Patents by Inventor Sean Trapp

Sean Trapp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-carboxypropyl-aminotetralin derivatives and related compounds as mu opioid receptor antagonists
    Patent number: 8318765
    Abstract: The invention provides 3-carboxypropyl-aminotetralin compounds of formula (I): wherein R1, R2, R3, R4, R5, and R6 are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are antagonists at the mu opioid receptor. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat conditions associated with mu opioid receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Grant
    Filed: December 19, 2011
    Date of Patent: November 27, 2012
    Assignee: Theravance, Inc.
    Inventors: Sean Trapp, Michael R. Leadbetter, Daniel D. Long, John R. Jacobsen, Priscilla Van Dyke
  • Glycopeptide derivatives and pharmaceutical compositions containing the same
    Publication number: 20080103292
    Abstract: Disclosed are derivatives of glycopeptide compounds having at least one substituent of the formula: —Ra—Y—Rb-(Z)x where Ra, Rb, Y, Z and x are as defined, and pharmaceutical compositions containing such glycopeptide derivatives. The disclosed glycopeptide derivatives are useful as antibacterial agents.
    Type: Application
    Filed: October 24, 2007
    Publication date: May 1, 2008
    Inventors: J. Judice, Paul Fatheree, Bernice Lam, Michael Leadbetter, Martin Linsell, YongQi Mu, Sean Trapp, Guang Yang, Yan Zhu
  • Aryl aniline beta2 adrenergic receptor agonists
    Publication number: 20070225329
    Abstract: The invention provides novel ?2 adrenergic receptor agonist compounds of formula (I): wherein R1-R13 and w have any of the values described in the specification. The invention also provides combinations of such compounds and other therapeutic agents, pharmaceutical compositions comprising such compounds and combinations, methods of using such compounds to treat diseases associated with ?2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: May 22, 2007
    Publication date: September 27, 2007
    Inventors: Edmund Moran, John Jacobsen, Michael Leadbetter, Matthew Nodwell, Sean Trapp, James Aggen, Timothy Church
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20060189517
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: April 17, 2006
    Publication date: August 24, 2006
    Inventors: Paul Fatheree, Martin Linsell, Daniel Marquess, Sean Trapp, Edmund Moran, James Aggen
  • CROSS-LINKED GLYCOPEPTIDE-CEPHALOSPORIN ANTIBIOTICS
    Publication number: 20050209132
    Abstract: This invention provides cross-linked glycopeptide-cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: October 18, 2004
    Publication date: September 22, 2005
    Inventors: Daniel Marquess, Martin Linsell, S. Turner, Sean Trapp, Daniel Long, Paul Fatheree
  • Aryl aniline derivatives as beta2 adrenergic receptor agonists
    Publication number: 20050159448
    Abstract: The invention provides novel ?2 adrenergic receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with ?2 adrenergic receptor activity, and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: January 11, 2005
    Publication date: July 21, 2005
    Inventors: Robert McKinnell, John Jacobsen, Sean Trapp, Daisuke Saito
  • Cross-linked glycopeptide-cephalosporin antibiotics
    Publication number: 20050026818
    Abstract: This invention provides cross-linked glycopeptide—cephalosporin compounds and pharmaceutically acceptable salts thereof which are useful as antibiotics. This invention also provides pharmaceutical compositions containing such compounds; methods for treating bacterial infections in a mammal using such compounds; and processes and intermediates useful for preparing such compounds.
    Type: Application
    Filed: July 9, 2004
    Publication date: February 3, 2005
    Inventors: Paul Fatheree, Martin Linsell, Daniel Marquess, Sean Trapp, Edmund Moran, James Aggen