Abstract: A venous ablation device (1) for denuding a vessel wall (9). The venous ablation device (1) comprises a bristle portion (2). The bristle portion (2) comprises a core (3) and a plurality of resiliently flexible bristles (4) extending at least radially outwardly from the core (3), the bristles (4) having a collapsed delivery configuration and an expanded deployed configuration in which the bristles (4) are configured to contact and denude the vessel wall (9). The venous ablation device (1) further comprises a delivery portion (5) configured to deliver the bristle portion (2) through a delivery catheter (7). The delivery portion (5) at least partially integral with the core (3). The plurality of bristles (4) penetrate through the core (3) such that the core (3) secures the bristles (4).

Abstract: The present disclosure is directed to a vascular device comprising a catheter and a structure as well as a movable macerator. The structure is provided at a distal part of the catheter and comprises a disengaging portion configured to disengage vascular debris from a vessel wall, and a collecting portion configured to collect removed vascular debris. The movable macerator is located at least partially within the structure and/or proximal to the structure and configured to macerate removed vascular debris, so that the device is configured to macerate vascular debris by way of movement of the macerator for facilitating entry into the opening and/or conveyance through the lumen.

Abstract: An apparatus comprises an embolisation device (100) for promoting clot formation in a bodily lumen (800). The embolisation device (100) comprises a core (200) and a plurality of flexible bristles (400) extending outwardly from the core (200), the bristles (400) having a collapsed delivery configuration and an expanded deployed configuration in which the bristles extend at least radially outwardly from the core (200) to contact the lumen (800) and to anchor the device (100) in the lumen (800). The embolisation device (100) is configured to be delivered in a distal direction from a delivery catheter (750) to the lumen (800). In the expanded deployed configuration, a set of the flexible bristles (400a) extend radially outwardly from the core (200) and longitudinally in a proximal direction (P) opposite to the distal direction. The apparatus further comprises a recapture mechanism (111) for moving the set of flexible bristles (400a) to a lower radial profile than in the expanded deployed configuration.

Abstract: A balloon (12) having a drug carried on a working surface (W) of the balloon wall and a radiopaque identifier (30) identifying the location of the drug (D) on the balloon (12), wherein a portion of the balloon is coated with a radiopaque material to which a drug formulation adheres, and uncoated areas are not covered by the drug (D) or the drug (D) is adhered to the working surface (W), that is not treated with radiopaque material.

Abstract: A flow restrictor (50) for an embolization device (10), the flow restrictor having an inner hole (52) for receiving a stem (20) of the embolization device to mount the flow restrictor on the embolization device, wherein the flow restrictor comprises: a membrane (56) for restricting flow in the bodily lumen, having a first elasticity; and a reinforcing section (54) having a second elasticity and at least partially surrounding the inner hole.

Abstract: There is provided a laminate membrane for an implant, comprising: an inner layer having an inner layer thickness; a first covering layer disposed on one side of the inner layer, the first covering layer having a first covering layer thickness; and a second covering layer disposed on another side of the inner layer, the second covering layer having a second covering layer thickness.

Abstract: A balloon catheter adapted for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including first and second spaced ends and a working surface between the ends. An insert located within the interior compartment of the balloon includes at least a radiopaque portion separate from the shaft. Related methods are also disclosed.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.

Abstract: There is provided a laminate membrane for an implant, comprising: an inner layer having an inner layer thickness; a first covering layer disposed on one side of the inner layer, the first covering layer having a first covering layer thickness; and a second covering layer disposed on another side of the inner layer, the second covering layer having a second covering layer thickness.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.

Abstract: There is provided a laminate membrane for an implant, comprising: an inner layer having an inner layer thickness; a first covering layer disposed on one side of the inner layer, the first covering layer having a first covering layer thickness; and a second covering layer disposed on another side of the inner layer, the second covering layer having a second covering layer thickness.

Abstract: A balloon catheter includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including first and second spaced conical end sections and a working surface between the conical sections. The balloon further includes at least one radiopaque marking identifying the transition from the conical end section to the working surface. Related aspects are also disclosed.

Abstract: A balloon catheter for use in connection with a guidewire comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end, and inflatable balloon supported, along the distal end of the shaft, the balloon when inflated including first and second spaced ends and a working surface between the ends, and at least one wire including at least a radiopaque portion for identifying the location of working surface of the balloon.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.

Abstract: There is provided a laminate membrane for an implant, comprising: an inner layer having an inner layer thickness; a first covering layer disposed on one side of the inner layer, the first covering layer having a first covering layer thickness; and a second covering layer disposed on another side of the inner layer, the second covering layer having a second covering layer thickness.

Abstract: A balloon catheter adapted for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including first and second spaced ends and a working surface between the ends. An insert located within the interior compartment of the balloon includes at least a radiopaque portion separate from the shaft. Related methods are also disclosed.

Abstract: A balloon catheter adapted for use with a guidewire includes an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including first and second spaced ends and a working surface between the ends. An insert located within the interior compartment of the balloon includes at least a radiopaque portion separate from the shaft. Related methods are also disclosed.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.

Abstract: A balloon catheter comprises an elongated, tubular shaft extending in a longitudinal direction, said shaft having a proximal end and a distal end. An inflatable balloon is supported along the distal end of the shaft, the balloon when inflated including a generally cylindrical barrel section forming a working surface, and generally conical end sections that do not form a part of the working surface. The balloon further includes at least one radiopaque identifier for indicating the relative position of the working surface, said identifier being provided on at least one of the conical end sections of the balloon so as to define the extent of the working surface. Related aspects are also disclosed.