Abstract: The invention of the present disclosure provides a method for treating a viral infection in a recipient subject suffering from or at risk of a viral infection including administering to the recipient subject a pharmaceutical composition comprising a therapeutic amount of superactivated cytokine killer T cells (SCKTCs) and a pharmaceutically acceptable carrier, and mobilizing an immune response of the recipient subject to the viral pathogen. When tested in vitro, the SCKTCs are characterized by a predominant production of TH1 dominant cytokines including IFN-?; an IFN-?:IL-4 ratio of at least 500:1; and at least 50% killing of target A549 cells at an effector:target ratio of 20:1.

Abstract: The present disclosure provides, in part, a priming and boosting vector-based platform to develop vaccines against viral pathogens that is tailored to elicit a broad T cell response targeting conserved viral epitopes while including helper T cell (TH) epitopes and an adjuvant to achieve a balanced immune response consisting of both cellular immunity, coupled with a broad neutralizing antibody response in the design of a candidate universal vaccine to HIV or a human coronavirus, e.g., SARS-CoV-2. The universal vaccines are prepared against an immunogen of an infectious pathogenic virus comprising at least one nucleic acid polynucleotide comprising an open reading frame encoding at least one polypeptide antigen or an immunogenic fragment thereof, wherein the polypeptide antigen, or the immunogenic fragment thereof, comprises a conserved internal protein that is enriched in T cell recognition antigens.

Abstract: A device for analyzing and monitoring exercise done by a user comprises at least a portable support (2), electric power supply means, sensor means (3) for measuring the exercise done by the user during at least one predetermined period of time, expressed at least in the form of at least one non-dimensional parameter, at least one memory (4) designed to archive data relating to the measurement of exercise done by the user, display means (5) for displaying the measurement of the exercise done by the user and the data archived in the memory, data communication means (6a), (6b) and at least one processing unit (7a), (7b).

Abstract: A device for analyzing and monitoring exercise done by a user comprises at least a portable support (2), electric power supply means, sensor means (3) for measuring the exercise done by the user during at least one predetermined period of time, expressed at least in the form of at least one non-dimensional parameter, at least one memory (4) designed to archive data relating to the measurement of exercise done by the user, display means (5) for displaying the measurement of the exercise done by the user and the data archived in the memory, data communication means (6a), (6b) and at least one processing unit (7a), (7b).

Abstract: A device for analyzing and monitoring exercise done by a user comprises at least a portable support (2), electric power supply means, sensor means (3) for measuring the exercise done by the user during at least one predetermined period of time, expressed at least in the form of at least one non-dimensional parameter, at least one memory (4) designed to archive data relating to the measurement of exercise done by the user, display means (5) for displaying the measurement of the exercise done by the user and the data archived in the memory, data communication means (6a), (6b) and at least one processing unit (7a), (7b).

Abstract: A trailer (10) for the recovery of vehicles has a drawbar (12) having first and second sections (14,16) hinged together at adjacent ends, about a horizontal transverse axis; the first section (14) of the drawbar (12) has a ball cup (24) by which it may be secured to a towing hitch (100) of a recovery vehicle, the second section (16) of the drawbar (12) has a pair of arms (30) pivotally mounted adjacent the end thereof remote from the end hinged to the first section (14), the arms (30) are pivotal between a stowed position in which they are disposed parallel to the drawbar (12) and a deployed position in which they are disposed coaxially of one another on an axis transverse to the longitudinal axis of the drawbar (12); a pair of wheel pans (50) are mounted and able to slide, one on each of the arms (30), the wheel pans (50) are interconnected to the second section (16) of the drawbar (12) by a linkage mechanism (60, 62), so that when the arms (30) are in the stowed position, the wheel pans (50) are slid inward

Abstract: A trailer (10) for the recovery of vehicles has a drawbar (12) having first and second sections (14,16) hinged together at adjacent ends, about a horizontal transverse axis; the first section (14) of the drawbar (12) has a ball cup (24) by which it may be secured to a towing hitch (100) of a recovery vehicle, the second section (16) of the drawbar (12) has a pair of arms (30) pivotally mounted adjacent the end thereof remote from the end hinged to the first section (14), the arms (30) are pivotal between a stowed position in which they are disposed parallel to the drawbar (12) and a deployed position in which they are disposed coaxially of one another on an axis transverse to the longitudinal axis of the drawbar (12); a pair of wheel pans (50) are mounted and able to slide, one on each of the arms (30), the wheel pans (50) are interconnected to the second section (16) of the drawbar (12) by a linkage mechanism (60, 62), so that when the arms (30) are in the stowed position, the wheel pans (50) are slid inward