Patents by Inventor Sebastian Schieferdecker

Sebastian Schieferdecker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antimicrobial compounds, their use for the treatment of mammalian infections and a new metabolic mechanism
    Patent number: 11155542
    Abstract: The present invention relates to the general field of treatment of infectious diseases of mammals (humans and animals) caused by bacteria, in particular to the treatment of diseases like tuberculosis (TB), Buruli ulcer and leprosy caused by mycobacteria. The invention aims at the generation of a new series of benzothiazinone compounds having the potential to overcome the above mentioned problems. In a preferred embodiment the invention is concerned with compounds of the general formula (I) wherein R1 represents NO2, R2 represents CF3, at least one of the substituents R3 and R4 is OH, SR14, NHR15, CN, N3, a saturated or unsaturated, optionally halogenated, linear or branched aliphatic radical having 1-4 carbon atoms, linear or branched C1-C4 alkoxy, C1-C4 acyl, and the other of R3 and R4 may in addition be hydrogen, R6 represents a 2-methyl-1,4-dioxa-8-azaspiro[4.
    Type: Grant
    Filed: September 21, 2017
    Date of Patent: October 26, 2021
    Assignees: University of Notre Dame Du Lac
    Inventors: Florian Kloss, Sebastian Schieferdecker, Axel Brakhage, Julia Dreisbach, Marvin J. Miller, Ute Mollmann, Kamil Philip Wojtas
  • New antimicrobial compounds, their use for the treatment of mammalian infections and a new metabolic mechanism
    Publication number: 20200407351
    Abstract: The present invention relates to the general field of treatment of infectious diseases of mammals (humans and animals) caused by bacteria, in particular to the treatment of diseases like tuberculosis (TB), Buruli ulcer and leprosy caused by mycobacteria. The invention aims at the generation of a new series of benzothiazinone compounds having the potential to overcome the above mentioned problems. The invention is in a preferred embodiment concerned with compounds of the general formula (I), wherein the substituents R1 to R15 have the meanings as provided in claim 1 and depending claims.
    Type: Application
    Filed: September 21, 2017
    Publication date: December 31, 2020
    Inventors: Florian KLOSS, Sebastian SCHIEFERDECKER, Axel BRAKHAGE, Julia DREISBACH, Marvin J. MILLER, Ute MOLLMANN, Kamil Philip WOJTAS
  • NOVEL MACROLIDE ANTIBIOTICS
    Publication number: 20200231562
    Abstract: The present invention relates to a compound according to general formula (I), which exhibits bioactivity; methods for the production of the compound; to pharmaceutical compositions comprising one or more of the compound(s); and to the use of the compound(s) as a medicament.
    Type: Application
    Filed: July 7, 2015
    Publication date: July 23, 2020
    Inventors: Frank Surup, Heinrich Steinmetz, Kathrin Mohr, Konrad Viehrig, Rolf Müller, Markus Nett, Sebastian Schieferdecker, Hans-Martin Dahse, Michael Wolling, Andreas Kirschning