Patents by Inventor Sebastian Schaefer

Sebastian Schaefer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Decoy cytokine receptor
    Patent number: 12240889
    Abstract: An IL-11 binding receptor capable of binding to IL-11 and inhibiting IL-11 mediated signalling is disclosed. Also disclosed are compositions comprising the IL-11 binding receptor and methods using the IL-11 binding receptor.
    Type: Grant
    Filed: March 4, 2022
    Date of Patent: March 4, 2025
    Assignees: National University of Singapore, Singapore Health Services PTE LTD.
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • Treatment of kidney injury
    Patent number: 12234284
    Abstract: Methods of treating and preventing kidney injury through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: February 25, 2025
    Assignees: National University of Singapore, Singapore Health Services PTE LTD.
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Anissa Anindya Widjaja
  • TREATMENT OF FIBROSIS
    Publication number: 20240360211
    Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.
    Type: Application
    Filed: February 8, 2024
    Publication date: October 31, 2024
    Applicants: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • IL-11 ANTIBODIES
    Publication number: 20240270837
    Abstract: Provided are antigen-binding molecules capable of binding to IL-11, and methods of medical treatment and prophylaxis using the same.
    Type: Application
    Filed: March 1, 2024
    Publication date: August 15, 2024
    Applicants: Singapore Health Services PTE LTD, National University of Singapore, Boehringer Ingelheim International GmbH
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • IL-11 ANTIBODIES
    Publication number: 20240190953
    Abstract: Provided are antigen-binding molecules capable of binding to IL-11, and methods of medical treatment and prophylaxis using the same.
    Type: Application
    Filed: March 1, 2024
    Publication date: June 13, 2024
    Applicants: Singapore Health Services PTE LTD., National University of Singapore, Boehringer Ingelheim International GmbH
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • TREATMENT AND PREVENTION OF METABOLIC DISEASES
    Publication number: 20240156913
    Abstract: Methods of treating and preventing metabolic disease through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Application
    Filed: October 6, 2023
    Publication date: May 16, 2024
    Applicants: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Brijesh Kumar Singh, Anissa Widjaja
  • TREATMENT OF SMC MEDIATED DISEASE
    Publication number: 20240141004
    Abstract: Diagnosis, treatment and prophylaxis of diseases and conditions associated with smooth muscle cell (SMC) dysfunction are provided through the inhibition or IL-11-mediated signalling.
    Type: Application
    Filed: August 31, 2023
    Publication date: May 2, 2024
    Applicants: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Wei Wen Lim, Benjamin Wei Ming Ng
  • Treatment of fibrosis
    Patent number: 11939374
    Abstract: Aspects of the disclosure relate to the treatment, prevention or alleviation of conditions such as fibrosis in a subject. In some embodiments, the treatment, prevention or alleviation of fibrosis in a subject through the administration of an agent capable of inhibiting the action of Interleukin 11 (IL-11) is disclosed.
    Type: Grant
    Filed: December 2, 2020
    Date of Patent: March 26, 2024
    Assignees: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • Treatment and prevention of metabolic diseases
    Patent number: 11813311
    Abstract: Methods of treating and preventing metabolic disease through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: November 14, 2023
    Assignees: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Brijesh Kumar Singh, Anissa Widjaja
  • Treatment of SMC mediated disease
    Patent number: 11780898
    Abstract: Diagnosis, treatment and prophylaxis of diseases and conditions associated with smooth muscle cell (SMC) dysfunction are provided through the inhibition of IL-11-mediated signalling.
    Type: Grant
    Filed: October 12, 2018
    Date of Patent: October 10, 2023
    Assignees: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Wei Wen Lim, Benjamin Wei Ming Ng
  • TREATMENT AND PREVENTION OF DISEASE CAUSED BY TYPE IV COLLAGEN DYSFUNCTION
    Publication number: 20230212279
    Abstract: Methods of treating and preventing Alport syndrome through inhibiting interleukin 11 (EL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Application
    Filed: June 17, 2021
    Publication date: July 6, 2023
    Applicants: Singapore Health Services PTE, LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Anissa Anindya, Sebastian Schaefer
  • DEFLECTING SOUND WAVES AWAY FROM AN EAR OF A WEARER OF A SPORTS PROTECTIVE HELMET
    Publication number: 20220408867
    Abstract: Systems, apparatus, and methods for reducing the decibel levels of sound originated external to a sports protective helmet may minimize deleterious effects to the hearing of the individual wearing the sports protective helmet. Through use of a sound-deflecting apparatus that is coupled to an interior surface or to an exterior surface of the sports protective helmet proximate an ear hole, decibel volumes may be constructively reduced by deflecting high frequency sound waves while allowing low frequency sound waves to reach the ear or in vicinity of the ear of the wearer of the helmet.
