Patents by Inventor Sebastian KELM

Sebastian KELM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARRAYS AND METHODS FOR IDENTIFYING BINDING SITES ON A PROTEIN
    Publication number: 20230176071
    Abstract: A method of identifying of amino-acid residues on a target protein that form a binding site of a molecule of interest. Such method relies on selection of relevant patches of solvent-accessible residues and testing of an array of mutated proteins for changes of binding properties. Such method is useful for determining binding sites (epitopes) of antibodies, ligands and related molecules.
    Type: Application
    Filed: May 6, 2021
    Publication date: June 8, 2023
    Inventors: Anastasios SPILIOTOPOULOS, David James MCMILLAN, Michael John Wright, Sebastian KELM, Xiaofeng LIU, Daniel John LIGHTWOOD
  • MULTI-DOMAIN PROTEINS WITH INCREASED NATIVE STATE COLLOIDAL STABILITY
    Publication number: 20210166780
    Abstract: The present invention provides a method for generation of multi-domain proteins, more particular antibodies, with an improved native state colloidal stability.
    Type: Application
    Filed: June 5, 2019
    Publication date: June 3, 2021
    Inventors: Ralph ADAMS, James HEADS, Sebastian KELM, Alastair David Griffiths LAWSON