafts, hard tissue grafts, and composite soft/hard tissue grafts and methods of producing such grafts. The grafts comprise a three-dimensional carrier matrix, a growth factor composition comprising an autologous platelet-rich fibrin and a cell culture composition comprising a culture medium, a population of cells suspended in the culture medium, and cells impregnated on or in a surface of osteoconductive particles.Type: ApplicationFiled: May 3, 2022Publication date: August 25, 2022Inventors: Nicholas Elian, Sean M. O'Connell, William K. Boss, Jr.
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Publication number: 20220218900Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.Type: ApplicationFiled: March 7, 2022Publication date: July 14, 2022Inventors: Scott R. Gibson, Sheldon B, Moberg, Basel Hasan Taha, Margaux Frances Boyaval, Mark A. Destefano, John C. Love, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente, Rajan Ramaswamy, Daniel S. Codd, Scott Beaver, Kevin L. Bokelman, Sean M. O'connor, Robert Decker, Gautam N. Shetty, Ryan M. Agard, Nicholas J. Ciccarelli, Daniel Davenport
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Patent number: 11364323Abstract: The described invention provides soft tissue grafts, hard tissue grafts, and composite soft/hard tissue grafts and methods of producing such grafts. The grafts comprise a three-dimensional carrier matrix, a growth factor composition comprising an autologous platelet-rich fibrin and a cell culture composition comprising a culture medium, a population of cells suspended in the culture medium, and cells impregnated on or in a surface of osteoconductive particles.Type: GrantFiled: September 11, 2019Date of Patent: June 21, 2022Assignee: REJUVABLAST LLCInventors: Nicholas Elian, Sean M. O'Connell, William K. Boss, Jr.
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Patent number: 11266777Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.Type: GrantFiled: February 13, 2017Date of Patent: March 8, 2022Assignee: AMGEN INC.Inventors: Scott R. Gibson, Sheldon B. Moberg, Basel Hasan Taha, Margaux Frances Boyaval, Mark A. Destefano, John C. Love, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente, Rajan Ramaswamy, Daniel S. Codd, Scott Beaver, Kevin L. Bokelman, Sean M. O'connor, Robert Decker, Gautam N. Shetty, Ryan M. Agard, Nicholas J. Ciccarelli, Daniel Davenport
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Publication number: 20220003264Abstract: A compensating fastener assembly is configured to secure a fastener to a surface element. The compensating fastener assembly includes a compression limiter having a cylindrical main body and a flange, the cylindrical main body defining a channel and a longitudinal axis. The compensating fastener assembly further includes a spring defining a central passage. The central passage of the spring is configured to receive the main body of the compression limiter such that a first end of the spring is configured to be disposed adjacent the flange of the compression limiter.Type: ApplicationFiled: June 29, 2021Publication date: January 6, 2022Inventors: Chad Michael Clark, Ronald C. Owens, II, Jason Paradis, Sean M. O'Reilly
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Publication number: 20210402083Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.Type: ApplicationFiled: July 28, 2021Publication date: December 30, 2021Inventors: Scott R. Gibson, Sheldon B. Moberg, Basel Hasan Taha, Margaux Frances Boyaval, Mark A. Destefano, Lawton Laurence, John C. Love, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente, Antonio Ubach, Rajan Ramaswamy, Daniel S. Codd, Scott Beaver, Kevin L. Bokelman, Ian P. Dardani, Sean M. O'connor, Danielle Feldman
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Patent number: 11173244Abstract: A drive mechanism includes a housing, a piston adapted to impart movement to a plunger seal within a drug container, a plurality of biasing members disposed in parallel, and a retainer. The biasing members are disposed to release energy to cause movement of the piston from a retracted first position to the extended second position, the piston bearing against the plunger seal to dispense medicine. The retainer is disposed to maintain the biasing members in the energized position and to release the biasing members to permit the piston to dispense the medicine. The drive mechanism may also include an end-of-dose indicator to identify at least one of when the sleeve assembly is disposed subjacent a window in the housing, the relative motion of the sleeve assembly with reference to the window or another reference component, the stoppage of such motion, and the rated or change of rate of motion.Type: GrantFiled: May 8, 2019Date of Patent: November 16, 2021Assignee: UNL Holdings LLCInventors: Ryan M. Agard, Ian B. Hanson, Nicholas J. Ciccarelli, Sean M. O'Connor, Kevin Bokelman, Paul F. Bente, IV
