Abstract: The present invention pertains to antigen recognizing constructs against COL6A3 antigens. The invention in particular provides novel T cell receptor (TCR) based molecules which are selective and specific for the tumor expressed antigen COL6A3. The TCR of the invention, and COL6A3 antigen binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of COL6A3 expressing cancerous diseases. Further provided are nucleic acids encoding the antigen recognizing constructs of the invention, vectors comprising these nucleic acids, recombinant cells expressing the antigen recognizing constructs and pharmaceutical compositions comprising the compounds of the invention.

Abstract: A method of controlling a drive, in particular an electric drive, of an industrial machine, in which method a drive control controls a drive motor and the drive motor drives a mechanical system having one or more coupled components. The drive control carries out a simulation of the mechanical system of the machine with a simulation model and performs a feedforward control of the drive motor based on the simulation.

Abstract: Automation controller and method for operating the automation controller, wherein the automation controller includes Ethernet channels to which network interfaces can be assigned via a first register with a first register value and a second register with a second register value, where the assignments are made and these are examined for variances via test values.

Abstract: A water gun comprising a pressure tank, a nozzle, a tube and valve with a valve conduit has an increased shooting range if the pressure tank has an outlet being connected to an inlet of the tube, the tube has an outlet being connected to an inlet port of the valve conduit and an outlet port of the valve conduit is in fluid communication with the nozzle.

Abstract: A compressed air energy storage system is described, including a compressor fluidly coupled to a compressed air reservoir and an expansion train including at least a first turbine. The system further includes an electric machine aggregate configured: for converting electric power into mechanical power and driving the compressor therewith during the energy storing mode; and for converting mechanical power produced by the expansion train into electric power during the power production mode. A combustor is configured for receiving fuel and compressed air and producing combustion gas, and for supplying the combustion gas to the first turbine.

Abstract: According to some embodiments, system and methods are provided, comprising providing a dual-mode model for a reciprocating compressor, wherein the model includes a measurement mode and a tuning mode; receiving one or more inputs to the model from an operating reciprocating compressor; and in response to receipt of the one or more inputs, executing the model in at least one of the measurement mode and the tuning mode, wherein: in a measurement mode, execution of the model further comprises calculating an actual flow rate of gas in the compressor based on the one or more inputs; and in a tuning mode, execution of the model further comprises calculating one of an unloader setting and a speed set point of a physical element of the compressor for a given flow rate of gas. Numerous other aspects are provided.

Abstract: The invention relates to a water gun, in particular to a toy water gun comprising a supply line, which is adapted to supply a pressurized liquid from a source, a nozzle arrangement for ejecting the liquid to the environment as well as a valve for controlling a flow of the liquid in a direction from the supply line to the nozzle arrangement. The water gun additionally includes a flow-smoothing device, with the valve arranged behind the flow-smoothing device with respect to the flow direction.

Abstract: The invention relates to a method of controlling a drive, in particular an electric drive, of an industrial machine, in which method a drive control controls a drive motor and the drive motor drives a mechanical system having one or more coupled components. The method is characterized in that the drive control carries out a simulation of the mechanical system of the machine by means of a simulation model and performs a feedforward control of the drive motor based on the simulation.

Abstract: Systems and methods are provided for controlling exhaust gas recirculation (EGR). In one example, an engine system includes a first EGR valve coupling an exhaust manifold to an engine exhaust system, a second EGR valve coupling the exhaust manifold to an engine intake system, and a control unit. The control unit selectively adjusts a position of the first EGR valve based on a target amount, and adjusts a position of the second EGR valve based on the target amount and a position of the first EGR valve. Responsive to a first degradation condition of the first EGR valve, the control unit adjusts the position of the second EGR valve based on the target amount and based on a pressure of the first exhaust manifold, and responsive to a second degradation condition of the first EGR valve, adjusts the position of the second EGR valve based on the target amount.

Abstract: Customizing messages using character patches, by attaching a set of character patches to a substrate, using hook and loop fasteners. An assortment of character patches is selected and provided by a supplier. The user selects which ones, but not all, of the assortment to use, as a set, and arranges the set in a desired order to create a user-determined message. The selected character patches are mounted to one or more receptive patches on the substrate, in the arranged order, displaying the user-determined message. A sheet of the assortment of character patches, die-cut in a character patch layer, can be supplied mounted on a backing layer. As the user selects and removes character patches, the remaining character patches remain all together, mounted on the backing layer. The characters include at least one of numbers, letters, or other readily-recognized non-artistic characters, and can include characters which contain only artistic expressions.

Abstract: The invention relates to a water gun, in particular to a toy water gun comprising a supply line, which is adapted to supply a pressurized liquid from a source, a nozzle arrangement for ejecting the liquid to the environment as well as a valve for controlling a flow of the liquid in a direction from the supply line to the nozzle arrangement. The water gun additionally includes a flow-smoothing device, with the valve arranged behind the flow-smoothing device with respect to the flow direction.

