Patents by Inventor Sebastian Himbert

Sebastian Himbert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230390200
    Abstract: Described herein is a hybrid biological membrane comprising an endogenous bilayer doped with one or more synthetic lipid molecules. Also described herein is a method of preparing a hybrid biological membrane, the method comprising doping an endogenous bilayer with one or more synthetic lipid molecules.
    Type: Application
    Filed: August 21, 2023
    Publication date: December 7, 2023
    Inventors: Maikel C. Rheinstädter, Sebastian Himbert, Matthew Blacker
  • Patent number: 11771650
    Abstract: Described herein is a hybrid biological membrane comprising an endogenous bilayer doped with one or more synthetic lipid molecules. Also described herein is a method of preparing a hybrid biological membrane, the method comprising doping an endogenous bilayer with one or more synthetic lipid molecules.
    Type: Grant
    Filed: December 18, 2020
    Date of Patent: October 3, 2023
    Assignee: McMaster University
    Inventors: Maikel C. Rheinstädter, Sebastian Himbert, Matthew Blacker
  • Publication number: 20230158507
    Abstract: Provided herein is a biosensor suitable for use in measuring membrane fluidity or membrane permeability. The biosensor is formed of a solid substrate having a lipid bilayer compatible surface and a multi-lamellar lipid membrane structure localized on the lipid bilayer compatible surface. The multi-lamellar lipid membrane structure can be derived from a biological cell further comprising one or more synthetic lipids. An electrode forming all or part of the lipid bilayer compatible surface may be used to detect disruptions in the lipid membrane structure and hemolytic activity in a test sample.
    Type: Application
    Filed: January 17, 2023
    Publication date: May 25, 2023
    Inventors: Sebastian Himbert, Maikel Rheinstadter
  • Patent number: 11577248
    Abstract: A biosensor detector device is disclosed suitable for use in measuring membrane fluidity or membrane permeability. The biosensor detector device is formed of a solid substrate having a lipid bilayer compatible surface, a multi-lamellar lipid membrane structure derived from a biological cell and localized on the lipid bilayer compatible surface, an aqueous layer interposed between each lipid bilayer of the multi-lamellar lipid membrane structure. The biological membrane is derived from human red blood cells and localized on the lipid bilayer compatible surface. An electrode forming all or part of the lipid bilayer compatible surface may be used to detect disruptions in the multi-lamellar lipid membrane structure and hemolytic activity in a test sample.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: February 14, 2023
    Assignee: McMaster University
    Inventors: Maikel Rheinstadter, Sebastian Himbert, Richard Alsop, Jose Moran-Mirabal, Sokunthearath Saem, Dawn Bowdish
  • Publication number: 20210205218
    Abstract: Described herein is a hybrid biological membrane comprising an endogenous bilayer doped with one or more synthetic lipid molecules. Also described herein is a method of preparing a hybrid biological membrane, the method comprising doping an endogenous bilayer with one or more synthetic lipid molecules.
    Type: Application
    Filed: December 18, 2020
    Publication date: July 8, 2021
    Inventors: Maikel C. Rheinstädter, Sebastian Himbert, Matthew Blacker
  • Publication number: 20190195867
    Abstract: A biosensor detector device is disclosed suitable for use in measuring membrane fluidity or membrane permeability. The biosensor detector device is formed of a solid substrate having a lipid bilayer compatible surface, a multi-lamellar lipid membrane structure derived from a biological cell and localized on the lipid bilayer compatible surface, an aqueous layer interposed between each lipid bilayer of the multi-lamellar lipid membrane structure. The biological membrane is derived from human red blood cells and localized on the lipid bilayer compatible surface. An electrode forming all or part of the lipid bilayer compatible surface may be used to detect disruptions in the multi-lamellar lipid membrane structure and hemolytic activity in a test sample.
    Type: Application
    Filed: December 21, 2018
    Publication date: June 27, 2019
    Inventors: Maikel Rheinstadter, Sebastian Himbert, Richard Alsop, Jose Moran-Mirabal, Sokunthearath Saem, Dawn Bowdish