Patents by Inventor Sebastien Naud

Sebastien Naud has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190281828
    Abstract: The present invention relates to novel triazole derivatives of formula (I) wherein A, R2, R4, m, and Y are defined as in the claims, to compositions comprising these compounds, to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials, and to intermediates useful for preparing these compounds.
    Type: Application
    Filed: September 18, 2017
    Publication date: September 19, 2019
    Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Pierre-Yves COQUERON, Ricarda MILLER, David BERNIER, Sebastien NAUD, Pierre GENIX, Philippe KENNEL, Stephane BRUNET, Sven WITTROCK, Sebastian HOFFMANN
  • Patent number: 10399974
    Abstract: The present invention relates to compounds of formula I: wherein R1, R2, R3 and R4 are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: January 3, 2018
    Date of Patent: September 3, 2019
    Assignee: Cancer Research Technology Limited
    Inventors: Hannah Woodward, Paolo Innocenti, Sebastien Naud, Julian Blagg, Swen Hoelder
  • Publication number: 20190218188
    Abstract: The present invention relates to novel 5-substituted imidazolylmethyl derivatives, to processes for preparing these compounds, to compositions and mixtures comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: September 22, 2017
    Publication date: July 18, 2019
    Inventors: Pierre-Yves COQUERON, David BERNIER, Pierre GENIX, Ricarda MILLER, Sebastien NAUD, Sven WITTROCK
  • Publication number: 20190218187
    Abstract: The present invention relates to novel 5-substituted imidazolylmethyl derivatives, to processes for preparing these compounds, to compositions and mixtures comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: September 22, 2017
    Publication date: July 18, 2019
    Inventors: Pierre-Yves COQUERON, David BERNIER, Ricarda MILLER, Pierre GENIX, Sebastien NAUD, Sven WITTROCK, Stephane BRUNET, Philippe KENNEL, Ruth MEISSNER, Ulrike WACHENDORFF-NEUMANN
  • Publication number: 20190211002
    Abstract: The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: September 18, 2017
    Publication date: July 11, 2019
    Inventors: Pierre-Yves COQUERON, Ricarda MILLER, David BERNIER, Sebastien NAUD, Pierre GENIX, Sven WITTROCK, Philippe KENNEL, Stephane BRUNET, Sebastian HOFFMANN, Ruth MEISSNER
  • Publication number: 20190082691
    Abstract: The present invention relates to novel 5-substituted imidazolylmethyl derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: November 14, 2018
    Publication date: March 21, 2019
    Inventors: Sebastian HOFFMANN, Hendrik HELMKE, Peter DAHMEN, Ulrike WACHENDORFF-NEUMANN, David BERNIER, Ricarda MILLER, Pierre-Yves COQUERON, Pierre GENIX, Sven WITTROCK, Jean-Pierre VORS, Philippe KENNEL, Stephane BRUNET, Sebastien NAUD, Ruth MEISSNER
  • Patent number: 10231453
    Abstract: The present invention relates to novel 5-substituted imidazolylmethyl derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Grant
    Filed: March 29, 2016
    Date of Patent: March 19, 2019
    Assignee: BAYER CROPSCIENCE AKTIENGESELLSCHAFT
    Inventors: Sebastian Hoffmann, Hendrik Helmke, Peter Dahmen, Ulrike Wachendorff-Neumann, David Bernier, Ricarda Miller, Pierre-Yves Coqueron, Pierre Genix, Sven Wittrock, Jean-Pierre Vors, Philippe Kennel, Stephane Brunet, Sebastien Naud, Ruth Meissner
  • Publication number: 20180339976
    Abstract: The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: March 29, 2016
    Publication date: November 29, 2018
    Inventors: ALEXANDER SUDAU, SEBASTIAN HOFFMANN, PETER DAHMEN, ULRIKE WACHENDORFF-NEUMANN, DAVID BERNIER, RICARDA MILLER, PIERRE-YVES COQUERON, PIERRE GENIX, SVEN WITTROCK, JEAN-PIERRE VORS, PHILIPPE KENNEL, STEPHANE BRUNET, SEBASTIEN NAUD, RUTH MEISSNER
  • Publication number: 20180235223
    Abstract: The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: August 11, 2016
    Publication date: August 23, 2018
    Inventors: Sebastian HOFFMANN, Alexander SUDAU, Peter DAHMEN, Ulrike WACHENDORFF-NEUMANN, Ruth MEISSNER, Julie GEIST, David BERNIER, Jean-Pierre VORS, Pierre-Yves COQUERON, Sven WITTROCK, Ricarda MILLER, Sebastien NAUD, Stephane BRUNET, Pierre GENIX, Philippe KENNEL
  • Publication number: 20180194761
    Abstract: The present invention relates to compounds of formula I: wherein R1, R2, R3 and R4 are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 3, 2018
    Publication date: July 12, 2018
    Inventors: Hannah Woodward, Paolo Innocenti, Sebastien Naud, Julian Blagg, Swen Hoelder
  • Publication number: 20180141944
