Abstract: Methods and systems for providing characters on a blockchain as NFTs are provided. A character NFT may include one or more skeletal structures, one or more skins, and/or one or more animations. A character NFT may be advantageously utilized in cross-platform applications.

Abstract: The present invention is based, in part, on flagellin adjuvant used to enhance immune responses directed against Streptococcus pneumoniae, in particular, to enhance immune responses to polypeptide antigens (e.g., PspA) and capsular polysaccharide from S. pneumoniae. In representative embodiments, the invention provides a fusion protein comprising a flagellin adjuvant and one more polypeptide antigens from S. pneumoniae. In other embodiments, the invention provides a conjugate comprising a flagellin adjuvant covalently linked to a capsular polysaccharide from one or more serotypes of S. pneumoniae. Also provided are compositions comprising the fusion proteins and/or conjugates of the invention as well as immunogenic formulations comprising the inventive fusion proteins, conjugates and/or compositions. The invention also provides methods of producing an immune response against S. pneumoniae and methods of protecting a subject from S.

Abstract: The present invention provides a colored solar reflective system comprising (1) a particulate material having a substantially rutile crystal habit and having an average particle size of between about 0.5 ?m and about 2.0 ?m and (2) an organic pigment having a maximum absorption coefficient of about 5,000 mm?1 or greater in the visible light region, a maximum scattering coefficient of about 500 mm?1 or less in the visible light region and an average absorption coefficient of about 50 mm?1 or less in the infrared region. The solar reflective system, which may be used in a coating composition or as a composition from which articles can be formed, exhibits a dark, intense color while also providing enhanced total solar reflectance.

Abstract: The present invention is based, in part, on flagellin adjuvant used to enhance immune responses directed against Streptococcus pneumoniae, in particular, to enhance immune responses to polypeptide antigens (e.g., PspA) and capsular polysaccharide from S. pneumoniae. In representative embodiments, the invention provides a fusion protein comprising a flagellin adjuvant and one more polypeptide antigens from S. pneumoniae. In other embodiments, the invention provides a conjugate comprising a flagellin adjuvant covalently linked to a capsular polysaccharide from one or more serotypes of S. pneumoniae. Also provided are compositions comprising the fusion proteins and/or conjugates of the invention as well as immunogenic formulations comprising the inventive fusion proteins, conjugates and/or compositions. The invention also provides methods of producing an immune response against S. pneumoniae and methods of protecting a subject from S.