Patents by Inventor Sebastian Weingartner

Sebastian Weingartner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10962617
    Abstract: Methods for fast magnetic resonance imaging (“MRI”) using a combination of outer volume suppression (“OVS”) and accelerated imaging, which may include simultaneous multislice (“SMS”) imaging, data acquisitions amenable to compressed sensing reconstructions, or combinations thereof. The methods described here do not introduce fold-over artifacts that are otherwise common to reduced field-of-view (“FOV”) techniques.
    Type: Grant
    Filed: April 6, 2018
    Date of Patent: March 30, 2021
    Assignee: Regents of the University of Minnesota
    Inventors: Sebastian Weingartner, Steen Moeller, Mehmet Akcakaya
  • Publication number: 20200289011
    Abstract: Systems and methods for performing online spike recovery from multi-channel electrophysiological recordings in accordance with various embodiments of the invention are described. One embodiment of a method of performing online spike recovery from multi-channel electrophysiological recordings includes: determining a set of waveform templates; continuously obtaining multi-channel electrophysiological recordings using a multi-channel electrode; and automatically performing online spike recovery from the multi-channel electrophysiological recordings using a processing system that performs a method for sparse signal recovery that continuously adjusts a processing buffer size based upon newly obtained multi-channel electrophysiological recordings.
    Type: Application
    Filed: March 9, 2020
    Publication date: September 17, 2020
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Sebastian Weingärtner, Tirin Moore
  • Patent number: 10775464
    Abstract: Systems and methods for producing quantitative maps of a longitudinal relaxation parameter, such as a longitudinal relaxation time (“T1”), using magnetic resonance imaging (“MRI”) are described. More particularly, a pulse sequence and imaging method for cardiac phase-resolved myocardial T1 mapping are provided.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: September 15, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Patent number: 10739420
    Abstract: Systems and methods for mapping the transmit sensitivity of one or more radio frequency (“RF”) coils for use in magnetic resonance imaging (“MRI”) are described. The transmit RF field (“B1+”) for an RF coil, or an array of RF coils, is mapped using a robust, motion-insensitive technique that implements Bloch-Siegert shifts performed with interleaved positive and negative off-resonance shifts. The motion insensitivity of this technique makes it particularly useful for applications where there is significant motion, such as cardiac imaging, in which previous B1+ mapping techniques are not as accurate or effective.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: August 11, 2020
    Assignee: Regents of the University of Minnesota
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Publication number: 20200041591
    Abstract: Systems and methods for late gadolinium enhancement (“LGE”) tissue viability imaging in a dynamic (e.g., temporal-ly-resolved) manner using magnetic resonance imaging (“MRI”) are provided. Dynamic LGE images can be generated throughout the entire cardiac cycle at high temporal resolution in a single breath-hold. Dynamic, semi-quantitative longitudinal relaxation maps are acquired and retrospective synthetization of dynamic LGE images is implemented using those semi-quantitative longitudinal relaxation maps.
    Type: Application
    Filed: January 31, 2018
    Publication date: February 6, 2020
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Patent number: 10531812
    Abstract: A system and method for controlling a magnetic resonance imaging (MRI) system to acquire images of a subject having inconsistencies in a cardiac cycle of the subject. The process includes receiving an identification of a predetermined point in a cardiac cycle of the subject and, thereupon, performing a saturation module configured to dephase magnetization within a region of interest (ROI) from before the predetermined point. The process also includes performing an inversion module configured to invert spins within the ROI and acquiring medical imaging data from the subject. A delay is inserted between the performance of the saturation module and the performance of the inversion module, wherein a duration of the delay is configured, with the saturation module, to control evidence in the medical imaging data of inconsistencies in the cardiac cycle of the subject by controlling a magnetization history of tissue in the ROI.
    Type: Grant
    Filed: January 16, 2013
    Date of Patent: January 14, 2020
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Sebastian Weingärtner, Mehmet Akçakaya, Warren J. Manning, Reza Nezafat
  • Patent number: 10520570
    Abstract: An MRI method includes: performing a first data acquisition block of a pulse sequence to acquire a first MR data from a plurality of slices of a subject during a period of fully recovered longitudinal magnetization within the plurality of slices disposed at different locations in the subject; performing a second data acquisition block of the pulse sequence including a magnetization preparation module followed by a recovery period and an imaging sequence executed during the recovery period, to acquire a second MR data from the plurality of slices during the recovery period; and generating a T1 map of the subject based on the first MR data and the second MR data, of the plurality of slices.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: December 31, 2019
    Assignee: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventors: Sebastian Weingartner, Reza Nezafat
  • Patent number: 10451700
    Abstract: A system and method for obtaining magnetic resonance images are provided. The system is programmed to control the RF system to apply a saturation pulse at a reference frequency that saturates a selected labile spin species of the subject. The system is programmed to control the RF system to apply an inversion pulse after a variable delay. The system is programmed to control the RF system and the plurality of gradient coils to apply a motion sensitized driven equilibrium (MSDE) preparation pulse. The system is programmed to control the plurality of gradient coils to read imaging data during an acquisition time period. The system is programmed to reconstruct a T1 mapping image of the subject with black-blood contrast.
    Type: Grant
    Filed: September 5, 2017
    Date of Patent: October 22, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Publication number: 20180292487
    Abstract: Methods for fast magnetic resonance imaging (“MRI”) using a combination of outer volume suppression (“OVS”) and accelerated imaging, which may include simultaneous multislice (“SMS”) imaging, data acquisitions amenable to compressed sensing reconstructions, or combinations thereof. The methods described here do not introduce fold-over artifacts that are otherwise common to reduced field-of-view (“FOV”) techniques.
