Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, thereof: which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A decorative, nonwoven laminate and a method of forming, including a first side of a first nonwoven affixed to one or both of a) a first side of a polymeric sheet or b) a second nonwoven, wherein the first nonwoven exhibits a basis weight of 15 g/m2 to 2500 g/m2 and the second nonwoven exhibits a basis weight of 15 g/m2 to 1200 g/m2; and a colorant deposited on a second side of the first nonwoven. A topical coating may or may not be applied to improve durability of the printed surface layer. The decorative nonwoven laminate may also amount to a single layer of the first nonwoven, which then includes a layer of colorant and a topical coating over the colorant and single nonwoven layer.

Abstract: A method for quantifying amounts of per- and poly-fluoroalkyl substances (PFAS) may use a PFAS detection system comprising a working electrode and one or more processors. The working electrode may have a polymer layer disposed on its surface that comprises a plurality of affinity sites for detecting a plurality of PFAS molecules. Each of the plurality affinity sites may have been created using a template PFAS. The method may comprise detecting, at the working electrode, a plurality PFAS molecules that have bonded to one or more of the plurality of affinity sites; and determining, by the one or more processors and based on the detected plurality of PFAS molecules that are bonded to the one or more affinity sites, a concentration of PFAS in an environment.

Abstract: A door stopping system comprises a mounting member, a supporting member, a leg member, a spring member, a sleeve member, a first pin member and a second pin member. The mounting member is pivotally connected with the supporting member via the first pin member, the leg member is pivotally connected with the supporting member via the second pin member, the mounting member and the leg member are oppositely located to each other along the supporting member, the spring member is biased in between the supporting member and the leg member, and the sleeve member is slidably sleeved on the supporting member. The mounting member is configured to be removably attached to a door. The leg member is configured to contact a ground.

Abstract: A neck assembly for use in an anthropomorphic test device comprising: a first mount disposed at a first end of the neck assembly, the first mount being adapted to be connected to a support structure; a second mount disposed at a second end of the neck assembly, the second mount being adapted to be connected to a test structure such as a surrogate head; and at least one movable joint disposed between the first mount and the second mount, the at least one movable joint being operable to rotate about at least three axes.

Abstract: In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than ?10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.

Abstract: An endoluminal surgical instrument has first and second steering controls on a handle. A flexible shaft attached to the handle has a distal steerable end including a first link and a second link separated by a plurality of intermediate links. First and second steering elements, such as pairs of steering wires, are linked to first and second steering controls and to the first and second links. One or more of the links is pivotable through an angle of at least 30 degrees relative to an adjoining link. The set back position of the second steering elements from the first steering elements, and the pivoting capability of the links allows the steerable end to be steered into a small bend radius. This makes the instrument highly maneuverable for use in endoluminal surgery, such as incision-less surgery of the stomach.

Abstract: A preferred embodiment of the invention is directed to an apparatus and method for mechanically breaking or decompressing blocks of compressed particulate material and, more specifically, to an apparatus and method for breaking apart blocks of coir, peat moss, or similar materials generally used in the horticultural industry. The apparatus can decompress particulate material in a dry state or a wet state without causing physical damage to the material. The apparatus generally comprises a breaking chamber, a rotary breaker assembly, and a screen at the bottom of the chamber through which decompressed material falls. The breaker assembly generally comprises rotary breaker bars, which decompress the particulate material as they rotate. The decompressed material then falls into a discharge chute, where it is then discharged from the apparatus for further use.

Abstract: An endoluminal surgical instrument has first and second steering controls on a handle. A flexible shaft attached to the handle has a distal steerable end including a first link and a second link separated by a plurality of intermediate links. First and second steering elements, such as pairs of steering wires, are linked to first and second steering controls and to the first and second links. One or more of the links is pivotable through an angle of at least 30 degrees relative to an adjoining link. The set back position of the second steering elements from the first steering elements, and the pivoting capability of the links allows the steerable end to be steered into a small bend radius. This makes the instrument highly maneuverable for use in endoluminal surgery, such as incision-less surgery of the stomach.