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Patent number: 11129936Abstract: Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device includes a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector defines a sterile fluid flowpath between the container and the insertion mechanism. A cannula initially disposed about the needle is included.Type: GrantFiled: April 7, 2017Date of Patent: September 28, 2021Assignee: AMGEN INC.Inventors: Scott R. Gibson, Sheldon B. Moberg, Basel Hasan Taha, Margaux Frances Boyaval, Mark A. Destefano, Lawton Laurence, John C. Love, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente, Antonio Ubach, Rajan Ramaswamy, Daniel S. Codd, Scott Beaver, Kevin L. Bokelman, Ian P. Dardani, Sean M. O'connor, Danielle Feldman
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Patent number: 11033679Abstract: A fluid pathway assembly includes a needle insertion mechanism, a fluid conduit, and a fluid pathway connection. The fluid pathway assembly may further include a drug container to hold a drug fluid prior to initiation of the injection. The assembly may include a carrier disposed along at least a portion of the fluid pathway assembly, and/or a drug container. The fill-finish cartridge functions to retain the components of the fluid pathway assembly in a sterile condition, while allowing for easy integration of the fluid pathway assembly and the drug container into a standard fill-finish process. Methods of constructing a cartridge, filling a drug container included in a cartridge, and incorporating the same into a drug delivery device are disclosed.Type: GrantFiled: March 12, 2013Date of Patent: June 15, 2021Assignee: UNL HOLDINGS LLCInventors: Ian B. Hanson, Paul F. Bente, IV, Sean M. O'Connor, Matthew J. Clemente, Ryan M. Agard, Nicholas J. Ciccarelli
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Patent number: 10933189Abstract: A variable rate controlled delivery drive mechanism includes a drive mechanism housing, at least partially within which initially resides a biasing member positioned in an initially energized state within an inner cavity of a piston. The drive mechanism may include a gear drive having one or more screws and one or more corresponding nuts. The piston contacts a plunger seal and is configured to axially translate the plunger seal, by force asserted upon it from the biasing member, from a first position to a second position within a drug container for drug delivery. The biasing member is metered from free expansion from its energized state by the gear drive and a gear assembly mechanism having a motor. A drug delivery pump utilizes such variable rate controlled delivery mechanisms. A status reader configured to recognize one or more corresponding status triggers is utilized to provide feedback to a user.Type: GrantFiled: May 23, 2018Date of Patent: March 2, 2021Assignee: UNL Holdings LLCInventors: Paul F. Bente, IV, Ian B. Hanson, Vincent E. Mandes, Sean M. O'Connor
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Publication number: 20210046244Abstract: A replaceable fluid restriction mechanism 500, 1500 includes: an aperture 520A residing adjacent to a fluid pathway connection and configured to permit flow of a drug fluid through the aperture 520A when the fluid pathway connection is open; an entry point 520B of a fluid channel 520C configured such that the flow of drug fluid can travel through aperture 520A to the entry point 520B and through the fluid channel 520C to an exit point 520D; and an outlet aperture 514 of a port 512 through which the flow of drug fluid may travel after exiting the exit point 520D, wherein a fluid conduit 30 is connected to the fluid restriction mechanism at the outlet aperture. A configurable fluid restriction mechanism 500, 1500 includes a plurality of fluid channels 520C, 521C, 522C, 523C, selectable to align with the entry point 520B and an exit point 520D of the fluid restriction mechanism.Type: ApplicationFiled: March 24, 2020Publication date: February 18, 2021Inventors: Sean M. O'Connor, Ian B. Hanson, Paul F. Bente, IV, Matthew J. Clemente