Patents by Inventor Sebastian Dominik Pawlak

Sebastian Dominik Pawlak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anticancer fusion protein comprising trail and a growth factor receptor inhibitor
    Patent number: 9175059
    Abstract: A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an anti-angiogenic effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
    Type: Grant
    Filed: January 5, 2012
    Date of Patent: November 3, 2015
    Assignee: Adamed Sp. z o.o.
    Inventors: Jerzy Szczepan Pieczykolan, Sebastian Dominik Pawlak, Bartlomiej Maciej Żerek, Piotr Kamil Rózga
  • ANTICANCER FUSION PROTEIN
    Publication number: 20140377216
    Abstract: A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity, preferably 85% identity and ending with the amino acid hTRAIL281; and at least one domain (b) which is a sequence of a cytolytic effector peptide forming pores in the cell membrane, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
    Type: Application
    Filed: December 22, 2012
    Publication date: December 25, 2014
    Inventors: Jerzy Szczepan Pieczykolan, Sebastian Dominik Pawlak, Bartlomiej Maciej Zerek, Piotr Kamil Rozga
  • ANTICANCER FUSION PROTEIN
    Publication number: 20140031283
    Abstract: A fusion protein comprising domain (a) which is the functional fragment of a hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and at least one domain (b) which is the sequence of an effector peptide having anti-proliferative activity against tumour cells, wherein the sequence of domain (b) is attached at the C-terminus or at the N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
    Type: Application
    Filed: April 19, 2012
    Publication date: January 30, 2014
    Applicant: ADAMED SP. Z O.O.
    Inventors: Jerzy Szczepan Pieczykolan, Sebastian Dominik Pawlak, Barttomie Maciej Aerek, Piotr Kamil Rózga, Urszula Marta Szawlowska
  • ANTICANCER FUSION PROTEIN
    Publication number: 20130288963
    Abstract: A fusion protein comprising domain (a) which is a functional fragment of hTRAIL protein sequence, which fragment begins with an amino acid at a position not lower than hTRAIL95, or a homolog of said functional fragment having at least 70% sequence identity; and domain (b) which is a sequence of an anti-angiogenic effector peptide, wherein the sequence of domain (b) is attached at the C-terminus or N-terminus of domain (a). The fusion protein can be used for the treatment of cancer diseases.
    Type: Application
    Filed: January 5, 2012
    Publication date: October 31, 2013
    Applicant: ADAMED SP. Z O.O.
    Inventors: Jerzy Szczepan Pieczykolan, Sebastian Dominik Pawlak, Bartlomiej Maciej Zerek, Piotr Kamil Rózga