Abstract: The device includes an elongate shaft having a distal end coupled to a proximal end of an articulation joint, and an actuation wire extending through the elongate shaft and the articulation joint. The device includes an end effector having a distal tip coupled to a distal end of the articulation joint and receiving therethrough a distal end of the actuation wire. The end effector includes a hook knife disposed adjacent the distal tip and having a proximal end connected to the distal end of the actuation wire. The actuation wire is translatable along a longitudinal axis of the elongate shaft to extend and retract the distal end of the hook knife relative to the distal tip of the end effector, and the articulation joint is laterally articulatable relative to the longitudinal axis of the elongate shaft to allow the end effector to be angularly oriented relative to the elongate shaft.

Abstract: Various methods and devices are provided for penetrating tissue. In one embodiment, a tissue-penetrating device is provided and includes a flexible hollow elongate shaft having a tissue-penetrating tip at a distal end thereof, and a plunger disposed within the tissue-penetrating tip. The plunger can be movable relative to the tissue-penetrating tip between a distal position in which the plunger is distal of the tissue-penetrating tip to prevent tissue penetration, and a proximal position in which the plunger is proximal of the tissue-penetrating tip to allow the tip to penetrate tissue. The plunger can be adapted to move from the distal position to the proximal position when the plunger is advanced into a tissue surface. The device can also include a biasing element coupled to the plunger that can be adapted to bias the plunger to the distal position. The biasing element can be coupled between a distal end of a stylet that extends through the hollow elongate shaft, and a proximal end of the plunger.

Abstract: In one general aspect, various embodiments are directed to methods for treating tissue within an aqueous environment. Various methods may include introducing a cutting implement of a surgical instrument into the aqueous environment. The cutting implement may have at least one cutting surface thereon and at least one ultrasonic portion thereon and be selectively rotatable within a hollow sheath. The methods may include rotating or rotatably oscillating the cutting implement within the hollow sheath for tissue cutting purposes. The cutting implement may also be retained in a position wherein the ultrasonic portion of the cutting implement may be applied to tissue and then have ultrasonic motion applied thereto.

Abstract: Methods and devices are provided for controlling movement of a working end of a surgical device, and in particular for performing various surgical procedures using an instrument having an end effector that can be articulated relative to an elongate shaft of the device. In certain embodiments, the end effector can also optionally rotate relative to the elongate shaft of the device, and/or the shaft can rotate relative to a handle of the device.

Abstract: A tissue thickness compensator can comprise a plurality of layers. Various embodiments are disclosed herein for manufacturing a tissue thickness compensator.

Abstract: A tissue thickness compensator may generally comprise a first layer comprising a first biocompatible material sealingly enclosed in a water impermeable material and a second layer comprising a second biocompatible material comprising at least one encapsulation, wherein the first biocompatible material expands when contacted with a fluid. The tissue thickness compensator may comprise a haemostatic agent, an anti-inflammatory agent, an antibiotic agent, anti-microbial agent, an anti-adhesion agent, an anti-coagulant agent, a medicament, and/or pharmaceutically active agent. The encapsulation may comprise a biodegradable material to degrade in vivo and/or in situ. The tissue thickness compensator may comprise a hydrogel. The reaction product may comprise a fluid-swellable composition. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.

Abstract: A device for manipulating a magnetic coupling force across tissue in response to a monitored coupling force is described. The device includes a magnetic field source assembly, a positioning assembly operatively connected to the magnetic field force assembly, and a magnetic coupling force monitor. The magnetic field source assembly includes magnets that provide an external magnetic field source for providing a magnetic field across tissue. The positioning assembly adjusts the position of the magnetic field source. The magnetic field creates a magnetic coupling force between the external magnetic field source and an object positioned in use in a patient during a procedure, wherein the object has or is associated with an internal magnetic field.

Abstract: Various powering devices are provided for transferring and/or generating energy from numerous sources to a communicating member implanted in a patient. The energy transferred to or generated by the communicating member can be used to provide power to an implantable restriction system configured to form a restriction in a pathway.

Abstract: Rotational couplers for use with surgical devices that are actuated by semi-flexible actuators such as wires and the like. The couplers enable the actuators to apply various actuation motions to actuation features on the surgical device as well as other actuators to apply axial and rotational motions to the surgical device to manipulate the device into various orientations relative to an elongate shaft to which the device is movably attached.

Abstract: An injection port comprises a body, a fluid reservoir, a septum, and a plurality of fasteners. The fluid reservoir is defined in part by the body and the septum. A needle may be inserted through the septum to reach the reservoir. The fasteners are integral with the body. The fasteners are simultaneously rotatable from a non-deployed position to a deployed position. The fasteners are retracted relative to the body when the fasteners are in the non-deployed position. The fasteners are extended relative to the body when the fasteners are in the deployed position. The fasteners are also simultaneously rotatable from the deployed position to the non-deployed position. The injection port may be coupled with a gastric band via a conduit. The conduit may provide fluid communication between an inflatable member of the gastric band and the reservoir of the injection port as part of a closed fluid circuit.

