Abstract: The present invention relates to methods to detect an amount of DNA that originates from cells of a given type, where the sample comprising such DNA in admixture with DNA that does not originate from such cells. Such methods are based on differential methylation, at certain regions, of the DNA that originates from the given type of cells compared to the admixed DNA. Such methods have particular application in the detection, from a biological fluid from a pregnant female, of cell free DNA that originates from a foetus or the placenta of a foetus, or the detection, from a biological fluid from an individual, of cell free DNA that originates from cells of a tumour.

Abstract: A coiling system (1) and a method for coiling a hot rolled product, the system comprising:—a base assembly (3) comprising a base plate (6), a central drum (7) extending from the base plate along a vertical axis, and a receiving sleeve (8) arranged outside of said central drum,—a support structure (2) configured to support the base assembly and comprising a first drive mechanism configured to rotate the base assembly around the vertical axis,—a feeding device (4) configured to feed hot rolled product to the base assembly so as to form a coil (17), wherein the receiving sleeve is configured to receive a first end of the hot rolled product landing on said base plate so that a coil starts to form inside of said receiving sleeve and outside of said central drum, the base assembly being releasably connected to the first drive mechanism so that the base assembly, after coiling, may be removed from the support structure.

Abstract: An abrasive grain made from melted spherical corundum where the abrasive grain consists of a spherical corundum core, coated with an encircling layer of a binder and fine-grained abrasive solid particles.

Abstract: Titanium oxide-containing aluminum oxide particles are based on corundum melted in an electric arc furnace from calcined alumina. The particles may have an aluminum oxide content of less than 97.0% by weight, a titanium oxide content ranging from 1.3% by weight to 1.8% by weight, and a zirconium oxide content of ranging from 0.02% by weight to 0.1% by weight. The aluminum oxide particles may have an arithmetic mean compactness of less than 0.8.

Abstract: Titanium oxide-containing aluminum oxide particles are based on corundum melted in an electric arc furnace from calcined alumina. The particles may have an aluminum oxide content of less than 97.0% by weight, a titanium oxide content ranging from 1.3% by weight to 1.8% by weight, and a zirconium oxide content of ranging from 0.02% by weight to 0.1% by weight. The aluminum oxide particles may have an arithmetic mean compactness of less than 0.8.

Abstract: The present invention relates to polycrystalline Al2O3 bodies based on melted aluminum oxide having a mean crystallite size of the primary crystals between 20 ?m and 100 ?m and a closed macroporosity between 10% by volume and 30% by volume. The polycrystalline Al2O3 bodies may be obtained by tapping out and quenching a liquid aluminum oxide melt and simultaneous seeding of the pouring stream with seed crystals and can be used advantageously for the production of abrasive materials and refractory products.

Abstract: The present invention relates to polycrystalline Al2O3 bodies based on melted aluminum oxide having a mean crystallite size of the primary crystals between 20 ?m and 100 ?m and a closed macroporosity between 10% by volume and 30% by volume. The polycrystalline Al2O3 bodies may be obtained by tapping out and quenching a liquid aluminum oxide melt and simultaneous seeding of the pouring stream with seed crystals and can be used advantageously for the production of abrasive materials and refractory products.

Abstract: A method is provided for manufacturing spherical corundum grains having a bulk density between 1.5 kg/L and 2.5 kg/L, with aluminum oxide being melted in an electric arc furnace with the addition of 0.1 to 1% quartz sand, the melt being poured in a pouring quantity of less than 100 kg/min, and the pouring stream being blown using compressed air at a pressure between 3 to 10 bar.

Abstract: An embodiment consistent with the present invention is a high strength proppant comprising an electrofused pellet. In another embodiment, a high strength proppant comprises a substantially solid and substantially spherical pellet produced by electrofusion of at least one metal oxide. A method of making a proppant is also provided, with that method comprising melting at least one metal oxide in an electrical arc furnace, pouring the molten metal oxide to create a pour stream, and separating the pour stream to form at least one electrofused pellet. A method of fracturing subterranean formations is also provided, with that method comprising injecting a fluid containing at least one electrofused pellet.

Abstract: A method is provided for manufacturing spherical corundum grains having a bulk density between 1.5 kg/L and 2.5 kg/L, with aluminum oxide being melted in an electric arc furnace with the addition of 0.1 to 1% quartz sand, the melt being poured in a pouring quantity of less than 100 kg/min, and the pouring stream being blown using compressed air at a pressure between 3 to 10 bar.

Abstract: An abrasive grain made from melted spherical corundum where the abrasive grain consists of a spherical corundum core, coated with an encircling layer of a binder and fine-grained abrasive solid particles.

Abstract: An embodiment consistent with the present invention is a high strength proppant comprising an electrofused pellet. In another embodiment, a high strength proppant comprises a substantially solid and substantially spherical pellet produced by electrofusion of at least one metal oxide. A method of making a proppant is also provided, with that method comprising melting at least one metal oxide in an electrical arc furnace, pouring the molten metal oxide to create a pour stream, and separating the pour stream to form at least one electrofused pellet. A method of fracturing subterranean formations is also provided, with that method comprising injecting a fluid containing at least one electrofused pellet.