Abstract: Various systems and methods are presented regarding automatically controlling a position of a seat belt located onboard a vehicle, wherein the position is controlled in accordance with physiology of an occupant utilizing the seat belt. By adjusting the position of the seat belt in accordance with the occupant's physiology, the seat belt system can be configured to improve operation of the seat belt in restraining the occupant during vehicle deceleration. Position of the seat belt can be controlled by a guidance device comprising a loop through which the seatbelt is fed, with the loop being positioned along at least one axis of motion. A motor can be utilized to control positioning of the loop, wherein the motor can be controlled by a system configured to receive data from one or more sensors regarding any of the occupant's physiology, operation of the seat belt, position of the loop, and suchlike.

Abstract: Various systems and methods are presented regarding automatically controlling a position of a seat belt located onboard a vehicle, wherein the position is controlled in accordance with physiology of an occupant utilizing the seat belt. By adjusting the position of the seat belt in accordance with the occupant's physiology, the seat belt system can be configured to improve operation of the seat belt in restraining the occupant during vehicle deceleration. Position of the seat belt can be controlled by a guidance device comprising a positionable guide pin which changes alignment of the seatbelt. A motor can be utilized to control positioning of the pin, wherein the motor can be controlled by a system configured to receive data from one or more sensors regarding any of the occupant's physiology, operation of the seat belt, position of the pin, and suchlike.

Abstract: The present disclosure relates to a medicament delivery device sub-assembly having an injection needle assembly, a cartridge and a seal. The injection needle assembly has opposite distal and proximal ends, and has a retainer member configured to be connectable to a medicament container; a hub configured to be coaxially displaceable within the retainer member and provided with an injection needle having proximal and distal pointed ends; and a cap member interactively connected to both the hub and to the retainer member. A sealing member can be arranged between the cap member and the retainer member for preventing contamination of the injection needle before use. The seal seals a gap between the injection needle assembly and the cartridge. Methods of assembly are also described.

Abstract: Apparatus including tubing sets and methods of use are described for deliver a therapeutic medication to a patient, the apparatus comprising a controller and a sensor. The controller is configured to receive data from the sensor, and to start and stop delivery of the therapeutic medication to the patient in response to data received from the sensor. In addition, apparatus, systems and methods are disclosed, which are configured to deliver a therapeutic medication to a patient. The apparatus, system and methods comprise a reservoir, a patient interface, a tubing set, and a fluid pump, and the components are configured to provide a calibrated flow rate based upon specific characteristics of the therapeutic medications passing through and internal lumen of the tubing set.

Abstract: The present disclosure provides a method of assembling a medicament delivery device. The method includes providing a housing of the medicament delivery device, wherein the housing extends along a longitudinal axis between a proximal end and a distal end. The method also includes providing a power unit of the medicament delivery device, wherein the power unit comprises a plunger rod and a holder engaged with the plunger rod. The method also includes assembling the power unit into the housing. The method also includes providing a cap assembly extending along the longitudinal axis between a proximal end and a distal end. The method also includes connecting the cap assembly to either the plunger rod or the holder.

Abstract: An injection device with a feedback mechanism includes a housing for a medicament container having a stopper, a plunger rod for acting on the stopper, a button interactively connected to the plunger rod, an activation member having a flexible locking device releasably connected to the plunger rod, a drive force device, a locking member slidable between positions in which the locking member either completely or partially surrounds the flexible locking device, and a guide rod. Audible and tactile information that an injection has started is provided by the plunger rod's hitting the stopper.

Abstract: A needle having a needle body defining a first reference plane therethrough and a multi-beveled point including a primary bevel, two first middle bevels, two tip bevels. The primary bevel, the first middle bevels, and the tip bevels are located on a first face and, each of the first middle bevels is located between the primary bevel and one of the tip bevels. The primary bevel is provided on the cannula at a first angle of inclination with respect to the first reference plane and a first angle of rotation with respect to the first reference plane. The two first middle bevels are provided on the cannula at a second angle of inclination with respect to the first reference plane and a second angle of rotation with respect to the first reference plane. The two tip bevels are provided on the cannula at a third angle of inclination with respect to the first reference plane and a third angle of rotation with respect to the first reference plane.

