Patents by Inventor Sebastien MORISSEAU

Sebastien MORISSEAU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Specific interleukin-15 (IL-15) antagonist polypeptide and uses thereof for the treatment of inflammatory and auto-immune diseases
    Patent number: 10858452
    Abstract: The present invention relates to specific interleukin-15 (IL-15) antagonist polypeptides and uses thereof for the treatment of inflammatory and auto-immune diseases. In particular, the present invention relates to a specific interleukin-15 (IL-15) antagonist polypeptide comprising i) a IL15-Ralpha sushi-containing polypeptide comprising an amino acid sequence having at least 80% of identity with the amino acid sequence of SEQ ID NO:1 ii) a linker and iii) an IL-polypeptide comprising the amino acid sequence having at least at least 80% of identity with the amino acid sequence of SEQ ID NO:4 provided that the glutamine (Q) residue at position 108 is mutated.
    Type: Grant
    Filed: September 15, 2016
    Date of Patent: December 8, 2020
    Assignees: Insitut National de la Sante et de la Recherche Medicale (INSERM), Universite de Nantes, Universite d'Angers, Centre National de la Recherche Scientifique, Centre Hospitalier Universitaire de Nantes
    Inventors: Erwan Mortier, Dihia Meghnem, Sebastien Morisseau, Yannick Jacques
  • SPECIFIC INTERLEUKIN-15 (IL-15) ANTAGONIST POLYPEPTIDE AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY AND AUTO-IMMUNE DISEASES
    Publication number: 20180258174
    Abstract: The present invention relates to specific interleukin-15 (IL-15) antagonist polypeptides and uses thereof for the treatment of inflammatory and auto-immune diseases. In particular, the present invention relates to a specific interleukin-15 (IL-15) antagonist polypeptide comprising i) a IL15-Ralpha sushi-containing polypeptide comprising an amino acid sequence having at least 80% of identity with the amino acid sequence of SEQ ID NO:1 ii) a linker and iii) an IL-polypeptide comprising the amino acid sequence having at least at least 80% of identity with the amino acid sequence of SEQ ID NO:4 provided that the glutamine (Q) residue at position 108 is mutated.
    Type: Application
    Filed: September 15, 2016
    Publication date: September 13, 2018
    Inventors: Erwan MORTIER, Dihia MEGHNEM, Sebastien MORISSEAU, Yannick JACQUES