Patents by Inventor Sean S. Davies

Sean S. Davies has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF 2-HOBA TO TREAT ATHEROSCLEROSIS
    Publication number: 20230364032
    Abstract: A method of treating familial hypercholesterolemia accelerated atherosclerosis in a subject in need thereof, comprising administering an effective amount of a dicarbonyl scavenger.
    Type: Application
    Filed: June 1, 2021
    Publication date: November 16, 2023
    Inventors: MacRae F. Linton, Sean S. Davies, Olivier Boutaud
  • Methods for treating atherosclerosis with gamma-ketoaldehyde scavengers
    Patent number: 11389414
    Abstract: A method of treating atherosclerosis, comprising administering to a patient in need there of an effective gamma-ketoaldehyde scavenging amount of a gamma-ketoaldehyde scavenging compound.
    Type: Grant
    Filed: April 27, 2018
    Date of Patent: July 19, 2022
    Assignee: Vanderbilt University
    Inventors: Macrae F. Linton, John A. Oates, Sean S. Davies, L. Jackson Roberts, II, Venkataraman Amarnath, Patricia G. Yancey, Huan Tao
  • METHODS FOR TREATING ATHEROSCLEROSIS WITH GAMMA-KETOALDEHYDE SCAVENGERS
    Publication number: 20200138747
    Abstract: A method of treating atherosclerosis, comprising administering to a patient in need there of an effective gamma-ketoaldehyde scavenging amount of a gamma-ketoaldehyde scavenging compound.
    Type: Application
    Filed: April 27, 2018
    Publication date: May 7, 2020
    Inventors: MacRae F. Linton, John A. Oates, Sean S. Davies, L. Jackson Roberts, II, Venkataraman Amarnath, Patricia G. Yancey, Huan Tao
  • Controlling appetite, promoting weight loss, reducing body fat, and/or improving glucose tolerance
    Patent number: 9795640
    Abstract: A method for treating obesity, insulin sensitivity, and related conditions involves administering to the subject a bacterium for overexpressing a N-acyl-phosphatidylethanolamine (NAPE) and/or a N-acylethanolamine (NAE). A composition includes a bacterium for overexpressing a N-acyl-phosphatidylethanolamine (NAPE) and/or a N-acylethanolamine (NAE); and an ingestible vehicle in which the bacterium is provided.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: October 24, 2017
    Assignee: Vanderbilt University
    Inventors: Sean S. Davies, Zhongyi Chen, Lilu Guo, Yongqin Zhang
  • Isoketal scavengers and mitigation of disorders involving oxidative injury
    Patent number: 8822542
    Abstract: A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
    Type: Grant
    Filed: February 27, 2009
    Date of Patent: September 2, 2014
    Assignee: Vanderbilt University
    Inventors: L. Jackson Roberts, II, Jeffrey R. Balser, Sean S. Davies, Venkataraman Amarnath, Prakash C. Viswanathan
  • CONTROLLING APPETITE, PROMOTING WEIGHT LOSS, REDUCING BODY FAT, AND/OR IMPROVING GLUCOSE TOLERANCE
    Publication number: 20140219965
    Abstract: A method for treating obesity, insulin sensitivity, and related conditions involves administering to the subject a bacterium for overexpressing a N-acyl-phosphatidylethanolamine (NAPE) and/or a N-acylethanolamine (NAE). A composition includes a bacterium for overexpressing a N-acyl-phosphatidylethanolamine (NAPE) and/or a N-acylethanolamine (NAE); and an ingestible vehicle in which the bacterium is provided.
    Type: Application
    Filed: September 19, 2012
    Publication date: August 7, 2014
    Applicant: VANDERBILT UNIVERSITY
    Inventors: Sean S. Davies, Zhongyi Chen, Lilu Guo, Yongqin Zhang
  • ISOKETAL SCAVENGERS AND MITIGATION OF DISORDERS INVOLVING OXIDATIVE INJURY
    Publication number: 20120157501
    Abstract: A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
    Type: Application
    Filed: February 27, 2009
    Publication date: June 21, 2012
    Inventors: L. Jackson Roberts, II, Jeffrey R. Balser, Sean S. Davies, Venkataraman Amarnath, Prakash C. Viswanathan
  • Method of preventing and/or treating oxidant injury in neurodegenerative and oxidative diseases
    Patent number: 7705054
    Abstract: A method of treating and/or preventing oxidative damage, comprising administering an effective IsoK/NeuroK adduct formation suppressing amount of a phenolic amine compound and/or pyridoxamine or pyridoxamine analog, including embodiments where the phenolic compound is at least one of a pyridoxamine, salicylamine, tyrosine compound or an analog thereof.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: April 27, 2010
    Assignee: Vanderbilt University
    Inventors: L. Jackson Roberts, II, Jeffrey R. Balser, Sean S. Davies, Prakash C. Viswanathan, Venkataraman Amarnath