Patents by Inventor Sean Macneil

Sean Macneil has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20120149878
    Abstract: Methods of reducing high molecular weight species (HMW) formation in a sample containing a protein purified using ion exchange (IEX) chromatography are disclosed, as are a number of related methods, e.g., methods of reducing on-column denaturation of a protein in a protein sample purified using an ion exchange (IEX) column or resin. The methods share characteristics of including arginine, glycine and/or histidine in the buffers used during the ion exchange (IEX) chromatography.
    Type: Application
    Filed: November 23, 2011
    Publication date: June 14, 2012
    Inventors: Ronald GILLESPIE, Suresh Vunnum, Thao Nguyen, Sean Macneil