Abstract: Disclosed is biomanufacturing apparatus 1 comprising a housing 20 including top 22 and bottom 24 faces which allow stacking of plural housings, an access door 25 at a front side of the housing, a substantially enclosed bioreactor chamber 30 inside the housing accessible via the door, and a further substantially enclosed region 36 inside the housing containing electrical parts and/or electronic control components, the chamber 30 including: a tray 40 for supporting a bioreactor, a tray support 45 including a mechanism 44,47 for rocking the tray in use; at least a fluid handling portion 48,49 of at least one fluid pump device 54/58; and at least one connection 43 for connecting to a conduit and/or path for carrying fluids, gas and/or electricity.

Abstract: A method is described for preparing a catalyst including the steps of: (i) impregnating a calcined support comprising a metal aluminate with a solution of nickel acetate at a temperature ?40° C. and drying the impregnated support, (ii) calcining the dried impregnated support, to form nickel oxide on the surface of the support and (iii) optionally repeating steps (i) and (ii) on the nickel oxide coated support. The method provides an eggshell catalyst in which the metal oxide is concentrated in an outer layer on the support.

Abstract: Disclosed is biomanufacturing apparatus (1) comprising a housing (20), a substantially enclosed bioreactor chamber (30) inside the housing and a further substantially enclosed region (36) inside the housing containing electrical parts and/or electronic control components, the chamber (30) including: a tray (40) for supporting a bioreactor, a tray support (45) including a mechanism (44,47) for rocking the tray in use the tray (40) including a heater (42) for contacting a bioreactor and heating the same, and the apparatus further comprising secondary heating (53) for heating air surrounding the tray.

Abstract: Disclosed is biomanufacturing apparatus 1 comprising a housing 20 including top 22 and bottom 24 faces which allow stacking of plural housings, an access door 25 at a front side of the housing, a substantially enclosed bioreactor chamber 30 inside the housing accessible via the door, and a further substantially enclosed region 36 inside the housing containing electrical parts and/or electronic control components, the chamber 30 including: a tray 40 for supporting a bioreactor, a tray support 45 including a mechanism 44,47 for rocking the tray in use; the tray support further including a load cell (41) to determine changes in the mass load on the tray.

Abstract: Disclosed is a biomanufacturing apparatus (1) comprising a housing (20) including top (22) and bottom (24) faces which allow stacking of plural housings, an access door (25) at a front side of the housing, a substantially enclosed bioreactor chamber (30) inside the housing accessible via the door, and a further substantially enclosed region (36) inside the housing containing electrical parts and/or electronic control components, the chamber (30) including: a tray (40/240) for supporting a bioreactor, a tray support (45/245) including a mechanism (44,47/244,247) for rocking the tray in use; the tray having complementary formations allowing movement of tray relative to the tray support toward the front side to allow more convenient access to the bioreactor.

Abstract: The present invention provides a device and method for sampling from a cell culture bioreactor. The invention is useful where it is required to determine the cell count, provide a sample for off-line analyses or remove a sample while at the same time retain sterility of the sample for quality control (QC) assessment. The device of the invention allows for facile aseptic sampling at one or more instances in time during a cell expansion in a bioreactor.

Abstract: The present invention relates to a novel bioreactor system for cell cultivation. More specifically, the invention relates to a compact bioreactor system which has several integrated functions and enables small scale static culture as well as scale-up rocking culture in the same bioreactor. The bioreactor system comprises tray for positioning of a cell culture bag having adjustable volume, a lid covering the cell culture bag and provided with heating function, an integrated perfusion unit, an integrated cell loading unit, and an integrated unit for automatic cell culture sampling, wherein the bioreactor system is controlled by a single control unit. The invention also relates to a method of cell culture using the bioreactor system for culture of therapeutic cells.

Abstract: A method is described for preparing a catalyst including the steps of: (i) impregnating a calcined support comprising a metal aluminate with a solution of nickel acetate at a temperature ?40° C. and drying the impregnated support, (ii) calcining the dried impregnated support, to form nickel oxide on the surface of the support and (iii) optionally repeating steps (i) and (ii) on the nickel oxide coated support. The method provides an eggshell catalyst in which the metal oxide is concentrated in an outer layer on the support.

Abstract: A method is described for preparing a catalyst including the steps of: (i) impregnating a calcined support comprising a metal aluminate with a solution of nickel acetate at a temperature ?40° C. and drying the impregnated support, (ii) calcining the dried impregnated support, to form nickel oxide on the surface of the support and (iii) optionally repeating steps (i) and (ii) on the nickel oxide coated support. The method provides an eggshell catalyst in which the metal oxide is concentrated in an outer layer on the support.

Abstract: A method is described for preparing a catalyst comprising including the steps of: (i) impregnating a calcined support comprising a metal aluminate with a solution of nickel acetate at a temperature ?40° C. and drying the impregnated support, (ii) calcining the dried impregnated support, to form nickel oxide on the surface of the support and (iii) optionally repeating steps (i) and (ii) on the nickel oxide coated support. The method provides an eggshell catalyst in which the metal oxide is concentrated in an outer layer on the support.

Abstract: A novelty electronic device that audibly plays back prerecorded audience responses. Prerecorded sounds include laughter, applause, sorrow, surprise, disgust and cheers. Other sounds effects may include a tuba (wah, wah, wah) and/or cricket noises to simulate sound effects heard on various television sitcoms.

Abstract: A polarization mode dispersion (PMD) compensator for compensation of PMD in polarization bit interleaved (PBI) optical signals is disclosed. The control uses spectral analysis of components of the electrical output, particularly analysis of a spectral component having a frequency corresponding to the bit frequency of the two bit streams which form the bit interleaved signal. Minimising this spectral component results in alignment of the signal in the system at 45 degrees to the two principal axes. An apparatus for measuring PMD based on spectral analysis is also disclosed.

Abstract: Computational fluid dynamics modelling can be provided to customers using a network, so the customer only needs a network access device that includes client software, for example a Web browser. The computational fluid dynamics software is provided on a server computer also connected to the network. The customer logs on to the server computer, using the client software, and is offered a menu of several different categories of engineering problems from which he makes a selection. Specific details such as dimensions relevant to the selected category of problem are then requested through the client software, and are entered by the customer. The server computer models the specified problem, prepares results in an output form, and informs the customer by email. The results, which may include images showing the flow patterns, are provided to the customer over the network via the client software.

Abstract: The use of regularly repeated small sections of pattern in making a complete optical grating may generate unwanted effects, such as side lobes, as a result of the regular repetition of defects in the small sections. Methods are described for disrupting the regularity of the occurrence of such defects in a grating made of a plurality of sections, thereby minimizing the likelihood of the occurrence of unwanted side lobes, for example.

Abstract: A laundry bag has two flaps, one for directly overlying laundry and the second to overlie the first and close the bag. Side panels at right angles to the flaps also fold over laundry. The side and flaps join the body of the bag at a seam. This seam provides a natural fold for the sides and flaps to fold over the top of a hamper and hold the bag to the hamper. A band extends from the seam to stiffen the fold and reinforce the bag proximate the seam.