Patents by Inventor Sean X. Sun

Sean X. Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GROWTH AND SITE-SPECIFIC ORGANIZATION OF MICRO-SCALE BIMOLECULAR DEVICES ON LIVING CELLS
    Publication number: 20230304992
    Abstract: Described are conjugates of nucleic acid nanotubes and cells by linking the nanotubes to a cell surface moiety. Devices, kits, systems, and methods comprising the nanotube cell conjugates are also described.
    Type: Application
    Filed: June 29, 2021
    Publication date: September 28, 2023
    Inventors: Rebecca B. Schulman, Sisi Jia, Siew Cheng Phua, Yuta Nihongaki, Yizeng Li, Michael Pacella, Yi Li, Abdul Majeed Mohammed, Sean X. Sun, Takanari Inoue
  • A NOVEL, ORGAN-ON-A-CHIP DEVICE FOR ASSESSING TRANS-EPITHELIAL TRANSPORT, AND USES THEREOF
    Publication number: 20220265176
    Abstract: Embodiments of the invention relate to devices and methods for measuring a fluidic flux and a fluidic pressure through a tissue layer. Related devices include: a first micro-patterned layer; a second micro-patterned layer attached to the first micro-patterned layer; a porous membrane disposed between the first micro-patterned layer and the second micro-patterned layer, where the second micro-patterned layer and the porous membrane together define an upper channel across an upper surface of the tissue layer while in use; where the first micro-patterned layer and the porous membrane together define a lower channel across a lower surface of the tissue layer while in use; and a pressure monitor arranged in operative communication with the upper and lower channels. The pressure monitor is configured to measure a fluidic pressure in the upper channel and a fluidic pressure in the lower channel.
    Type: Application
    Filed: July 8, 2020
    Publication date: August 25, 2022
    Applicant: The Johns Hopkins University
    Inventors: Sean X. Sun, Mohammad lKbal Choudhury
  • Magnetic tweezers method to measure single molecule torque
    Patent number: 8350564
    Abstract: A system and a method for determining the torque imposed on a filament, such as a single DNA strand or macromolecule, using a magnetic probe and an imaging device.
    Type: Grant
    Filed: March 9, 2010
    Date of Patent: January 8, 2013
    Assignee: The Johns Hopkins University
    Inventors: Alfredo A. Celedon, Sean X. Sun, Gregory Bowman, Denis Wirtz, Peter Searson
  • MAGNETIC TWEEZERS METHOD TO MEASURE SINGLE MOLECULE TORQUE
    Publication number: 20100253328
    Abstract: A system and a method for determining the torque imposed on a filament, such as a single DNA strand or macromolecule, using a magnetic probe and an imaging device.
    Type: Application
    Filed: March 9, 2010
    Publication date: October 7, 2010
    Applicant: Johns Hopkins University
    Inventors: Alfredo A. Celedon, Sean X. Sun, Gregory Bowman, Denis Wirtz, Peter Searson