Abstract: Mice are provided that comprise a reduction or deletion of ADAM6 activity from an endogenous ADAM6 locus, or that lack an endogenous locus encoding a mouse ADAM6 protein, wherein the mice comprise a sequence encoding an ADAM6 or ortholog or homolog or fragment thereof that is functional in a male mouse. In one embodiment, the sequence is an ectopic ADAM6 sequence or a sequence that confers upon a male mouse the ability to generate offspring by mating. Mice and cells with genetically modified immunoglobulin heavy chain loci that comprise an ectopic nucleotide sequence encoding a mouse ADAM6 or functional fragment or homolog or ortholog thereof are also provided.

Abstract: Methods and apparatus for generating, distributing, and/or presenting social networking content in conjunction with video content are described. In accordance with various embodiments, social networking related information, e.g., comments, remarks and/or a twitter feed, are displayed in conjunction with the display of video to which the social networking information relates. The social networking related information may be displayed on the same or a different device from that which is used to display the video comments. In some embodiments, the social networking information, e.g., comments on a program, event or broadcast, are displayed on a personal computer or other device such as a mobile telephone, while video content is being viewed, e.g., on a television which is provided video content via a set top box. A knowledgeable moderator can review, supplement, add and delete comments in real time enhancing the overall social networking session.

Abstract: Methods and apparatus for generating, distributing, and/or presenting social networking content in conjunction with video content are described. In accordance with various embodiments, social networking related information, e.g., comments, remarks and/or a twitter feed, are displayed in conjunction with the display of video to which the social networking information relates. The social networking related information may be displayed on the same or a different device from that which is used to display the video comments. In some embodiments, the social networking information, e.g., comments on a program, event or broadcast, are displayed on a personal computer or other device such as a mobile telephone, while video content is being viewed, e.g., on a television which is provided video content via a set top box. A knowledgeable moderator can review, supplement, add and delete comments in real time enhancing the overall social networking session.

Abstract: Methods and apparatus for generating, distributing, and/or presenting social networking content in conjunction with video content are described. In accordance with various embodiments, social networking related information, e.g., comments, remarks and/or a twitter feed, are displayed in conjunction with the display of video to which the social networking information relates. The social networking related information may be displayed on the same or a different device from that which is used to display the video comments. In some embodiments, the social networking information, e.g., comments on a program, event or broadcast, are displayed on a personal computer or other device such as a mobile telephone, while video content is being viewed, e.g., on a television which is provided video content via a set top box. A knowledgeable moderator can review, supplement, add and delete comments in real time enhancing the overall social networking session.

Abstract: Systems and methods for managing data elements on a mobile device that involve identifying a central application with an available set of data elements, for each of a plurality of secondary applications, determining a shared set of data elements where each data element of the shared set of data elements is mapped to a data element of the available set of data elements. The systems and methods may further involve receiving the available set of data elements from the external data storage device for storage in a virtual memory of the mobile device upon detecting that a central application has initialized on the mobile device and populating a secondary application with the shared set of data elements from the virtual memory upon detecting that the secondary application has initialized on the mobile device.

Abstract: Methods and apparatus for generating, distributing, and/or presenting social networking content in conjunction with video content are described. In accordance with various embodiments, social networking related information, e.g., comments, remarks and/or a twitter feed, are displayed in conjunction with the display of video to which the social networking information relates. The social networking related information may be displayed on the same or a different device from that which is used to display the video comments. In some embodiments, the social networking information, e.g., comments on a program, event or broadcast, are displayed on a personal computer or other device such as a mobile telephone, while video content is being viewed, e.g., on a television which is provided video content via a set top box. A knowledgeable moderator can review, supplement, add and delete comments in real time enhancing the overall social networking session.

Abstract: A collapsible, portable motion platform for use with video games, personal computers, simulators, and virtual reality systems is disclosed. The motion platform may include a motion control system including user adjustable regulating devices for setting the range of motion, acceleration and other motion elements in one or more degrees of freedom. The framing may be collapsible and may include an enclosure case. One embodiment of the platform is lightweight and portable, and includes an enclosure case for protection in storage.