Patents by Inventor Sebastian ULBERT

Sebastian ULBERT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for irradiating mammalian cells with electron beams and/or X-rays
    Patent number: 11802271
    Abstract: The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.
    Type: Grant
    Filed: March 14, 2018
    Date of Patent: October 31, 2023
    Assignee: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: Frank-Holm Rögner, Sebastian Ulbert, Jana Burkhardt, Javier Portillo, Jessy Schönfelder
  • Method for inactivating viruses using electron beams
    Patent number: 10881724
    Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: January 5, 2021
    Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
    Inventors: Sebastian Ulbert, Christiane Wetzel
  • METHOD FOR IRRADIATING MAMMALIAN CELLS WITH ELECTRON BEAMS AND/OR X-RAYS
    Publication number: 20200102539
    Abstract: The present invention relates to a method for irradiating a population of mammalian cells comprising at least one target mammalian cell with electron beams and/or X-rays, characterized in that: (i) a composition comprising a population of mammalian cells is irradiated in vitro with electron beams and/or X-rays, the population of mammalian cells containing at least one target mammalian cell and the dose rate being within the range from 5 Gy/sec to 107 Gy/sec, and (ii) optionally viable target mammalian cells are isolated or enriched from the population of mammalian cells, and to agents obtainable thereby and to uses thereof.
    Type: Application
    Filed: March 14, 2018
    Publication date: April 2, 2020
    Applicant: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
    Inventors: FRANK-HOLM RÖGNER, SEBASTIAN ULBERT, JANA BURKHARDT, JAVIER PORTILLO, JESSY SCHÖNFELDER
  • METHOD FOR INACTIVATING VIRUSES USING ELECTRON BEAMS
    Publication number: 20180353594
    Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.
    Type: Application
    Filed: August 21, 2018
    Publication date: December 13, 2018
    Inventors: Sebastian ULBERT, Christiane WETZEL
  • Method for inactivating viruses using electron beams
    Patent number: 10080795
    Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.
    Type: Grant
    Filed: July 25, 2014
    Date of Patent: September 25, 2018
    Assignee: Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V.
    Inventors: Sebastian Ulbert, Christiane Wetzel
  • Distinguishing flavivirus infection using a recombinant mutant envelope protein
    Patent number: 10060924
    Abstract: The present invention relates to mutant peptides of the E protein of the West Nile virus and other flaviviruses useful for discriminating flaviviral infections, as well as kits, methods and uses related thereto.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: August 28, 2018
    Assignees: Fraunhofer-Gesellschaft Zur Förderung Der Angewandten Forschung E.V., Washington University
    Inventors: Sebastian Ulbert, Stefan Chabierski, Michael Diamond, Daved Fremont
  • DISTINGUISHING FLAVIVIRUS INFECTION USING A RECOMBINANT MUTANT ENVELOPE PROTEIN
    Publication number: 20170089897
    Abstract: The present invention relates to mutant peptides of the E protein of the West Nile virus and other flaviviruses useful for discriminating flaviviral infections, as well as kits, methods and uses related thereto.
    Type: Application
    Filed: August 22, 2014
    Publication date: March 30, 2017
    Inventors: Sebastian Ulbert, Stefan Chabierski, Michael Diamond, Daved Fremont
  • METHOD FOR INACTIVATING VIRUSES USING ELECTRON BEAMS
    Publication number: 20160158339
    Abstract: The invention relates to a method for inactivating viruses, characterized in that an immunogenic composition or vaccine comprising at least one virus is irradiated with electron beams, said immunogenic composition or vaccine comprising at least one virus (i) being liquid, in particular being a suspension and (ii) comprising at least one viral immunogen, wherein the antigen structure is preferably substantially retained.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 9, 2016
    Inventors: Sebastian ULBERT, Christiane WETZEL