Abstract: The present application provides a heat exchanger for exchanging heat between two fluid flows in cross-flow arrangement. The heat exchanger includes at least one heat exchanging module including a first heat exchanging component and a second heat exchanging component. The first heat exchanging component including a fluid inlet header, a fluid outlet header, and at least one heat exchanging passageway defining a first tube-side fluid flow path of a first portion of a fluid in a first direction. The second heat exchanging component including a fluid inlet header, a fluid outlet header, and at least one heat exchanging passageway defining a second tube-side fluid flow path in a second direction for an additional portion of the fluid, wherein the first direction is opposed to the second direction. The opposing first tube-side fluid flow path and the second tube-side fluid flow path equalizing the temperature distribution over the cross-section of a cross-flow fluid exiting the module.

Abstract: Systems and methods are provided for controlling exhaust gas recirculation (EGR). In one example, an engine system includes a first EGR valve coupling an exhaust manifold to an engine exhaust system, a second EGR valve coupling the exhaust manifold to an engine intake system, and a control unit. The control unit selectively adjusts a position of the first EGR valve based on a target amount, and adjusts a position of the second EGR valve based on the target amount and a position of the first EGR valve. Responsive to a first degradation condition of the first EGR valve, the control unit adjusts the position of the second EGR valve based on the target amount and based on a pressure of the first exhaust manifold, and responsive to a second degradation condition of the first EGR valve, adjusts the position of the second EGR valve based on the target amount.

Abstract: Systems and methods are provided for controlling exhaust gas recirculation (EGR). In one example, an engine system includes a first EGR valve coupling an exhaust manifold to an engine exhaust system, a second EGR valve coupling the exhaust manifold to an engine intake system, and a control unit. The control unit selectively adjusts a position of the first EGR valve based on a target amount, and adjusts a position of the second EGR valve based on the target amount and a position of the first EGR valve. Responsive to a first degradation condition of the first EGR valve, the control unit adjusts the position of the second EGR valve based on the target amount and based on a pressure of the first exhaust manifold, and responsive to a second degradation condition of the first EGR valve, adjusts the position of the second EGR valve based on the target amount.

Abstract: A nozzle assembly of a turbocharger includes a nozzle and a ring-shaped body. The nozzle has flow passages extending through the nozzle and configured to direct air received from a volute housing of the turbocharger through the nozzle to turbine blades of the turbocharger. The ring-shaped body is coupled with the nozzle and is configured to rotate around the nozzle. The ring-shaped body includes blocking segments that block the flow of the air and openings between the blocking segments that permit the air to flow through the ring-shaped body. The ring-shaped body is configured to rotate relative to the nozzle to change how many of the flow passages in the nozzle are blocked by the blocking segments of the ring-shaped body.

Abstract: A compressed air energy storage system is described, including a compressor fluidly coupled to a compressed air reservoir and an expansion train including at least a first turbine. The system further includes an electric machine aggregate configured: for converting electric power into mechanical power and driving the compressor therewith during the energy storing mode; and for converting mechanical power produced by the expansion train into electric power during the power production mode. A combustor is configured for receiving fuel and compressed air and producing combustion gas, and for supplying the combustion gas to the first turbine.

Abstract: According to some embodiments, system and methods are provided, comprising providing a dual-mode model for a reciprocating compressor, wherein the model includes a measurement mode and a tuning mode; receiving one or more inputs to the model from an operating reciprocating compressor; and in response to receipt of the one or more inputs, executing the model in at least one of the measurement mode and the tuning mode, wherein: in a measurement mode, execution of the model further comprises calculating an actual flow rate of gas in the compressor based on the one or more inputs; and in a tuning mode, execution of the model further comprises calculating one of an unloader setting and a speed set point of a physical element of the compressor for a given flow rate of gas. Numerous other aspects are provided.

Abstract: The present application provides a heat exchanger for exchanging heat between two fluid flows in cross-flow arrangement. The heat exchanger includes at least one heat exchanging module including a first heat exchanging component and a second heat exchanging component. The first heat exchanging component including a fluid inlet header, a fluid outlet header, and at least one heat exchanging passageway defining a first tube-side fluid flow path of a first portion of a fluid in a first direction. The second heat exchanging component including a fluid inlet header, a fluid outlet header, and at least one heat exchanging passageway defining a second tube-side fluid flow path in a second direction for an additional portion of the fluid, wherein the first direction is opposed to the second direction. The opposing first tube-side fluid flow path and the second tube-side fluid flow path equalizing the temperature distribution over the cross-section of a cross-flow fluid exiting the module.