    Type: Application
    Filed: April 6, 2018
    Publication date: October 11, 2018
    Inventors: Sebastian Weingartner, Steen Moeller, Mehmet Akcakaya
  • Publication number: 20180217217
    Abstract: Systems and methods for producing quantitative maps of a longitudinal relaxation parameter, such as a longitudinal relaxation time (“T1”), using magnetic resonance imaging (“MRI”) are described. More particularly, a pulse sequence and imaging method for cardiac phase-resolved myocardial T1 mapping are provided.
    Type: Application
    Filed: January 31, 2018
    Publication date: August 2, 2018
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Publication number: 20180067184
    Abstract: A system and method for obtaining magnetic resonance images are provided. The system is programmed to control the RF system to apply a saturation pulse at a reference frequency that saturates a selected labile spin species of the subject. The system is programmed to control the RF system to apply an inversion pulse after a variable delay. The system is programmed to control the RF system and the plurality of gradient coils to apply a motion sensitized driven equilibrium (MSDE) preparation pulse. The system is programmed to control the plurality of gradient coils to read imaging data during an acquisition time period. The system is programmed to reconstruct a T1 mapping image of the subject with black-blood contrast.
    Type: Application
    Filed: September 5, 2017
    Publication date: March 8, 2018
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Publication number: 20180067176
    Abstract: Systems and methods for mapping the transmit sensitivity of one or more radio frequency (“RF”) coils for use in magnetic resonance imaging (“MRI”) are described. The transmit RF field (“B1+”) for an RF coil, or an array of RF coils, is mapped using a robust, motion-insensitive technique that implements Bloch-Siegert shifts performed with interleaved positive and negative off-resonance shifts. The motion insensitivity of this technique makes it particularly useful for applications where there is significant motion, such as cardiac imaging, in which previous B1+ mapping techniques are not as accurate or effective.
    Type: Application
    Filed: September 6, 2017
    Publication date: March 8, 2018
    Inventors: Sebastian Weingartner, Mehmet Akcakaya
  • Patent number: 9835705
    Abstract: A magnetic resonance imaging (MRI) system and methods are provided for producing images of a subject. In some aspects, a method includes identifying a point in the cardiac cycle, performing an inversion recovery (IR) pulse at a selected time point from the pre-determined point, and sampling a k-space segment at an inversion time from the IR pulse that is substantially coincident with the pre-determined point. The method also includes repeating the IR pulse and k-space sampling for multiple inversion times, and multiple segments of k-space, in an interleaved manner, to generate datasets having T1-weighted contrasts determined by their respective inversion times. The method further includes reconstructing three-dimensional (3D) spatially-aligned images using the datasets, and generating a T1 recovery map by combining the 3D images. In some aspects, a prospective/retrospective scheme may be used to obtain data fully sampled in the center of k-space and randomly undersampled in the outer regions.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: December 5, 2017
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Sebastian Weingartner, Mehmet Akcakaya, Reza Nezafat
  • Publication number: 20150323630
    Abstract: An MRI method includes: performing a first data acquisition block of a pulse sequence to acquire a first MR data from a plurality of slices of a subject during a period of fully recovered longitudinal magnetization within the plurality of slices disposed at different locations in the subject; performing a second data acquisition block of the pulse sequence including a magnetization preparation module followed by a recovery period and an imaging sequence executed during the recovery period, to acquire a second MR data from the plurality of slices during the recovery period; and generating a T1 map of the subject based on the first MR data and the second MR data, of the plurality of slices.
    Type: Application
    Filed: May 7, 2015
    Publication date: November 12, 2015
    Applicant: BETH ISRAEL DEACONESS MEDICAL CENTER, INC.
    Inventors: Sebastian WEINGARTNER, Reza NEZAFAT
  • Publication number: 20150123659
    Abstract: A magnetic resonance imaging (MRI) system and methods are provided for producing images of a subject. In some aspects, a method includes identifying a point in the cardiac cycle, performing an inversion recovery (IR) pulse at a selected time point from the pre-determined point, and sampling a k-space segment at an inversion time from the IR pulse that is substantially coincident with the pre-determined point. The method also includes repeating the IR pulse and k-space sampling for multiple inversion times, and multiple segments of k-space, in an interleaved manner, to generate datasets having T1-weighted contrasts determined by their respective inversion times. The method further includes reconstructing three-dimensional (3D) spatially-aligned images using the datasets, and generating a T1 recovery map by combining the 3D images. In some aspects, a prospective/retrospective scheme may be used to obtain data fully sampled in the center of k-space and randomly undersampled in the outer regions.
    Type: Application
    Filed: November 7, 2014
    Publication date: May 7, 2015
    Inventors: Sebastian Weingartner, Mehmet Akcakaya, Reza Nezafat
  • Publication number: 20140200436
    Abstract: A system and method for controlling a magnetic resonance imaging (MRI) system to acquire images of a subject having inconsistencies in a cardiac cycle of the subject. The process includes receiving an identification of a predetermined point in a cardiac cycle of the subject and, thereupon, performing a saturation module configured to dephase magnetization within a region of interest (ROI) from before the predetermined point. The process also includes performing an inversion module configured to invert spins within the ROI and acquiring medical imaging data from the subject. A delay is inserted between the performance of the saturation module and the performance of the inversion module, wherein a duration of the delay is configured, with the saturation module, to control evidence in the medical imaging data of inconsistencies in the cardiac cycle of the subject by controlling a magnetization history of tissue in the ROI.
    Type: Application
    Filed: January 16, 2013
    Publication date: July 17, 2014
    Inventors: Sebastian Weingärtner, Mehmet Akçakaya, Warren J. Manning, Reza Nezafat