Patents by Inventor Sebastian CAROTTA

Sebastian CAROTTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic compounds capable of activating STING
    Patent number: 12065427
    Abstract: The present invention relates to heterocyclic compounds of formula (I) capable of activating STING (Stimulator of Interferon Genes).
    Type: Grant
    Filed: April 27, 2022
    Date of Patent: August 20, 2024
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Sebastian Carotta, Georg Dahmann, Cédrickx Godbout, Sandra Ruth Handschuh, Herbert Nar, Thorsten Oost, Ulrich Reiser, Matthias Treu
  • HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING
    Publication number: 20240270718
    Abstract: The present invention relates to heterocyclic compounds of formula (I) capable of activating STING (Stimulator of Interferon Genes).
    Type: Application
    Filed: March 6, 2024
    Publication date: August 15, 2024
    Inventors: Sebastian CAROTTA, Georg DAHMANN, Cédrickx GODBOUT, Sandra Ruth HANDSCHUH, Herbert NAR, Thorsten OOST, Ulrich REISER, Matthias TREU
  • HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING
    Publication number: 20240174642
    Abstract: The present invention relates to compounds of formula (I) which are capable of activating STING (Stimulator of Interferon Genes). The present invention further relates to pharmaceutical compositions comprising at least a compound of formula (I), as well as the use of these compounds or the pharmaceutical compositions as a medicament, e.g., for treating canine or feline cancer, or as vaccine adjuvants.
    Type: Application
    Filed: October 24, 2023
    Publication date: May 30, 2024
    Inventors: Keith Andrew Newton GRAHAM, Sebastian CAROTTA, Georg DAHMANN, Cédrickx GODBOUT, Sandra Ruth HANDSCHUH, Herbert NAR, Thorsten OOST, Ulrich REISER, Esther SCHMIDT, Matthias TREU
  • HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING
    Publication number: 20240174641
    Abstract: The present invention relates to compounds of formula (I) which are capable of activating STING (Stimulator of Interferon Genes). The present invention further relates to pharmaceutical compositions comprising at least a compound of formula (I), as well as the use of these compounds or the pharmaceutical compositions as a medicament, e.g., for treating canine or feline cancer, or as vaccine adjuvants.
    Type: Application
    Filed: October 24, 2023
    Publication date: May 30, 2024
    Inventors: Keith Andrew Newton GRAHAM, Sebastian CAROTTA, Georg DAHMANN, Cédrickx GODBOUT, Sandra Ruth HANDSCHUH, Timo MISSEL, Herbert NAR, Thorsten OOST, Ulrich REISER, Esther SCHMIDT, Matthias TREU
  • HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING
    Publication number: 20240166629
    Abstract: The present invention relates to heterocyclic compounds of formula (I) capable of activating STING (Stimulator of Interferon Genes).
    Type: Application
    Filed: October 24, 2023
    Publication date: May 23, 2024
    Inventors: Ulrich REISER, Sebastian CAROTTA, Georg DAHMANN, Cédrickx GODBOUT, Sandra Ruth HANDSCHUH, Herbert NAR, Thorsten OOST, Matthias TREU
  • HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING
    Publication number: 20220388986
    Abstract: The present invention relates to heterocyclic compounds of formula (I) capable of activating STING (Stimulator of Interferon Genes).
    Type: Application
    Filed: April 27, 2022
    Publication date: December 8, 2022
    Inventors: Sebastian CAROTTA, Georg DAHMANN, Cédrickx GODBOUT, Sandra Ruth HANDSCHUH, Herbert NAR, Thorsten OOST, Ulrich REISER, Matthias TREU
  • [1,6]naphthyridine compounds and derivatives as CDK8/CDK19 inhibitors
    Patent number: 11261184
    Abstract: The present invention encompasses compounds of formula (I) wherein the groups R1 to R5, A and q have the meanings given in the claims and specification, their use as inhibitors of CDK8/19, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
    Type: Grant
    Filed: October 1, 2018
    Date of Patent: March 1, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Harald Engelhardt, Heribert Arnhof, Sebastian Carotta, Marco Hofmann, Marc Kerenyi, Dirk Scharn
  • Phenylpyrazolylacetamide compounds and derivatives as CDK8/CDK19 inhibitors
    Patent number: 11213520
    Abstract: The present invention encompasses compounds of formula (I) wherein the groups R2 to R5, A, X and q have the meanings given in the claims and specification, their use as inhibitors of CDK8/19, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: January 4, 2022
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Harald Engelhardt, Heribert Arnhof, Sebastian Carotta, Marco Hans Hofmann, Marc Kerenyi, Dirk Scharn
  • NEW [1,6]NAPHTHYRIDINE COMPOUNDS AND DERIVATIVES AS CDK8/CDK19 INHIBITORS
    Publication number: 20200291020
    Abstract: The present invention encompasses compounds of formula (I) wherein the groups R1 to R5, A and q have the meanings given in the claims and specification, their use as inhibitors of CDK8/19, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
    Type: Application
    Filed: October 1, 2018
    Publication date: September 17, 2020
    Inventors: Harald ENGELHARDT, Heribert ARNHOF, Sebastian CAROTTA, Marco HOFMANN, Marc KERENYI, Dirk SCHARN
  • Cyclic dinucleotide compounds
    Patent number: 10537590
    Abstract: The present invention relates to compounds of general formula I, wherein the groups R1, R2 and R3 are defined as in claim 1, which have valuable pharmacological properties, particularly are modulators of STING.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: January 21, 2020
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thorsten Oost, Sebastian Carotta, Martin Fleck
  • NEW PHENYLPYRAZOLYLACETAMIDE COMPOUNDS AND DERIVATIVES AS CDK8/CDK19 INHIBITORS
    Publication number: 20190290637
    Abstract: The present invention encompasses compounds of formula (I) wherein the groups R2 to R5, A, X and q have the meanings given in the claims and specification, their use as inhibitors of CDK8/19, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
    Type: Application
    Filed: May 19, 2017
    Publication date: September 26, 2019
    Inventors: Harald ENGELHARDT, Heribert ARNHOF, Sebastian CAROTTA, Marco Hans HOFMANN, Marc KERENYI, Dirk SCHARN
  • Modified cyclic dinucleotide compounds
    Patent number: 10392419
    Abstract: Compounds of formula (I) wherein Base1 and Base2 are defined as in claim 1 are modulators of STING.
    Type: Grant
    Filed: March 20, 2018
    Date of Patent: August 27, 2019
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Thorsten Oost, Martin Fleck, Christian Andreas Kuttruff, Sebastian Carotta
  • MODIFIED CYCLIC DINUCLEOTIDE COMPOUNDS
    Publication number: 20180273578
    Abstract: Compounds of formula (I) wherein Base1 and Base2 are defined as in claim 1 are modulators of STING.
    Type: Application
    Filed: March 20, 2018
    Publication date: September 27, 2018
    Inventors: Thorsten OOST, Martin FLECK, Christian Andreas KUTTRUFF, Sebastian CAROTTA
  • CYCLIC DINUCLEOTIDE COMPOUNDS
    Publication number: 20180092937
    Abstract: The present invention relates to compounds of general formula I, wherein the groups R1, R2 and R3 are defined as in claim 1, which have valuable pharmacological properties, particularly are modulators of STING.
    Type: Application
    Filed: September 27, 2017
    Publication date: April 5, 2018
    Inventors: Thorsten OOST, Sebastian CAROTTA, Martin FLECK