Abstract: Systems, methods, and other embodiments described herein relate to specialized hardware accelerators for deep learning tasks. In one embodiment, a system includes a first waveguide and a second waveguide. The first waveguide is spaced from the second waveguide. The system includes a first phase tuning component, a second phase tuning component, and a signal mixing component. The first phase tuning component includes a first ring resonator that is coupled to the first waveguide. The second phase tuning component includes a second ring resonator that is coupled to the second waveguide. The signal mixing component includes at least a third ring resonator and a fourth ring resonator. The third ring resonator is coupled to the first waveguide and the fourth ring resonator is coupled to the second waveguide. Further, the third ring resonator and the fourth ring resonator are coupled to each other.

Abstract: The present invention discloses compounds of Formula (I), or pharmaceutically acceptable salts, which inhibit the cellular entry of hepatitis B virus (HBV) and/or hepatitis D virus (HDV) or interfere with the function of the life cycle of HBV and/or HDV and are also useful as antiviral agents. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject suffering from HBV and/or HDV infection. The invention also relates to methods of treating an HBV and/or HDV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

Abstract: A dual ring resonator including a base substrate, and a silicon oxide layer positioned on the base substrate having a first waveguide, a primary ring resonator optically coupled to the first waveguide, a second waveguide, and a secondary ring resonator optically coupled to the primary ring resonator and the second waveguide. The dual ring resonator further includes at least one heater disposed partially on the primary ring resonator, and a trench within at least the silicon oxide layer and surrounding at least a portion of the first waveguide and the second waveguide.

Abstract: This disclosure relates to protein complexes targeting CD47, PD-L1, and/or TGF?, and methods of use thereof. In one aspect, the protein complexes include one or more CD47-binding domains, each including all or a portion of the SIRP? extracellular region; one or more PD-L1-binding domains, each including all or a portion of the PD-1 extracellular region; and optionally one or more TGF?-binding domains, each including all or a portion of the TGF?R2 extracellular region.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices that lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstructions for dissection tools. In particular, the present disclosure relates to devices that transition from a constrained to an unconstrained bowed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices that lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstructions for dissection tools. In particular, the present disclosure relates to devices that transition from a constrained to an unconstrained bowed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: This application describes systems and methods for generating machine learning models (MLMs). An exemplary method includes obtaining a sample and user input data characterizing a product or service. A subset of the data is selected from the sample based on sampling the sample according to the user input data. An MLM is trained by applying the data subset as training input to the MLM, thereby providing a trained MLM to emulate a customer selection process unique to the product or service. A user interface (UI) configured to receive other user input data and cause the trained MLM to execute on the other user input data, thereby testing the trained MLM, is presented. A summary of results from the execution of the trained MLM is generated and presented in the UI. The summary of results indicates a contribution to the trained MLM of each of a plurality of features.

Abstract: Sensor systems can be used to measure an analyte concentration. Sensor systems can include a base having a distal side configured to face towards a person's skin. An adhesive can couple the base to the skin. A transcutaneous analyte measurement sensor can be coupled to the base and can be located at least partially in the host. A transmitter can be coupled to the base and can transmit analyte measurement data to a remote device.

Abstract: Various systems and methods for managing disposable sensors and electrode gel are disclosed. According to an embodiment, a sensor assembly configured to be attached to a patient includes one or more electrode modules. Each of the one or more electrode modules includes an electrode, electrode gel disposed in a storage location on the electrode module, wherein electrode gel is not in contact with the electrode in the storage location, and a deformable cap configured to move the electrode gel from the storage location into contact with the electrode in response to a deformation of the deformable cap.

Abstract: A computer system includes physical memory devices of different types that store randomly-accessible data in memory of the computer system. In one approach, access to memory in an address space is maintained by an operating system of the computer system. A virtual page is associated with a first memory type. A page table entry is generated to map a virtual address of the virtual page to a physical address in a first memory device of the first memory type. The page table entry is used by a memory management unit to store the virtual page at the physical address.

Abstract: This disclosure provides methods for producing T cells with shortened ex vivo manufacturing time. In particular, this disclosure involves the production of T cells from hematopoietic stem cells with the proviso that the process does not involve subsequent in vitro steps of activation and/or expansion of the T cells.