Abstract: An injection device with a feedback mechanism includes a housing for a medicament container having a stopper, a plunger rod for acting on the stopper, a button interactively connected to the plunger rod, an activation member having a flexible locking device releasably connected to the plunger rod, a drive force device, a locking member slidable between positions in which the locking member either completely or partially surrounds the flexible locking device, and a guide rod. Audible and tactile information that an injection has started is provided by the plunger rod's hitting the stopper.

Abstract: An apparatus including tubing sets, a modular constraint assembly, and methods of use are described for deliver a therapeutic medication to a patient, the apparatus can have a controller and a sensor. The controller is configured to receive data from the sensor, and to start and stop delivery of the therapeutic medication to the patient in response to data received from the sensor. In addition, apparatus, systems and methods are disclosed, which are configured to deliver a therapeutic medication to a patient. The apparatus, system and methods use a reservoir, a patient interface, a tubing set, a modular constraint assembly connected to the tubing sets, and a fluid pump, and the components are configured to provide a calibrated flow rate based upon specific characteristics of the therapeutic medications passing through and internal lumen of the tubing set.

Abstract: An apparatus for use with tubing sets operatively connected to a medication deliver device, where the apparatus constricts fluid flow within the tubing are described for deliver a therapeutic medication to a patient, the apparatus operatively engages an outside surface of the tubing set causing compression of the tubing and reducing an inner diameter of the tubing.

Abstract: A medicament delivery device is presented having a housing with a proximal end and a distal end, a medicament container arranged within the housing, a biased delivery member cover associated with the housing and movable in relation to the housing, a biased plunger rod associated with the medicament container and movable in relation to the housing, a tubular rotator associated with both the delivery member cover and the biased plunger rod, and a cap assembly associated with the housing, wherein a gap is defined between the proximal end of the biased plunger rod and the stopper of the medicament container when the medicament delivery device is in an assembled state, and wherein the proximal end of the biased plunger rod is in contact with the stopper of the medicament container when the medicament delivery device is in a calibrated state.

Abstract: The present invention relates to a medicament delivery device comprising, a housing (10, 114) having a proximal and a distal end, a delivery member connected to the housing; a medicament container (84) operably arranged within the housing; a drive mechanism (102, 108) capable of acting on the medicament container (84) for priming and for expelling a dose of medicament. The invention is characterised in that the device further comprises - an activator mechanism configured to interact with the drive mechanism, such that a first interaction between the activator mechanism and the drive mechanism causes the container to move towards the delivery member wherein the container is primed and such that a subsequent second interaction between the activator mechanism and the drive mechanism causes a dose of medicament to be expelled through the delivery member. (FIG.

Abstract: The present invention relates to a medicament delivery device comprising, a housing (10, 114) having a proximal and a distal end, a delivery member connected to the housing; a medicament container (84) operably arranged within the housing; a drive mechanism (102, 108) capable of acting on the medicament container (84) for priming and for expelling a dose of medicament. The invention is characterised in that the device further comprises—an activator mechanism configured to interact with the drive mechanism, such that a first interaction between the activator mechanism and the drive mechanism causes the container to move towards the delivery member wherein the container is primed and such that a subsequent second interaction between the activator mechanism and the drive mechanism causes a dose of medicament to be expelled through the delivery member.

Abstract: A sub-assembly of a medicament delivery device is presented, where the sub-assembly includes a plunger rod that is biased, a main body arranged on the plunger rod, and a coupling member movable relative to the main body, where the main body includes a first locking element, the coupling member includes a second locking element, and where the first locking element and the second locking element are configured to be releasably engaged with each other such that the coupling member is prevented from moving relative to the main body.

