Abstract: The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X, D, R1 to R4, and R6 to R10 are as described herein. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A and R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention provides novel imidazopyrazine derivatives having the general formula (I), or pharmaceutically acceptable salts thereof, wherein X and R3 to R9 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention provides novel imidazopyrazine derivatives having the general formula (I), wherein Rx and R3 to R5 are as described herein: or pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X, D, R1 to R4, and R6 to R10 are as described herein. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: Provided are novel imidazopyrazine derivatives having the general formula (I), wherein A and R1 to R11 are as described herein and pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and related diseases.

Abstract: Provided are novel imidazopyrazine derivatives having the general formula (I), wherein R1 to R11 are as described herein and pharmaceutically acceptable salts thereof. Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and related diseases.

Abstract: The disclosure provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X1, RA and R3 to R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention relates to a method for managing the reputation level of a first communication device (100), said reputation level (103) being stored into a first secure enclave (102) embedded in said first communication device (100). The method comprises the steps of: receiving from the first communication device (100) by a second communication device (110) an information message; verifying that the information message is consistent with data obtained from a sensor embedded in the second communication device (110); generating a feedback message by the second communication device (110) to be transmitted to the first communication device (100) indicating if the information message is consistent for the secure enclave (102) of the first communication device (100) to update its reputation level.

Abstract: The invention relates to a method for granting access to a service provided by a connected device for a user having a user's device and requesting said access, the method comprising the steps of: receiving by the user's device from the connected device a request to validate a user profile, a user profile corresponding to a list of at least one data item representing the user's capabilities to use a service provided by the given connected device; requesting by the user's device to a verification server associated to the at least one data item to validate said data item, and receiving a digital signature of said data item generated by the verification server as a proof of the validation; transmitting the data item of the user profile and its digital signature to a device belonging to the owner of the connected device for it to be informed that said data item is validated, the user profile being considered as validated when the digital signatures of all the data items listed in the user profile are correctly ver

Abstract: The invention relates to a method for sending data to at least one device. According to the invention, a data sending control server sends to at least one data storage server at least one predetermined rule or a first request for sending data to at least one data processing server. The data storage server sends, based upon the at least one predetermined rule or the first request for sending data, data to the data processing server. The data sending control server sends to the data processing server a second request for sending to the device the data received or to be received by the data processing server. The data processing server sends, based upon the second request for sending the data, the received data to the at least one device.

Abstract: The invention relates to a method for managing the reputation level of a first communication device (100), said reputation level (103) being stored into a first secure enclave (102) embedded in said first communication device (100). The method comprises the steps of: receiving from the first communication device (100) by a second communication device (110) an information message; verifying that the information message is consistent with data obtained from a sensor embedded in the second communication device (110); generating a feedback message by the second communication device (110) to be transmitted to the first communication device (100) indicating if the information message is consistent for the secure enclave (102) of the first communication device (100) to update its reputation level.

Abstract: The disclosure provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X1, RA and R3 to R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The invention relates to a method for granting access to a service provided by a connected device for a user having a user's device and requesting said access, the method comprising the steps of: receiving by the user's device from the connected device a request to validate a user profile, a user profile corresponding to a list of at least one data item representing the user's capabilities to use a service provided by the given connected device; requesting by the user's device to a verification server associated to the at least one data item to validate said data item, and receiving a digital signature of said data item generated by the verification server as a proof of the validation; transmitting the data item of the user profile and its digital signature to a device belonging to the owner of the connected device for it to be informed that said data item is validated, the user profile being considered as validated when the digital signatures of all the data items listed in the user profile are correctly ver

Abstract: This invention relates to a method for anticipating the setup of a relation of trust between a first vehicle called central vehicle and at least a second vehicle, wherein two interaction areas are defined relatively to the position of the central vehicle, the first interaction area called exchange area comprising the central vehicle and the second interaction area called pre-authentication area being defined in a way that it has to be crossed by said second vehicle for it to enter into the exchange area, the method comprising the steps of: detecting if the second vehicle is localized in the pre-authentication area associated with the central vehicle; authenticating the central vehicle and the second vehicle if not already authenticated; upon successful authentication, providing the central vehicle and the second vehicle with at least one credential to set up the relation of trust for it to be already established when the second vehicle is present in the exchange area associated with the central vehicle.

Abstract: The invention relates to a method for sending data to at least one device. According to the invention, a data sending control server sends to at least one data storage server at least one predetermined rule or a first request for sending data to at least one data processing server. The data storage server sends, based upon the at least one predetermined rule or the first request for sending data, data to the data processing server. The data sending control server sends to the data processing server a second request for sending to the device the data received or to be received by the data processing server. The data processing server sends, based upon the second request for sending the data, the received data to the at least one device.

Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 and n are defined as in the description and in the claims. The compound of formula (I) can be for treating.

Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 and n are defined as in the description and in the claims. The compound of formula (I) can be for treating.

Abstract: The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.