Patents by Inventor Seetharamaiah Sethy S. Naremaddepalli

Seetharamaiah Sethy S. Naremaddepalli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DUAL INHIBITORS OF TIM-3 AND PD-1 PATHWAYS
    Publication number: 20200368210
    Abstract: The present disclosure relates to 3-substituted 1,2,4-oxadiazole compounds and their derivatives, which are useful as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3) inhibitors or as dual inhibitors of TIM-3 and the programmed cell death 1 (PD-1) signaling pathway. The disclosure also relates to treatment of disorders by inhibiting an immunosuppressive signal induced by TIM-3, PD-1, PD-L1, and/or PD-L2.
    Type: Application
    Filed: October 31, 2018
    Publication date: November 26, 2020
    Inventors: Pottayil Govindan N. Sasikumar, Muralidhara Ramachandra, Seetharamaiah Sethy S. Naremaddepalli, Nagaraj Gowda