Abstract: An apparatus including tubing sets, a modular constraint assembly, and methods of use are described for deliver a therapeutic medication to a patient, the apparatus can have a controller and a sensor. The controller is configured to receive data from the sensor, and to start and stop delivery of the therapeutic medication to the patient in response to data received from the sensor. In addition, apparatus, systems and methods are disclosed, which are configured to deliver a therapeutic medication to a patient. The apparatus, system and methods use a reservoir, a patient interface, a tubing set, a modular constraint assembly connected to the tubing sets, and a fluid pump, and the components are configured to provide a calibrated flow rate based upon specific characteristics of the therapeutic medications passing through and internal lumen of the tubing set.

Abstract: A sub-assembly of a medicament delivery device is presented, where the sub-assembly includes a plunger rod that is biased, a main body arranged on the plunger rod, and a coupling member movable relative to the main body, where the main body includes a first locking element, the coupling member includes a second locking element, and where the first locking element and the second locking element are configured to be releasably engaged with each other such that the coupling member is prevented from moving relative to the main body.

Abstract: A container holder assembly for a medicament delivery device is provided having a container holder and a needle assembly, where the container holder has a distal tubular body for receiving a multi-chamber container therein, the distal tubular body comprising a distal body engaging structure on an external surface configured to movably engage an actuator device of the medicament delivery device in order to releasably connect the container holder to the actuator device, and a proximal tubular part having a proximal body engaging structure connected to the needle assembly, where the needle assembly has a hub having an injection needle with a distal needle end and a proximal needle end, the distal needle end being isolated from the multi-chamber container when the multi-chamber container is received in the distal tubular body. A medicament delivery device having a container holder assembly is also provided.

Abstract: A medicament delivery device is presented having a housing with a proximal end and a distal end, a medicament container arranged within the housing, a biased delivery member cover associated with the housing and movable in relation to the housing, a biased plunger rod associated with the medicament container and movable in relation to the housing, a tubular rotator associated with both the delivery member cover and the biased plunger rod, and a cap assembly associated with the housing, wherein a gap is defined between the proximal end of the biased plunger rod and the stopper of the medicament container when the medicament delivery device is in an assembled state, and wherein the proximal end of the biased plunger rod is in contact with the stopper of the medicament container when the medicament delivery device is in a calibrated state.

Abstract: The invention relates to an air cleaner housing (200) for an air filter for an internal combustion engine in a vehicle, the air cleaner housing (200) being adapted for attachment to an outer cover (100) of said internal combustion engine (100), and comprising an inlet (201) for receiving unfiltered air and an outlet (202) for outputting filtered air. The air cleaner housing (200) comprises at least one slide member (210) configured to be slidably arranged to a corresponding guide member (110) of said outer cover (100), such that, when said slide member (210) is in connection with said guide member (110), said air cleaner housing (200) is supported by said guide member (110), and said air cleaner housing (200) is slidably movable at least along said guide member (110); and a fixation member (220) configured to secure the housing (200) to the outer cover (100) in a fixed position along said guide member (110). The invention also relates to an air cleaner housing arrangement, a method, and a vehicle.

Abstract: The invention relates to an air cleaner housing (200) for an air filter for an internal combustion engine in a vehicle, the air cleaner housing (200) being adapted for attachment to an outer cover (100) of said internal combustion engine (100), and comprising an inlet (201) for receiving unfiltered air and an outlet (202) for outputting filtered air. The air cleaner housing (200) comprises at least one slide member (210) configured to be slidably arranged to a corresponding guide member (110) of said outer cover (100), such that, when said slide member (210) is in connection with said guide member (110), said air cleaner housing (200) is supported by said guide member (110), and said air cleaner housing (200) is slidably movable at least along said guide member (110); and a fixation member (220) configured to secure the housing (200) to the outer cover (100) in a fixed position along said guide member (110). The invention also relates to an air cleaner housing arrangement, a method, and a vehicle.