Abstract: In one instance, a heating pad is disclosed that is flexible, battery-power, and weighted. The heating pad includes a sleeve formed with a top layer and a bottom layer and having an interior. A weighted segment layer is disposed within the interior of the sleeve. The weighted segment layer may include a plurality of pockets each having a plurality of weights. A conductive layer or sheet is disposed within the interior of the sleeve closer to the user than the weighted segment layer when in the deployed position. A battery and control unit is electrically coupled to the conductive layer for selectively providing power to the conductive layer. At least one temperature sensor is coupled to the conductive layer and electrically coupled to the control unit and provides safety features. Other heating pads are presented.

Abstract: A cover for an underground enclosure may include an upper surface comprising a pattern of bosses, a first slot and a second slot disposed on the upper surface, a lower surface opposite the upper surface. A first reinforcement member may be coupled to the lower surface. The first slot may extend into the first reinforcement member, and a second reinforcement member may be coupled to the lower surface and aligned with the first reinforcement member. The second slot may extend into the second reinforcement member. The cover may be configured to be lifted by the first slot and the second slot.

Abstract: A method for integrating audio recording and distributing. The method can include: detecting a user interface selection made by a user of a computing device; recording an audio snippet in response to the user interface selection; generating, by the first computing device, a social network message including an indication of the audio snippet; and transmitting the social network message to an external server for broadcasting to a set of user accounts of a real-time messaging platform.

Abstract: Methods and apparatuses are described for enterprise access control governance in a computerized information technology (IT) architecture. A server generates a first vector space, each node in the first space representing a user of resources in the IT architecture and including attributes of the user. The server generates a second vector space, each node in the second space representing an entitlement to access resources in the IT architecture and including attributes of the entitlement. The server creates an entitlement utility matrix by mapping nodes in the first space to nodes in the second space. The server determines a set of recommended entitlements for a plurality of users based upon the utility matrix. The server determines a discrepancy between the set of recommended entitlements for a first user and a set of existing entitlements for the first user and adjusts the set of existing entitlements based upon the discrepancy.

Abstract: Methods and apparatuses are described for enterprise access control governance in a computerized information technology (IT) architecture. A server generates a first vector space, each node in the first space representing a user of resources in the IT architecture and including attributes of the user. The server generates a second vector space, each node in the second space representing an entitlement to access resources in the IT architecture and including attributes of the entitlement. The server creates an entitlement utility matrix by mapping nodes in the first space to nodes in the second space. The server determines a set of recommended entitlements for a plurality of users based upon the utility matrix. The server determines a discrepancy between the set of recommended entitlements for a first user and a set of existing entitlements for the first user and adjusts the set of existing entitlements based upon the discrepancy.

Abstract: Methods and apparatuses are described for enterprise access control governance in a computerized information technology (IT) architecture. A server generates a first vector space, each node in the first space representing a user of resources in the IT architecture and including attributes of the user. The server generates a second vector space, each node in the second space representing an entitlement to access resources in the IT architecture and including attributes of the entitlement. The server creates an entitlement utility matrix by mapping nodes in the first space to nodes in the second space. The server determines a set of recommended entitlements for a plurality of users based upon the utility matrix. The server determines a discrepancy between the set of recommended entitlements for a first user and a set of existing entitlements for the first user and adjusts the set of existing entitlements based upon the discrepancy.

Abstract: The invention features, in general, a method for determining a target cycle time for an injection molded part. The method comprises the steps of ascertaining the solidified volume percentage (Vn) as a function of cooling time (Tn) data for solidification of an injection molded part and calculating a cooling speed indicator (CSIn) for each data point, (Tn,Vn). The solidified volume percentage (Vn) as a function of cooling time (Tn) and solidified volume percentage (Vn) as a function of cooling speed indicator (CSIn) are tabulated and used to determine a target cycle time.

Abstract: A connecting terminal is disclosed having a wire connection portion with at least one pair of side arms, and an abutting portion attached at a second end to the wire connection portion. The Abutting portion includes at least one mating terminal receiving chamber and a locking structure. The locking structure includes a locking surface facing the wire connection portion and extending perpendicularly to an insertion direction of the connecting terminal, a first locking surface formed on an upper side of the abutting portion and a second locking surface formed on a lower side of the second end of the abutting portion.

Abstract: The invention features, in general, a method for determining a target cycle time for an injection molded part. The method comprises the steps of ascertaining the solidified volume percentage (Vn) as a function of cooling time (Tn) data for solidification of an injection molded part and calculating a cooling speed indicator (CSIn) for each data point, (Tn,Vn). The solidified volume percentage (Vn) as a function of cooling time (Tn) and solidified volume percentage (Vn) as a function of cooling speed indicator (CSIn) are tabulated and used to determine a target cycle time.