Abstract: A computer-implemented method for generating a synthetic training data set for training a machine learning computer vision model for performing at least one user defined computer vision task, in which spatially resolved sensor data are processed and evaluated with respect to at least one user defined object of interest, including receiving at least one model of a user defined object of interest; determining at least one render parameter and multiple render parameters; generating a set of training images by rendering the at least one model of the object of interest based on the at least one render parameter; generating annotation data for the set of training images with respect to the at least one object of interest; and providing a training data set including the set of training images and the annotation data for being output to the user and/or for training the computer vision model.

Abstract: A method for the use of a cytochrome P450 enzyme comprising any of SEQ ID NO: 1-118, or mutants thereof or a variant enzyme having at least 70% identity thereto and having CYP450 activity, for the hydroxylation and or dealkylation of an organic compound.

Abstract: A maintenance planning system for a production plant comprises: a production planning system for determining a production sequence for the production plant; an automation system for controlling production in the production plant; a state monitoring system for acquiring states of the production plant and its components; and a business planning system for the economic management of production and maintenance in the production plant. The maintenance planning system is designed for determining maintenance measures for the production plant. When determining the maintenance measures, the maintenance planning system takes into account the information of the production planning system, the automation system, the state monitoring system and the business planning system and performs optimization with regard to an economic utilization of the production plant. The disclosure further relates to a method for determining maintenance measures for a production plant and corresponding computer programs.

Abstract: In a system for optimizing production installations and/or processes of a metallurgical installation each production installation and/or process comprises a separate data management device. Entities of the metallurgical installation that are relevant for the respective part of the production installation and/or process are identifiable by local identifiers and the local identifiers can be used to retrieve data of separate data management devices. Within a central data management device each entity of the metallurgical installation has an associated global identifier. The applicable local identifiers of the separate data management devices are associated with the same entities of the metallurgical installation by the respective global identifier in the central data management device. Optimization involves at least some of the data from the separate data management devices being aggregated and evaluated by means of the global identifiers.

Abstract: The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 110, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound, wherein the amino acid residue at position 291 is not threonine.

Abstract: The present invention relates to a cytochrome P450 enzyme comprising the amino acid sequence set forth in SEQ ID NO: 3, or a variant thereof having an amino acid sequence having at least 95% identity thereto and having CYP450 activity. The cytochrome P450 enzyme provided herein was isolated from Streptomyces eurythermus NRRL 2539 and has a wide substrate range and high activity, and may be used to oxidate organic compounds.

Abstract: A molding tool made of carbon or graphite, namely a casting mold or a casting core for the processing of molten metal or to a molding tool for the processing of molten glass, such as for example a blow mold and a method for producing the molding tool.

Abstract: A computer-implemented method for generating a synthetic training data set for training a machine learning computer vision model for performing at least one user defined computer vision task, in which spatially resolved sensor data are processed and evaluated with respect to at least one user defined object of interest, including receiving at least one model of a user defined object of interest; determining at least one render parameter and multiple render parameters; generating a set of training images by rendering the at least one model of the object of interest based on the at least one render parameter; generating annotation data for the set of training images with respect to the at least one object of interest; and providing a training data set including the set of training images and the annotation data for being output to the user and/or for training the computer vision model.

Abstract: The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 3, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound.

Abstract: A system for confirming the identity of a vehicle. The device includes: a vehicle control unit in the vehicle to be identified; a vehicle identification device; an external service device designed to interact with the vehicle; a vehicle sensor in the vehicle; and an external sensor. The vehicle identification device establishes a data connection with the vehicle control unit and triggers a physical interaction between the vehicle control unit and the external service device. The vehicle sensor detects the physical interaction and transmits a corresponding vehicle detection value to the vehicle identification device. The external sensor detects the physical interaction and transmits a corresponding external detection value to the vehicle identification device; and the vehicle identification device compares the vehicle detection value and the external detection value with one another and confirms the identity of the vehicle if the two detection values coincide with one another within a predefined tolerance.

