Patents by Inventor Sebastian Suerbaum

Sebastian Suerbaum has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • H. pylori FlbA polypeptides, immunogenic and vaccinating compositions comprising H. pylori FlbA polypeptides, and compositions for detection of an infection comprising H. pylori FlbA polypeptides
    Publication number: 20050147988
    Abstract: The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori, to the proteins encoded by these sequences and to aflagellate bacterial strains. The invention also relates to the use of these means for detecting an infection due to H. pylori or for protecting against such an infection.
    Type: Application
    Filed: August 26, 2004
    Publication date: July 7, 2005
    Inventors: Sebastian Suerbaum, Agnes Labigne
  • H. PYLORI FLBA POLYPEPTIDES, IMMUNOGENIC AND VACCINATING COMPOSITIONS COMPRISING H. PYLORI FLBA POLYPEPTIDES, AND COMPOSITIONS FOR DETECTION OF AN INFECTION COMPRISING H. PYLORI FLBA POLYPEPTIDES
    Patent number: 6899881
    Abstract: The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori, to the proteins encoded by these sequences and to a aflagellate bacterial strains. The invention also relates to the use of these means for detecting an infection due to H.pylori or for protecting against such an infection.
    Type: Grant
    Filed: September 10, 2002
    Date of Patent: May 31, 2005
    Assignees: Institut Pasteur, Institute National de la Sante et de la Recherche Medicale
    Inventors: Sebastian Suerbaum, Agnés Labigne
  • Cloning and characterization of the FLBA gene of H. pylori, production of aflagellate strains
    Patent number: 6838273
    Abstract: The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori, to the proteins encoded by these sequences and to aflagellate bacterial strains. The invention also relates to the use of these means for detecting an infection due to H.pylori or for protecting against such an infection.
    Type: Grant
    Filed: January 29, 1998
    Date of Patent: January 4, 2005
    Assignee: Institut Pasteur and Institut National de la Sante et de la Recherche Medicale
    Inventors: Sebastian Suerbaum, Agnès Labigne
  • H. pylori flbA polypeptides, immunogenic and vaccinating compositions comprising H. pylori flbA polypeptides, and compositions for detection of an infection comprising H. pylori flbA polypeptides
    Publication number: 20030195349
    Abstract: The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori, to the proteins encoded by these sequences and to aflagellate bacterial strains. The invention also relates to the use of these means for detecting an infection due to H.pylori or for protecting against such an infection.
    Type: Application
    Filed: September 10, 2002
    Publication date: October 16, 2003
    Applicant: Institut Pasteur and Institut National De La Sante Et De La Recherche Medicale
    Inventors: Sebastian Suerbaum, Agnes Labigne
  • CLONING AND CHARACTERIZATION OF THE FLBA GENE OF H. PYLORI, PRODUCTION OF AFLAGELLATE STRAINS
    Publication number: 20030152579
    Abstract: The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori, to the proteins encoded by these sequences and to aflagellate bacterial strains. The invention also relates to the use of these means for detecting an infection due to H.pylori or for protecting against such an infection.
    Type: Application
    Filed: January 29, 1998
    Publication date: August 14, 2003
    Applicant: INSTITUT PASTEUR AND INSTITUT NATIONAL DE LA SANTE
    Inventors: SEBASTIAN SUERBAUM, AGNES LABIGNE
  • Cloning and characterization of FLBA gene of H. pylori production of aflagellate
    Patent number: 6476213
    Abstract: The present application relates to nucleotide sequences which regulate the biosynthesis of the flagella proteins Helicobacter pylori, to the proteins encoded by these sequences and to aflagellate bacterial strains. The invention also relates to the use of these means for detecting an infection due to H . pylori or for protecting against such an infection.
    Type: Grant
    Filed: June 28, 1996
    Date of Patent: November 5, 2002
    Assignees: Institut Pasteur, Institut National de la Sante et de la Recherche Medicale
    Inventors: Sebastian Suerbaum, Agnès Labigne
  • Immunogenic compositions against helicobacter infection, polypeptides for use in the compositions, and nucleic acid sequences encoding said polypeptides
    Patent number: 6258359
    Abstract: There is provided an immunogenic composition capable of inducing protective antibodies against Helicobacter infection characterized in that it comprises: i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori (SEQ ID NO: 22,26), or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter felis urease (SEQ ID NO: 20-21), and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis (SEQ ID NO: 20-21), or a fragment thereof, said fragment being recognized by antibodies reacting with Helicobacter pylori urease (SEQ ID NO: 22-26); ii) and/or, a heat shock protein (Hsp), or chaperonin, from Helicobacter, or a fragment of said protein. The preparation, by recombinant means, of such immunogenic compositions is also provided.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 10, 2001
    Assignee: Institut Pasteur
    Inventors: Agnes Labigne, Sebastian Suerbaum, Richard L. Ferrero, Jean-Michel Thiberge