Patents by Inventor Sedide Ozturk

Sedide Ozturk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20240401241
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: June 12, 2024
    Publication date: December 5, 2024
    Inventors: Jan BERKA, Carolina DALLETT, Richard DANNEBAUM, Brian GODWIN, Seoyoung KIM, Jainee LEWIS, Khai LUONG, Sedide OZTURK, Joseph PLATZER, Florian RUBELT, Dilduz TELMAN
  • Immune profiling by primer extension target enrichment
    Patent number: 12043919
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: December 29, 2023
    Date of Patent: July 23, 2024
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Carolina Dallett, Richard Dannebaum, Brian Godwin, Seoyoung Kim, Jainee Lewis, Khai Luong, Sedide Ozturk, Joseph Platzer, Florian Rubelt, Dilduz Telman
  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20240125007
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: December 29, 2023
    Publication date: April 18, 2024
    Inventors: Jan BERKA, Carolina DALLETT, Richard DANNEBAUM, Brian GODWIN, Seoyoung KIM, Jainee LEWIS, Khai LUONG, Sedide OZTURK, Joseph PLATZER, Florian RUBELT, Dilduz TELMAN
  • Immuno-PETE
    Publication number: 20240102203
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: June 28, 2023
    Publication date: March 28, 2024
    Inventors: Jan BERKA, Brian GODWIN, Carolina DALLETT, Sedide OZTURK, Joseph PLATZER, Seoyoung KIM
  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20240026570
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: August 14, 2023
    Publication date: January 25, 2024
    Inventors: Jan BERKA, Carolina DALLETT, Richard DANNEBAUM, Brian GODWIN, Seoyoung KIM, Jainee LEWIS, Khai LUONG, Sedide OZTURK, Joseph PLATZER, Florian RUBELT, Dilduz TELMAN
  • WHOLE TRANSCRIPTOME ANALYSIS IN SINGLE CELLS
    Publication number: 20230416804
    Abstract: The invention is a method of single cell transcriptome analysis. The method comprises detecting multiple transcripts in each individual cell of the plurality of cells by barcoding the transcripts with a cell-specific compound barcode formed using a DNA polymerase and a terminal transferase, optionally in a single enzyme such as a reverse transcriptase.
    Type: Application
    Filed: May 26, 2023
    Publication date: December 28, 2023
    Inventors: Sedide Ozturk, Martin Ranik, Florian Rubelt
  • PRIMER EXTENSION TARGET ENRIGHMENT AND IMPROVEMENTS THERETO INCLUDING SIMULTANEOUS ENRICHMENT OF DNA AND RNA
    Publication number: 20230357830
    Abstract: The present invention is a method and compositions for primer extension target enrichment of nucleic acids and improvements thereto including simultaneously enriching for RNA and DNA and optionally sequencing the enriched products.
    Type: Application
    Filed: October 12, 2022
    Publication date: November 9, 2023
    Inventors: Brian Christopher Godwin, Sedide Ozturk
  • SPATIAL ANALYSIS OF MULTIPLE TARGETS IN TISSUE SAMPLES
    Publication number: 20230340578
    Abstract: The invention provides methods and compositions for analysis of single cell in tissue sample allowing for simultaneous detection and localization of multiple targets in the cells.
    Type: Application
    Filed: July 8, 2021
    Publication date: October 26, 2023
    Inventors: Jan BERKA, Dieter HEINDL, Sedide OZTURK, Nikolaus-Peter STENGELE
  • Immune profiling by primer extension target enrichment
    Patent number: 11773511
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: August 18, 2020
    Date of Patent: October 3, 2023
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Carolina Dallett, Richard Dannebaum, Brian Godwin, Seoyoung Kim, Jainee Lewis, Khai Luong, Sedide Ozturk, Joseph Platzer, Florian Rubelt, Dilduz Telman
  • Immuno-PETE
    Patent number: 11725307
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: May 4, 2021
    Date of Patent: August 15, 2023
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Brian Godwin, Carolina Dallett, Sedide Ozturk, Joseph Platzer, Seoyoung Kim
  • System for identification of antigens recognized by T cell receptors expressed on tumor infiltrating lymphocytes
    Patent number: 11603565
    Abstract: The invention is a method of identifying a cognate antigen for a T-cell receptor using neoantigens from a patient's tumor cells combined with the patient's T-cells and using cell sorting, genome sequencing, expressing TCR genes, presenting tumor neoantigens on MHC complex and uniquely barcoding the T-cells where TCR recognition occurs to tag all components of the TCR recognition complex.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: March 14, 2023
    Assignees: ROCHE SEQUENCING SOLUTIONS, INC., VENTANA MEDICAL SYSTEMS, INC.
