Patents by Inventor Seda Ayer

Seda Ayer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Therapeutic compositions and methods of making and using the same
    Patent number: 10717981
    Abstract: Disclosed herein are polynucleotide agents (including interfering RNA agents (RNAi)), small molecule agents, and synthetic cells, methods of making the same, and their use as therapeutics against age-related dysfunction and/or cellular dysfunction that results in various disease states. In some embodiments, one or more agents as disclosed herein can be used to target and/or decrease the expression of the paired-box protein 5 (PAX5) gene, protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F) gene, or both. Also disclosed herein are methods for the preparation and use of synthetic cells prepared by in vitro and/or in vivo manipulation using one or more cellular factors, polynucleotide agents, and/or small molecule agents. Disclosed herein is the use of these cells as therapeutic cells that treat age-related dysfunction and/or cellular dysfunction resulting in various disease states.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: July 21, 2020
    Assignee: Advanced ReGen Medical Technologies, LLC
    Inventors: Steven John Greco, Pranela Rameshwar, Khadidiatou Guiro, Seda Ayer
  • THERAPEUTIC COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20190218558
    Abstract: Disclosed herein are polynucleotide agents (including interfering RNA agents (RNAi)), small molecule agents, and synthetic cells, methods of making the same, and their use as therapeutics against age-related dysfunction and/or cellular dysfunction that results in various disease states. In some embodiments, one or more agents as disclosed herein can be used to target and/or decrease the expression of the paired-box protein 5 (PAX5) gene, protein phosphatase, Mg2+/Mn2+ dependent 1F (PPM1F) gene, or both. Also disclosed herein are methods for the preparation and use of synthetic cells prepared by in vitro and/or in vivo manipulation using one or more cellular factors, polynucleotide agents, and/or small molecule agents. Disclosed herein is the use of these cells as therapeutic cells that treat age-related dysfunction and/or cellular dysfunction resulting in various disease states.
    Type: Application
    Filed: January 17, 2019
    Publication date: July 18, 2019
    Inventors: Steven John Greco, Pranela Rameshwar, Khadidiatou Guiro, Seda Ayer