Patents by Inventor Sebastián Cerdan Garcia-Esteller

Sebastián Cerdan Garcia-Esteller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Superparamagnetic nanoparticles as a contrast agent for magnetic resonance imaging (MRI) of magnetic susceptibility (T2*)
    Patent number: 10987436
    Abstract: The invention relates to the use of biocompatible superparamagnetic nanoparticles comprising an inorganic core and a coating including an electrically charged polymer, and having low tissue and vascular adhesion, for use as contrast agents in magnetic resonance imaging (MRI). The aforementioned nanoparticles have novel pharmacokinetic and relaxability T2* properties, with high potential for use in in vivo tissue imaging and tumour perfusion strategies based on parameter T2*.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: April 27, 2021
    Assignee: SOLUCIONES NANOTECNOLÓGICAS, S.L.
    Inventors: Sebastián Cerdan Garcia-Esteller, Daniel Calle Hernández, Fernando Moreno Egea
  • SUPERPARAMAGNETIC NANOPARTICLES AS A CONTRAST AGENT FOR MAGNETIC RESONANCE IMAGING (MRI) OF MAGNETIC SUSCEPTIBILITY (T2*)
    Publication number: 20150217003
    Abstract: The invention relates to the use of biocompatible superparamagnetic nanoparticles comprising an inorganic core and a coating including an electrically charged polymer, and having low tissue and vascular adhesion, for use as contrast agents in magnetic resonance imaging (MRI). The aforementioned nanoparticles have novel pharmacokinetic and relaxability T2* properties, with high potential for use in in vivo tissue imaging and tumour perfusion strategies based on parameter T2*.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 6, 2015
    Inventors: Sebastián Cerdan Garcia-Esteller, Daniel Calle Hernández, Fernando Moreno Egea
  • Method of obtaining extracellular and intracellular pH images and spectra by magnetic resonance using extrinsic indicators containing 1H or 19F
    Patent number: 6596258
    Abstract: The present invention refers to the use of a selection of imidazole compounds in a method of obtaining extracellular or intracellular pH images in biological systems, by magnetic resonance, consisting of administering the imidazole compound to said biological system and acquiring a pH image through magnetic resonance measurements, and said method selected from the group consisting of proton magnetic resonance chemical shift imaging (1H CSI), proton magnetic resonance spectroscopic imaging (1H MRSI), fluorine magnetic resonance chemical shift imaging (19F CSI), fluorine magnetic resonance spectroscopic imaging (19F MRSI), and combinations thereof.
    Type: Grant
    Filed: June 7, 2000
    Date of Patent: July 22, 2003
    Assignee: Universidad Nacional de Educacion a Distancia
    Inventors: Paloma Ballesteros García, Ma Soledad Gil González, Paula Zaderenco Partida, Sebastián Cerdán García-Esteller, José Álvarez Pérez, J. Robert Gillies, Raghunand Natarajan, Robert Van Sluis, Zaver Bhujwala