    Inventors: Nelson R. Alexander, Aoune Barhoumi, Jan Berka, Rui Chen, Lisa L. Gallegos, Toumy Guettouche, Seoyoung Kim, Maeve E. O'Huallachain, Sedide Ozturk, Jigar Patel, Florian Rubelt, Stacey Stanislaw
  • Primer extension target enrichment and improvements thereto including simultaneous enrichment of DNA and RNA
    Patent number: 11499180
    Abstract: The present invention is a method and compositions for primer extension target enrichment of nucleic acids and improvements thereto including simultaneously enriching for RNA and DNA and optionally sequencing the enriched products. An embodiment of the present invention includes a method comprising the steps of: hybridizing a target-specific primer to a target DNA or RNA, wherein the primer comprises a target-binding region and a region of complementarity to an adaptor; extending the primer with a DNA polymerase or reverse transcriptase to form a primer extension product; contacting the product with an adaptor comprising a longer strand with a 5?-overhang having complementarity to said primer and a shorter strand comprising a universal priming site; hybridizing the adaptor to the product; and ligating one strand of the adaptor to the product to form a ligation product.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: November 15, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Brian Christopher Godwin, Sedide Ozturk
  • WHOLE TRANSCRIPTOME ANALYSIS IN SINGLE CELLS
    Publication number: 20220177950
    Abstract: The invention is a method of single cell transcriptome analysis. The method comprises detecting multiple transcripts in each individual cell of the plurality of cells by barcoding the transcripts with a cell-specific compound barcode formed using a DNA polymerase and a terminal transferase, optionally in a single enzyme such as a reverse transcriptase.
    Type: Application
    Filed: December 3, 2020
    Publication date: June 9, 2022
    Inventors: Martin Ranik, Florian Rubelt, Sedide Ozturk
  • Immuno-PETE
    Patent number: 11306356
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: April 19, 2022
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Brian Godwin, Carolina Dallett, Sedide Ozturk, Joseph Platzer, Seoyoung Kim
  • A SYSTEM FOR IDENTIFICATION OF ANTIGENS RECOGNIZED BY T CELL RECEPTORS EXPRESSED ON TUMOR INFILTRATING LYMPHOCYTES
    Publication number: 20210285049
    Abstract: The invention is a method of identifying a cognate antigen for a T-cell receptor using neoantigens from a patient's tumor cells combined with the patient's T-cells and using cell sorting, genome sequencing, expressing TCR genes, presenting tumor neoantigens on MHC complex and uniquely barcoding the T-cells where TCR recognition occurs to tag all components of the TCR recognition complex.
    Type: Application
    Filed: June 14, 2019
    Publication date: September 16, 2021
    Inventors: Nelson R. Alexander, Aoune Barhoumi, Jan Berka, Rui Chen, Lisa L. Gallegos, Toumy Guettouche, Seoyoung Kim, Maeve E. O'Huallachain, Sedide Ozturk, Jigar Patel, Florian Rubelt, Stacey Stanislaw
  • Immuno-PETE
    Patent number: 11098360
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: August 24, 2021
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Jan Berka, Brian Godwin, Carolina Dallett, Sedide Ozturk, Joseph Platzer, Seoyoung Kim
  • Immuno-PETE
    Publication number: 20210254157
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: May 4, 2021
    Publication date: August 19, 2021
    Inventors: Jan BERKA, Brian GODWIN, Carolina DALLETT, Sedide OZTURK, Joseph PLATZER, Seoyoung KIM
  • IMMUNE PROFILING BY PRIMER EXTENSION TARGET ENRICHMENT
    Publication number: 20210172015
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: August 18, 2020
    Publication date: June 10, 2021
    Inventors: Jan Berka, Carolina Dallett, Richard Dannebaum, Brian Godwin, Seoyoung Kim, Jainee Lewis, Khai Luong, Sedide Ozturk, Joseph Platzer, Florian Rubelt, Dilduz Telman
  • Immuno-PETE
    Publication number: 20200385707
    Abstract: Methods and compositions are described herein for primer extension target enrichment of immune receptor (BCR or TCR) sequences.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 10, 2020
    Inventors: Jan BERKA, Brian GODWIN, Carolina DALLETT, Sedide OZTURK, Joseph PLATZER, Seoyoung KIM
  • METHODS OF IDENTIFYING MULTIPLE EPITOPES IN CELLS
    Publication number: 20200157603
    Abstract: The invention provides methods, compositions, kits and devices for the detection of target molecules. In some embodiments, the invention allows for multiplexed target molecule detection.
    Type: Application
    Filed: November 21, 2019
    Publication date: May 21, 2020
    Inventors: Maeve O'Huallachain, Carolina Dallett, Sedide Ozturk, Florian Rubelt, Sri Ramakrishna Paladugu, Razika Hussein, Garry P. Nolan