Patents by Inventor Sebastian Hartmut Springer

Sebastian Hartmut Springer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing an examination reagent and kit for analysing a T-cell frequency
    Patent number: 11698375
    Abstract: A method for producing an examination reagent includes adding a helper ligand to a receptor protein which is unfolded in an initial solution so as to provide a pre-solution of the examination reagent with a receptor protein which is folded. The receptor protein which is folded comprises a bonded helper ligand which can be exchanged with an examination peptide.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: July 11, 2023
    Assignee: CONSTRUCTOR UNIVERSITY BREMEN GGMBH
    Inventors: Sebastian Hartmut Springer, Sunil Kumar Saini
  • METHOD AND KIT FOR DETECTING T-CELLS
    Publication number: 20220050104
    Abstract: A method for detecting T cells includes a first step of bringing a plurality of different antigenic peptides into contact with peptide-free MHC molecules which are arranged in an immobilized manner on a substrate in an array so that the plurality of different antigenic peptides bind to the peptide-free MHC molecules so as to form peptide-loaded MHC molecules, a second step of bringing a sample comprising the T cells into contact with the peptide-loaded MHC molecules on the substrate, and a third step of detecting the binding of the T cells to the peptide-loaded MHC molecules on the substrate.
    Type: Application
    Filed: November 19, 2019
    Publication date: February 17, 2022
    Applicant: JACOBS UNIVERSITY BREMEN GGMBH
    Inventors: CINDY DIRSCHERL, SEBASTIAN HARTMUT SPRINGER
  • METHOD FOR PRODUCING AN EXAMINATION REAGENT AND KIT FOR ANALYSING A T-CELL FREQUENCY
    Publication number: 20190331681
    Abstract: A method for producing an examination reagent includes adding a helper ligand to a receptor protein which is unfolded in an initial solution so as to provide a pre-solution of the examination reagent with a receptor protein which is folded. The receptor protein which is folded comprises a bonded helper ligand which can be exchanged with an examination peptide.
    Type: Application
    Filed: July 1, 2019
    Publication date: October 31, 2019
    Applicant: JACOBS UNIVERSITY BREMEN GGMBH
    Inventors: SEBASTIAN HARTMUT SPRINGER, SUNIL KUMAR SAINI
  • Method for producing an examination reagent and kit for analysing a T-cell frequency
    Patent number: 10386367
    Abstract: A method for producing an examination reagent includes adding a helper ligand to an unfolded receptor protein in an initial solution so as to provide a pre-solution of the examination reagent with a folded receptor protein. The folded receptor protein comprises a bonded helper ligand which can be exchanged with an examination peptide.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: August 20, 2019
    Assignee: JACOBS UNIVERSITY BREMEN GGMBH
    Inventors: Sebastian Hartmut Springer, Sunil Kumar Saini