Abstract: A circuit for an I/O module, the circuit having a communication unit for receiving process data, which is connectable to a bus for communication purposes, a microcontroller which is connected to the communication unit, a load, a digital/analog converter, which includes a current output driver for outputting an output current to the load, and a first DC/DC converter. The microcontroller is connected to the digital/analog converter via a digital interface and is configured to set the output current of the digital/analog converter via the digital interface based on the received process data. The microcontroller is configured to output a control signal to a first DC/DC converter via the control interface for setting the first supply voltage based on the output current and the digital voltage value.

Abstract: A method for the use of a cytochrome P450 enzyme comprising any of SEQ ID NO: 1-118, or mutants thereof or a variant enzyme having at least 70% identity thereto and having CYP450 activity, for the hydroxylation and or dealkylation of an organic compound.

Abstract: A method for connecting components having a fibre-reinforced thermoplastic plastic includes provision of a first component with a first joining surface, provision of a second component with a second joining surface, flush placement of the first joining surface against the second joining surface in order to form a connection joint, placement of a friction stir welding tool against the connection joint, or a surface directly adjacent thereto, of at least one of the components, softening of the first component and the second component, in each case in a region adjacent to the connection joint, by rotation of the tool, such that the thermoplastic plastic of the two components locally fuses, and movement of the tool along the connection joint for the purposes of connecting the two components by formation of a fusion seam, wherein portions of reinforcement fibres are stirred in to increase the strength of the fusion seam.

Abstract: The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 110, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound, wherein the amino acid residue at position 291 is not threonine.

Abstract: A system for confirming the identity of a vehicle. The device includes: a vehicle control unit in the vehicle to be identified; a vehicle identification device; an external service device designed to interact with the vehicle; a vehicle sensor in the vehicle; and an external sensor. The vehicle identification device establishes a data connection with the vehicle control unit and triggers a physical interaction between the vehicle control unit and the external service device. The vehicle sensor detects the physical interaction and transmits a corresponding vehicle detection value to the vehicle identification device. The external sensor detects the physical interaction and transmits a corresponding external detection value to the vehicle identification device; and the vehicle identification device compares the vehicle detection value and the external detection value with one another and confirms the identity of the vehicle if the two detection values coincide with one another within a predefined tolerance.

Abstract: A method for connecting components having a fibre-reinforced thermoplastic plastic includes provision of a first component with a first joining surface, provision of a second component with a second joining surface, flush placement of the first joining surface against the second joining surface in order to form a connection joint, placement of a friction stir welding tool against the connection joint, or a surface directly adjacent thereto, of at least one of the components, softening of the first component and the second component, in each case in a region adjacent to the connection joint, by rotation of the tool, such that the thermoplastic plastic of the two components locally fuses, and movement of the tool along the connection joint for the purposes of connecting the two components by formation of a fusion seam, wherein portions of reinforcement fibres are stirred in to increase the strength of the fusion seam.

Abstract: A method for operating a motor vehicle, in particular a passenger vehicle, having at least one drive engine and an automatic transmission. A motor vehicle with conventional shift transmission is imitated by providing a clutch pedal for separating the drive connection, a shift lever for the manual shifting of the gear ratios, and an electronic control unit, by which the functions of clutching and shifting are converted into corresponding control signals for the automatic transmission.

Abstract: The use of a cytochrome P-450 enzyme comprising SEQ ID NO: 3, or a variant enzyme having at least 70% identity thereto and having CYP-450 activity, for the hydroxylation of an organic compound.

Abstract: A method is provided for operating a trace procedure, which traces execution of a computer program, where the program uses different callable modules. A program stack is used to store trace buffer information and an error state, and the modules include calls of the trace procedure. The method includes: (i) when entering execution of a module, storing the current write position of the trace buffer and a cleared error flag in the current frame of the stack; (ii) in case of an error condition during execution of the program, setting the error flag in the current frame; and (iii) when leaving execution of a module, determining if the error flag is set, and if not, then rewinding the trace buffer to the write position stored in the current frame, and deleting the current write position of the trace buffer and the error flag from the stack.

Abstract: A centrifugal pendulum device includes a pendulum mass carrier, which is rotatable about a rotation axis, and at least one pendulum mass, which is supported on the pendulum mass carrier for movement along a track between end stops which are spaced from one another in circumferential direction in relation to the rotation axis. A spring device urges the pendulum mass in one of the end stops, when the rotation speed of the pendulum mass carrier drops below a limit rotation speed.