Patents by Inventor Seble Wagaw

Seble Wagaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystaline forms of HCV inhibitor
    Patent number: 9469673
    Abstract: The present invention features crystalline forms of Compound I. In one embodiment, a crystalline form of Compound I has characteristic peaks in the PXRD pattern at values of two theta (° 2?) of 10.7, 11.6, 12.7, 13.0, 13.2, 13.7, 14.5, 18.7, 19.0, and 19.9 after equilibration at 43% relative humidity.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: October 18, 2016
    Assignee: AbbVie Inc.
    Inventors: Ahmad Y. Sheikh, Moiz Diwan, Agnes E. Pal, Yuchuan Gong, Paul J. Brackemeyer, Geoff Zhang, Seble Wagaw
  • CRYSTALINE FORMS OF HCV INHIBITOR
    Publication number: 20140018518
    Abstract: The present invention features crystalline forms of Compound I. In one embodiment, a crystalline form of Compound I has characteristic peaks in the PXRD pattern at values of two theta (° 2?) of 10.7, 11.6, 12.7, 13.0, 13.2, 13.7, 14.5, 18.7, 19.0, and 19.9 after equilibration at 43% relative humidity.
    Type: Application
    Filed: July 11, 2013
    Publication date: January 16, 2014
    Inventors: Ahmad Y. SHEIKH, Moiz DIWAN, Agnes E. PAL, Yuchuan GONG, Paul J. BRACKEMEYER, Geoff ZHANG, Seble WAGAW
  • Process for making macrocyclic oximyl hepatitis C protease inhibitors
    Patent number: 8193346
    Abstract: The present invention relates to a process for the preparation of macrocyclic compounds that are useful as hepatitis C virus (HCV) protease inhibitor compounds.
    Type: Grant
    Filed: December 4, 2008
    Date of Patent: June 5, 2012
    Assignee: Enanta Pharmaceuticals, Inc.
    Inventors: Seble Wagaw, Matthew Ravn, Kenneth Engstrom, Guoyou Xu, Zhe Wang, Ying Sun, Deqiang Niu, Yat Sun Or
  • PROCESS FOR MAKING MACROCYCLIC OXIMYL HEPATITIS C PROTEASE INHIBITORS
    Publication number: 20090156800
    Abstract: The present invention relates to a process for the preparation of macrocyclic compounds that are useful as hepatitis C virus (HCV) protease inhibitor compounds.
    Type: Application
    Filed: December 4, 2008
    Publication date: June 18, 2009
    Inventors: Seble Wagaw, Matthew Ravn, Kenneth Engstrom, Guoyou Xu, Zhe Wang, Ying Sun, Deqiang Niu, Yat Sun Or
  • Synthesis of (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile
    Publication number: 20080058528
    Abstract: A process for making (2S,5R)-5-ethynyl-1-{N-(4-methyl-1-(4-carboxy-pyridin-2-yl)piperidin-4-yl)glycyl}pyrrolidine-2-carbonitrile and salts thereof, and intermediates used in the process are disclosed.
    Type: Application
    Filed: July 19, 2007
    Publication date: March 6, 2008
    Inventors: Todd McDermott, Seble Wagaw, Kenneth Engstrom, Jorge Gandarilla, Albert Kruger, Michael Rozema, Michael Fickes, Steven Wittenberger, Lakshmi Bhagavatula, Thomas Borchardt
  • Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates
    Patent number: 6465693
    Abstract: A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed arylation or vinylation method, for the synthesis of indoles, carbazoles, and the like. The methods and strategies of the invention may be utilized in standard, parallel, and combinatorial synthetic protocols.
    Type: Grant
    Filed: January 18, 2001
    Date of Patent: October 15, 2002
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L. Buchwald, Seble Wagaw, O. Geis
  • Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates
    Publication number: 20010031894
    Abstract: A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed arylation or vinylation method, for the synthesis of indoles, carbazoles, and the like. The methods and strategies of the invention may be utilized in standard, parallel, and combinatorial synthetic protocols.
    Type: Application
    Filed: January 18, 2001
    Publication date: October 18, 2001
    Inventors: Stephen L. Buchwald, Seble Wagaw, Oliver Fabian Geis
  • Metal-catalyzed arylations of hydrazines, hydrazones, and related substrates
    Patent number: 6235936
    Abstract: A method is provided for the transition metal-catalyzed arylation, or vinylation, of hydrazines, hydrazones, and the like. Additionally, the invention provides a conceptually novel strategy, the cornerstone of which is the transition metal-catalyzed arylation or vinylation method, for the synthesis of indoles, carbazoles, and the like. The methods and strategies of the invention may be utilized in standard, parallel, and combinatorial synthetic protocols.
    Type: Grant
    Filed: February 26, 1998
    Date of Patent: May 22, 2001
    Assignee: Massachusetts Institute of Technology
    Inventors: Stephen L. Buchwald, Seble Wagaw, Oliver Fabian Geis