Patents by Inventor Sebastian Gromminger

Sebastian Gromminger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Detection of DNA that originates from a specific cell-type and related methods
    Patent number: 11965207
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: April 23, 2024
    Assignee: EUROFINS LIFECODEXX GMBH
    Inventors: Sebastian Grömminger, Wera Hofmann, Hamed Said, Matthias Sachse
  • Multiplex detection of DNA that originates from a specific cell-type
    Patent number: 11773443
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Grant
    Filed: June 11, 2018
    Date of Patent: October 3, 2023
    Assignee: EUROFINS LIFECODEXX GMBH
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • DETECTION OF DNA THAT ORIGINATES FROM A SPECIFIC CELL-TYPE AND RELATED METHODS
    Publication number: 20200407793
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Application
    Filed: July 28, 2020
    Publication date: December 31, 2020
    Inventors: Sebastian Grömminger, Wera Hofmann, Hamed Said, Matthias Sachse
  • Detection of DNA that originates from a specific cell-type and related methods
    Patent number: 10801067
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: October 13, 2020
    Assignee: Eurofins LifeCodexx GmbH
    Inventors: Sebastian Grömminger, Wera Hofmann, Hamed Said, Matthias Sachse
  • MULTIPLEX DETECTION OF DNA THAT ORIGINATES FROM A SPECIFIC CELL-TYPE
    Publication number: 20180334715
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Application
    Filed: June 11, 2018
    Publication date: November 22, 2018
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • Multiplex detection of DNA that originates from a specific cell-type
    Patent number: 10017818
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on different methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumor.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: July 10, 2018
    Assignee: LifeCodexx AG
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • Detection of DNA that originates from a specific cell-type
    Patent number: 9822412
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumor.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: November 21, 2017
    Assignee: LifeCodexx AG
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • Multiplex detection of DNA that originates from a specific cell-type
    Patent number: 9822413
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumor.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: November 21, 2017
    Assignee: LifeCodexx AG
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • DETECTION OF DNA THAT ORIGINATES FROM A SPECIFIC CELL-TYPE AND RELATED METHODS
    Publication number: 20170314073
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Application
    Filed: May 8, 2015
    Publication date: November 2, 2017
    Inventors: Sebastian Grömminger, Wera Hofmann, Hamed Said, Matthias Sachse
  • MULTIPLEX DETECTION OF DNA THAT ORIGINATES FROM A SPECIFIC CELL-TYPE
    Publication number: 20150322512
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on different methylation, at certain regions of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Application
    Filed: May 8, 2015
    Publication date: November 12, 2015
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • DETECTION OF DNA THAT ORIGINATES FROM A SPECIFIC CELL-TYPE
    Publication number: 20150322511
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Application
    Filed: May 8, 2015
    Publication date: November 12, 2015
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said
  • MULTIPLEX DETECTION OF DNA THAT ORIGINATES FROM A SPECIFIC CELL-TYPE
    Publication number: 20150322513
    Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA thst originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.
    Type: Application
    Filed: May 8, 2015
    Publication date: November 12, 2015
    Inventors: Sebastian Gromminger, Wera Hofmann, Hamed Said