    Type: Application
    Filed: August 30, 2022
    Publication date: December 29, 2022
    Inventor: Sebastian Schaefer
  • TREATMENT OF KIDNEY INJURY
    Publication number: 20220403017
    Abstract: Methods of treating and preventing kidney injury through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Application
    Filed: May 23, 2022
    Publication date: December 22, 2022
    Applicants: National University of Singapore, Singapore Health Services PTE LTD
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Anissa Anindya Widjaja
  • Separator plate arrangement for an electrochemical system
    Patent number: 11515603
    Abstract: A separator plate arrangement for an electrochemical system, comprising a first metal sheet and a second metal sheet. The first metal sheet has a first circumferential sealing structure for sealing off an electrochemically active region, a first cutout arranged outside of the first circumferential sealing structure, and a first embossed structure arranged outside of the first circumferential sealing structure. The second metal sheet has a second circumferential sealing structure for sealing off an electrochemically active region, a second cutout arranged outside of the second circumferential sealing structure, and a second embossed structure arranged outside of the second circumferential sealing structure.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: November 29, 2022
    Assignee: Reinz-Dichtungs-GmbH
    Inventors: Claudia Kunz, Sebastian Schaefer
  • DECOY CYTOKINE RECEPTOR
    Publication number: 20220298224
    Abstract: An IL-11 binding receptor capable of binding to IL-11 and inhibiting IL-11 mediated signalling is disclosed. Also disclosed are compositions comprising the IL-11 binding receptor and methods using the IL-11 binding receptor.
    Type: Application
    Filed: March 4, 2022
    Publication date: September 22, 2022
    Applicants: National University of Singapore, Singapore Health Services PTE LTD.
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • Treatment of kidney injury
    Patent number: 11339216
    Abstract: Methods of treating and preventing kidney injury through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Grant
    Filed: February 21, 2020
    Date of Patent: May 24, 2022
    Assignees: National University of Singapore, Singapore Health Services PTE LTD.
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Anissa Anindya Widjaja
  • Treatment of hepatotoxicity with IL-11 antibody
    Patent number: 11319368
    Abstract: Methods of treating and preventing hepatotoxicity through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods.
    Type: Grant
    Filed: January 21, 2020
    Date of Patent: May 3, 2022
    Assignees: Singapore Health Services PTE LTD., National University of Singapore
    Inventors: Stuart Alexander Cook, Sebastian Schaefer, Anissa Widjaja
  • BIPOLAR PLATE WITH STIFFENING STRUCTURES
    Publication number: 20220131162
    Abstract: A bipolar plate for an electrochemical system. The bipolar plate comprising a first individual plate and a second individual plate which are joined together. Each individual plate comprising: an electrochemically active region, an outer edge, and a perimeter sealing element. The outer edge region spans between the edge of the perimeter sealing element and the outer edge. Some emobidments of the outer edges protrude out of a plate plane defined by the bipolar plate. A plurality of stiffening structures stiffening the outer edge region of the bipolar plate.
    Type: Application
    Filed: October 26, 2021
    Publication date: April 28, 2022
    Inventors: Claudia KUNZ, Rainer GLUECK, Werner BUNTZ, Sebastian SCHAEFER
  • Decoy cytokine receptor
    Patent number: 11274143
    Abstract: An IL-11 binding receptor capable of binding to IL-11 and inhibiting IL-11 mediated signalling is disclosed. Also disclosed are compositions comprising the IL-11 binding receptor and methods using the IL-11 binding receptor.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: March 15, 2022
    Assignees: National University of Singapore, Singapore Health Services Pte Ltd
    Inventors: Stuart Alexander Cook, Sebastian Schaefer
  • IL-11R? antibodies
    Patent number: 11084878
    Abstract: Provided are antigen-binding molecules capable of binding to IL-11R?, and methods of medical treatment and prophylaxis using the same.
    Type: Grant
    Filed: June 13, 2019
    Date of Patent: August 10, 2021
    Assignees: National University of Singapore, Singapore Health Services PTE LTD., Boehringer Ingelheim International GmbH
    Inventors: Stuart Alexander Cook, Sebastian Schaefer