    Abstract: The present invention relates to compounds of formula I wherein R1, R4, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: January 8, 2018
    Publication date: May 24, 2018
    Inventors: Swen Hoelder, Julian Blagg, Savade Solanki, Hannah Woodward, Sebastien Naud, Vassilios Bavetsias, Peter Sheldrake, Paolo Innocenti, Kwai-Ming J. Cheung, Butrus Atrash
  • Publication number: 20180116220
    Abstract: The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: March 29, 2016
    Publication date: May 3, 2018
    Inventors: GORKA PERIS, JUERGEN BENTING, II, PETER DAHMEN, ULRIKE WACHENDORFF-NEUMANN, PIERRE-YVES COQUERON, SVEN WITTROCK, RICARDA MILLER, DAVID BERNIER, JEAN-PIERE VORS, PHILIPPE KENNEL, PIERRE GENIX, SEBASTIEN NAUD, RUTH MEISSNER, STEPHANE BRUNET
  • Publication number: 20180084780
    Abstract: The present invention relates to novel 5-substituted imidazolylmethyl derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: March 29, 2016
    Publication date: March 29, 2018
    Inventors: SEBASTIAN HOFFMANN, HENDRIK HELMKE, PETER DAHMEN, ULRIKE WACHENDORFF-NEUMANN, DAVID BERNIER, RICARDA MILLER, PIERRE-YVES COQUERON, PIERRE GENIX, SVEN WITTROCK, JEAN-PIERRE VORS, PHILIPPE KENNEL, STEPHANE BRUNET, SEBASTIEN NAUD, RUTH MEISSNER
  • Publication number: 20180057467
    Abstract: The present invention relates to novel triazole derivatives, to processes for preparing these compounds, to compositions comprising these compounds, and to the use thereof as biologically active compounds, especially for control of harmful microorganisms in crop protection and in the protection of materials and as plant growth regulators.
    Type: Application
    Filed: March 29, 2016
    Publication date: March 1, 2018
    Inventors: GORKA PERIS, JUERGEN BENTING, II, PETER DAHMEN, ULRIKE WACHENDORFF-NEUMANN, PIERRE-YVES COQUERON, PIERRE GENIX, STEPHANE BRUNET, RICARDA MILLER, DAVID BERNIER, JEAN-PIERE VORS, SVEN WITTROCK, PHILIPPE KENNEL, SEBASTIEN NAUD, RUTH MEISSNER
  • Patent number: 9902721
    Abstract: The present invention relates to compounds of formula I: wherein R1, R2, R3 and R4 are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: February 27, 2018
    Assignee: Cancer Research Technology Limited
    Inventors: Hannah Woodward, Paolo Innocenti, Sebastien Naud, Julian Blagg, Swen Hoelder
  • Patent number: 9890157
    Abstract: The present invention relates to compounds of formula I wherein R1, R4, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: February 13, 2018
    Assignee: Cancer Research Technology Limited
    Inventors: Swen Hoelder, Julian Blagg, Savade Solanki, Hannah Woodward, Sebastien Naud, Vassilios Bavetsias, Peter Sheldrake, Paolo Innocenti, Kwai-Ming J. Cheung, Butrus Atrash
  • Patent number: 9834552
    Abstract: The present invention relates to compounds of formula I wherein R1, R4, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: April 6, 2016
    Date of Patent: December 5, 2017
    Assignee: Cancer Research Technology Limited
    Inventors: Swen Hoelder, Julian Blagg, Savade Solanki, Hannah Woodward, Sebastien Naud, Vassilios Bavetsias, Peter Sheldrake, Paolo Innocenti, Kwai-Ming J. Cheung, Butrus Atrash
  • Publication number: 20160362409
    Abstract: The present invention relates to compounds of formula I: wherein R1, R2, R3 and R4 are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: February 27, 2015
    Publication date: December 15, 2016
    Inventors: Hannah WOODWARD, Paolo INNOCENTI, Sebastien NAUD, Julian BLAGG, Swen HOELDER
  • Patent number: 9409907
    Abstract: The present invention relates to compounds of formula I wherein R1, R4, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Grant
    Filed: September 9, 2013
    Date of Patent: August 9, 2016
    Assignee: Cancer Research Technology Limited
    Inventors: Swen Hoelder, Julian Blagg, Savade Solanki, Hannah Woodward, Sebastien Naud, Vassilios Bavetsias, Peter Sheldrake, Paolo Innocenti, Kwai-Ming J. Cheung, Butrus Atrash
  • Publication number: 20160220570
    Abstract: The present invention relates to compounds of formula I wherein R1, R4, Ar, W, X and Z are all as defined herein. The compounds of the present invention are known to inhibit the spindle checkpoint function of Monospindle 1 (Mps1—also known as TTK) kinases either directly or indirectly via interaction with the Mps1 kinase itself. In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.
    Type: Application
    Filed: April 6, 2016
    Publication date: August 4, 2016
    Inventors: Swen Hoelder, Julian Blagg, Savade Solanki, Hannah Woodward, Sebastien Naud, Vassilios Bavetsias, Peter Sheldrake, Paolo Innocenti, Kwai-Ming J. Cheung, Butrus Atrash