Patents by Inventor Sean P. Colgan

Sean P. Colgan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD AND COMPOSITION FOR TREATING GASTROINTESTINAL INFLAMMATORY DISORDERS
    Publication number: 20220133818
    Abstract: Methods of treating, reducing the risk of, preventing, or alleviating a symptom of inflammation or inflammatory gastrointestinal disease by administration of a modified bacterium providing purines, in particular hypoxanthine, to the mucosa of the intestine, and compositions containing modified bacteria useful in such methods.
    Type: Application
    Filed: February 26, 2020
    Publication date: May 5, 2022
    Inventors: Sean P. COLGAN, Joseph Scott LEE, Daniel J. KAO
  • Inflammatory bowel disease therapies
    Patent number: 8962530
    Abstract: The invention relates to methods of treating inflammatory bowel disease in a subject. Methods of promoting intestinal barrier function as well as related compositions are also provided.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: February 24, 2015
    Assignees: Regents of the University of Colorado, The Brigham and Women's Hospital, Inc.
    Inventor: Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Patent number: 8440718
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Grant
    Filed: January 22, 2004
    Date of Patent: May 14, 2013
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Uses of CD116 Expression Level
    Publication number: 20120165220
    Abstract: The present invention provides methods for using granulocyte macrophage colony-stimulating factor receptor (CD116) expression level for various clinical applications including, but not limited to, diagnosing inflammatory bowel disease in a subject.
    Type: Application
    Filed: August 31, 2010
    Publication date: June 28, 2012
    Inventors: Sean P. Colgan, Jonathan Goldstein
  • Approach to anti-microbial host defense with molecular shields with lipoxin compounds
    Patent number: 7994219
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: August 9, 2011
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Approach to anti-microbial host defense with molecular shields with lipoxin compounds
    Patent number: 7915311
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: March 29, 2011
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Sean P. Colgan
  • INFLAMMATORY BOWEL DISEASE THERAPIES
    Publication number: 20110065771
    Abstract: The invention relates to methods of treating inflammatory bowel disease in a subject. Methods of promoting intestinal barrier function as well as related compositions are also provided.
    Type: Application
    Filed: June 26, 2008
    Publication date: March 17, 2011
    Inventor: Sean P. Colgan
  • Approach to antimicrobial host defense with molecular shields with EPA and DHA analogs
    Patent number: 7741368
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. Various BPI inducing agents include icosapentanoic acid (EPA) analogs and docosahexaenoic acid (DHA) analogs.
    Type: Grant
    Filed: February 14, 2006
    Date of Patent: June 22, 2010
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Novel Approach to Anti-Microbial Host Defense with Molecular Shields with Lipoxin Compounds
    Publication number: 20080214665
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds.
    Type: Application
    Filed: August 13, 2007
    Publication date: September 4, 2008
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Compositions and methods for treating hematologic malignancies and multiple drug resistance
    Patent number: 7105656
    Abstract: Methods and compositions are provided for treating a subject having or at risk of developing a hematologic malignancy and/or multiple drug resistance.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: September 12, 2006
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventor: Sean P. Colgan
  • Approach to anti-microbial host defense with molecular shields with EPA and DHA analogs
    Patent number: 7030159
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. Various BPI inducing agents include icosapentanoic acid (EPA) analogs and docosahexaenoic acid (DHA) analogs.
    Type: Grant
    Filed: December 18, 2002
    Date of Patent: April 18, 2006
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Patent number: 6699905
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Grant
    Filed: September 24, 2002
    Date of Patent: March 2, 2004
    Assignee: Brigham and Women's Hospital
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Novel approach to anti-microbial host defense with molecular shields with lipoxin compounds
    Publication number: 20030195248
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. The BPI inducing agents include, for example, lipoxin compounds.
    Type: Application
    Filed: December 18, 2002
    Publication date: October 16, 2003
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Novel approach to anti-microbial host defense with molecular shields with EPA and DHA analogs
    Publication number: 20030191184
    Abstract: Methods to cause tissue, such as mucosal cells, to express increased amounts of bactericidal permeability increasing protein (BPI) are described. Various BPI inducing agents include icosapentanoic acid (EPA) analogs and docosahexaenoic acid (DHA) analogs.
    Type: Application
    Filed: December 18, 2002
    Publication date: October 9, 2003
    Inventors: Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Publication number: 20030060512
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Application
    Filed: September 24, 2002
    Publication date: March 27, 2003
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Patent number: 6458839
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Grant
    Filed: October 5, 2001
    Date of Patent: October 1, 2002
    Assignee: The Brigham and Women's Hospital
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Publication number: 20020045579
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Application
    Filed: October 5, 2001
    Publication date: April 18, 2002
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to Columnar epithelia
    Patent number: 6329425
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Grant
    Filed: October 21, 1997
    Date of Patent: December 11, 2001
    Assignee: Brigham and Women's Hospital
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Patent number: 6177468
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Grant
    Filed: February 2, 2000
    Date of Patent: January 23, 2001
    Assignee: The Brigham and Women's Hospital, Inc.
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan
  • Modulation of inflammation related to columnar epithelia
    Patent number: 6100296
    Abstract: This invention provides pharmaceutical compositions containing lipoxin compounds and therapeutic uses for the compounds in treating or preventing a disease or condition associated with columnar epithelial inflammation. The invention also discloses methods for screening for compounds useful in preventing columnar epithelial inflammation.
    Type: Grant
    Filed: February 25, 1997
    Date of Patent: August 8, 2000
    Assignee: The Brigham Women's Hospital, Inc.
    Inventors: James L. Madara, Charles N. Serhan, Sean P. Colgan