Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Abstract: The disclosure relates to a thrust rod assembly for a linear actuator of an axle steering system of a vehicle, having at least one first rod and a spindle for converting a rotational movement of a drive device into a linear movement of the thrust rod assembly. The spindle has a spindle shoulder and, at a first axial end, a first connector shoulder for connection to the first rod. Between the spindle shoulder and the first connector shoulder, the spindle has a first receiving shoulder with a securing element received fixedly thereon for conjoint rotation for providing an anti-rotation safeguard of the thrust rod assembly. The securing element is held in the axial direction between the spindle shoulder and the first rod.

Abstract: One or more example embodiments relates to a method and a system for automatic creation of a multimedia radiological report on a patient, having: a medical information database which has written medical reports on patients; and a data processing unit which is configured: to create a multimedia report script based on the provided written medical report making use of a large language model; to provide selected data to which the written medical report on the patient and/or the created multimedia report script relate; to create a visual medical report on the patient based on the provided data and the created multimedia report script; and which is configured to combine automatically the created visual medical report and audio data for creating the multimedia radiological report on the patient.

Abstract: The disclosure relates to an actuator for an axle steering system of a vehicle that includes a push rod which is movable longitudinally within a housing, and a target holder for a target that is fastened releasably to the push rod. The target is designed to interact with a stationary sensor arrangement, and the target holder comprises a base part for receiving the target and at least one first clip contour, which is integrally formed on the base part, engages at least partially around the push rod and has a first clip arm and a second clip arm. The invention further relates to an axle steering system having such an actuator and to a vehicle having such an axle steering system.

Abstract: A screw connection is formed between steering components, namely a push rod and a fork, in particular of a rear axle steering system. By means of a screw screwed coaxially into one of the two steering components and inserted through an opening in the other steering component, an annular disc-shaped end face of the one steering component is pressed against a likewise annular disc-shaped face of the other steering component. Furthermore, cylindrical mating faces contacting one another are formed by the steering components. In at least one of the two steering components, a transition region is formed between the annular disc-shaped face and the cylindrical mating face, which has at least two different radii of curvature.

Abstract: Compounds according to general formula (I) act as inhibitors of NaV1.8 and can be used in the treatment of pain.

Abstract: A screw connection is formed between steering components, namely a push rod and a fork, in particular of a rear axle steering system. By means of a screw screwed coaxially into one of the two steering components and inserted through an opening in the other steering component, an annular disc-shaped end face of the one steering component is pressed against a likewise annular disc-shaped face of the other steering component. Furthermore, cylindrical mating faces contacting one another are formed by the steering components. In at least one of the two steering components, a transition region is formed between the annular disc-shaped face and the cylindrical mating face, which has at least two different radii of curvature.

Abstract: The present invention relates to compounds according to general formula (I) which act as inhibitors of NaV1.8 and can be used in the treatment of pain.

Abstract: A computer-implemented method and a corresponding apparatus are provided for the provision of a two-dimensional visualization image having a plurality of visualization pixels for the visualization of a three-dimensional object represented by volume data for a user. Context information for the visualization is obtained by the evaluation of natural language and is taken into account in the visualization. The natural language can be in the form of electronic documents, which are assigned or can be assigned to the visualization process. In addition, the natural language can be in the form of a speech input of a user, during or after the visualization.

Abstract: A method for supplying a three-dimensional model of an object represented by volume data, comprises: supplying the volume data; supplying an image synthesis algorithm, the image synthesis algorithm being configured for visualizing the three-dimensional object by mapping the volume data onto visualization pixels of a two-dimensional visualization image; ascertaining a parameter set for actuating the image synthesis algorithm, the parameter set being suitable for generating, with the image synthesis algorithm, a set of a plurality of different visualization images based on the volume data set; generating the set of the plurality of different visualization images by mapping the volume data, with the image synthesis algorithm, using the parameter set; calculating the 3D model based on the set of the plurality of different visualization images; and supplying the 3D model.

Abstract: An actuator of a steering system of a motor vehicle, having a connecting rod which is longitudinally movable in a housing along an actuating path between axial stops and which penetrates the housing and is connectable at one end to a toe link for the articulation of wheels, the stops of which are arranged axially one behind the other and face each other axially. The stops and a stopper interacting with the two stops are located inside the housing.

Abstract: The invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Abstract: The present invention relates to compounds according to general formula (I) which act as inhibitors of NaV1.8 and can be used in the treatment of pain.

Abstract: The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Abstract: The present invention relates to compounds according to general formula (I) which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Abstract: A method for the computer-aided processing of operating data relating to a technical system, wherein the operating data have been captured during operation of the technical system in a predefined operating interval and are stored as digital data in a memory is provided. A pair of first state variables and one or more second state variables with corresponding state values of the technical system at the particular operating time are extracted from the operating data by the method. A two-dimensional representation is generated on a display of a user interface by these state variables. Bar charts for different state ranges of the pairs of first state variables are generated in this representation on the basis of the evaluation of a threshold value criterion, wherein the bar charts represent, inter alia, how many states of the technical system within the particular state range can be classified as critical.

Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

Abstract: A computer-implemented method and a corresponding apparatus are provided for the provision of a two-dimensional visualization image having a plurality of visualization pixels for the visualization of a three-dimensional object represented by volume data for a user. Context information for the visualization is obtained by the evaluation of natural language and is taken into account in the visualization. The natural language can be in the form of electronic documents, which are assigned or can be assigned to the visualization process. In addition, the natural language can be in the form of a speech input of a user, during or after the visualization.

Abstract: The invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.