Abstract: In one aspect, a composition can include an organelle, and a nanoparticle having a zeta potential of less than ?10 mV or greater than 10 mV contained within the organelle. In a preferred embodiment, the organelle can be a chloroplast and the nanoparticle can be a single-walled carbon nanotube associated with a strongly anionic or strongly cationic polymer.

Abstract: An endoluminal surgical instrument has first and second steering controls on a handle. A flexible shaft attached to the handle has a distal steerable end including a first link and a second link separated by a plurality of intermediate links. First and second steering elements, such as pairs of steering wires, are linked to first and second steering controls and to the first and second links. One or more of the links is pivotable through an angle of at least 30 degrees relative to an adjoining link. The set back position of the second steering elements from the first steering elements, and the pivoting capability of the links allows the steerable end to be steered into a small bend radius. This makes the instrument highly maneuverable for use in endoluminal surgery, such as incision-less surgery of the stomach.

Abstract: A potting apparatus has a first conveyor suitable for receiving a pot thereon, a second conveyor has a surface suitable for receiving soil thereon and having an end positioned so as to deliver soil to the pot on the first conveyor, a drill positioned above the first conveyor so as to be movable upwardly and downwardly relative to the pot on the first conveyor so as to form a hole in the pot, and a driving means cooperative with the first conveyor for moving the first conveyor in an indexing manner such that the first conveyor temporarily stops at a location directly below the drill. The drill is slidably supported on a frame so as to be driven by a belt connected to the drill. A servomotor is drivingly connected to the belt so as to move the drill in an upward direction or a downward direction.

Abstract: A potting apparatus has a first conveyor suitable for receiving a pot thereon, a second conveyor has a surface suitable for receiving soil thereon and having an end positioned so as to deliver soil to the pot on the first conveyor, a drill positioned above the first conveyor so as to be movable upwardly and downwardly relative to the pot on the first conveyor so as to form a hole in the pot, and a driving means cooperative with the first conveyor for moving the first conveyor in an indexing manner such that the first conveyor temporarily stops at a location directly below the drill. The drill is slidably supported on a frame so as to be driven by a belt connected to the drill. A servomotor is drivingly connected to the belt so as to move the drill in an upward direction or a downward direction.

Abstract: An endoluminal surgical instrument has first and second steering controls on a handle. A flexible shaft attached to the handle has a distal steerable end including a first link and a second link separated by a plurality of intermediate links. First and second steering elements, such as pairs of steering wires, are linked to first and second steering controls and to the first and, second links. One or more of the links is pivotable through an angle of at least 30 degrees relative to an adjoining link. The set back position of the second steering elements from the first steering elements, and the pivoting capability of the links allows the steerable end to be steered into a small bend radius. This makes the instrument highly maneuverable for use in endoluminal surgery, such as incision-less surgery of the stomach.

Abstract: The present application provides an accelerator device for attaching to a portable electronics device. The portable electronics device communicates using a serial or similar interface with a corresponding interface of the accelerator device. Raw data is transmitted from the portable electronics device for processing by the accelerator device. The accelerator device contains a processor for processing the communicated raw data into processed data and returns the processed data to the portable electronics device. This arrangement allows the processor of the accelerator device to assist the applications processor on the portable electronics device in the processing of data by splitting the processing between the processor of the accelerator device and the portable electronics device.

Abstract: A transition device for placement at the opening of the tip of a cannula body for the purpose of controlling the shape of the cannula tip opening under various loads such as might be encountered during device placement.

Abstract: An adjustable holder for a container comprises a stationery member having a first surface for pressing against a first side of the container. A moveable member has a second surface for pressing against a second side of the container. First and second structures allow the moveable member to telescope with respect to the stationary member along a direction of adjustment. Third and fourth structures set a plurality of distances between the first and second surfaces. The third structure comprises a plurality of slots arranged along the direction of adjustment and oriented generally orthogonal to such direction. The fourth structure comprises a resiliently biased projection with a user-operated handle for being inserted into a desired slot. The holder adjusts to the size of the container, and, in preferred embodiments, can be made especially economically.