Abstract: A method for repairing or modifying an area of a patient's anatomy that comprises directing at least a portion of a scanning beam assembly to an area of a patient's anatomy, applying a radiation-responsive agent to portion of the anatomy, and exposing the radiation-responsive agent to radiation directed onto the agent by the reflector to cause the agent to therapeutically interact with the site. The scanning beam assembly including a radiation source capable of emitting radiation, a reflector that receives the radiation from the radiation source to direct the radiation onto the anatomy, wherein the reflector oscillates in at least two directions to create a scan of the anatomy, a detector to detect radiation returned from the anatomy, and a controller to convert the detected radiation into a displayable anatomy image.

Abstract: Rotational couplers for use with surgical devices that are actuated by semi-flexible actuators such as wires and the like. The couplers enable the actuators to apply various actuation motions to actuation features on the surgical device as well as other actuators to apply axial and rotational motions to the surgical device to manipulate the device into various orientations relative to an elongate shaft to which the device is movably attached.

Abstract: An electrosurgical device comprises a body, an end effector, a cutting member, and a shaft extending between the body and the end effector. The end effector includes a pair of jaws and at least one electrode operable to deliver RF energy to tissue clamped between the jaws. The cutting member is operable to cut tissue clamped between the jaws. The shaft includes an articulation section that is operable to selectively position the end effector at non-parallel positions relative to the longitudinal axis of the shaft. The articulation section may include beads, segments, asymmetric features, preformedly bent features, an integral hinge, a helical cutout or spring, clevis features, an angled joint, a beaded actuation linkage, and/or an offset pivot, among other things. The device may also include a crimped cutting member, a retroacting cutting member, dual pivoting jaws, and/or a wire tensioning assembly.

Abstract: A surgical device comprises an ex vivo magnet and an in vivo sled magnetically attracted to the ex vivo magnet. The sled can be positioned and anchored within a patient by moving the ex vivo magnet. The sled defines a longitudinal axis. An arm extends from the sled. The arm is moveable relative the sled between a retracted position and an extended position. The arm comprises an end effector. A locking mechanism operatively connected to the arm to lock the arm in the retracted and extended positions. The mechanism may include a rack that both rotates about a pinion and translates tangentially about the pinion.

Abstract: A surgical kit comprises two percutaneous instruments each having an elongate shaft with a distal end and a proximal end connected to a handle; at least two end effectors attachable and detachable to the distal ends of the percutaneous instruments; a laparoscopic loader adapted to receive the end effectors; a trocar; and a laparoscopic surgical stapler. The surgical kit may further comprise laparoscopic energy based clamping and coagulating device and/or a laparoscopic suture device. Optionally, the surgical kit may further comprised a third percutaneous instrument having an elongate shaft with a distal end and a proximal end connected to a handle, and at least three end effectors attachable and detachable to the distal ends of the percutaneous instruments. The surgical kit may further comprise a magnetic camera and/or a magnetic external control unit adapted to anchor a magnetic camera. The components of the surgical kit may be contained in a sterile sealed package.

Abstract: A single port surgical method comprises inserting only a single trocar through the abdominal wall; inserting a camera into the abdominal cavity; magnetically anchoring the camera to the abdominal wall; obtaining a first instrument comprising an elongate shaft with a distal end and a proximal end connected to a first handle; passing the distal end of the first instrument through the abdominal wall independent of a trocar; attaching in vivo an end effector to the distal end of the first surgical instrument; obtaining a second instrument comprising an elongate shaft with a distal end with an end effector and a proximal end connected to a second handle; passing the distal end of the second instrument through the trocar; and manipulating tissue in the abdominal cavity with the first and second surgical instrument end effectors under visualization from the magnetically anchored camera.

Abstract: Methods and devices reroute chyme to induce intestinal brake in order to improve the effectiveness of bariatric surgical procedures and to improve comorbidity resolution. A bowel is manipulated to provide a shortened path for chyme to travel to the ileum. These methods and devices of rerouting chyme to induce intestinal brake may comprise one or more of a surgical procedure, an implanted device, or a combination of an implant with an improved surgical procedure.

Abstract: A method for regulating hormone production comprises placing at least one electrode in a gastrointestinal tract of a patient and recording an electrical signal during a preselected event produced by the gastrointestinal tract. The method further involves the steps of storing the electrical signal, and playing back the electrical signal by activating the electrode during the absence of the preselected event.

Abstract: Methods and devices create an intestinal braking effect, are non-invasive or minimally invasive, and may be reversible. These methods and devices are accomplished via stabilized implantable systems, and ingestible pills. In one embodiment, the implantable system comprises a device delivering a therapeutic substance to a target location within the gastrointestinal tract of a patient in order to initiate an intestinal braking effect which would promote sensations of satiety and stimulate excess weight loss for the patient.

Abstract: Methods described herein involve introducing a nasogastric tube into a patient, connecting the nasogastric tube with a reservoir, anchoring the nasogastric tube with the nasal cavity, and introducing a substance into the reservoir through the nasogastric tube.