Patents by Inventor Sei Ryang Oh

Sei Ryang Oh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12390505
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating obesity or diabetes, and to a food composition and feed composition for preventing or alleviating obesity or diabetes, comprising as an active ingredient, an Acanthopanax extract, a Garcinia cambogia extract, or compounds isolated therefrom. The composition has synergistic antidiabetic and antiobesity activity compared to that of using only an Acanthopanax extract, a Garcinia cambogia extract, or compounds isolated therefrom. Therefore, it is possible to reduce the possibility of any side effects that may be caused by an overdose of or long-term administration of the Garcinia cambogia extract and a substance isolated therefrom, and thus the composition can be very effectively utilized in the development of a therapeutic agent for diabetes or obesity.
    Type: Grant
    Filed: August 18, 2021
    Date of Patent: August 19, 2025
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Su Ui Lee, Hyung Won Ryu, Mun Ock Kim, Sei Ryang Oh, Doo Young Kim, Hyun Jae Jang
  • Publication number: 20230364170
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating obesity or diabetes, and to a food composition and feed composition for preventing or alleviating obesity or diabetes, comprising as an active ingredient, an Acanthopanax extract, a garcinia cambogia extract, or compounds isolated therefrom. The composition has synergistic antidiabetic and antiobesity activity compared to that of using only an Acanthopanax extract, a garcinia cambogia extract, or compounds isolated therefrom. Therefore, it is possible to reduce the possibility of any side effects that may be caused by an overdose of or long-term administration of the garcinia cambogia extract and a substance isolated therefrom, and thus the composition can be very effectively utilized in the development of a therapeutic agent for diabetes or obesity.
    Type: Application
    Filed: August 18, 2021
    Publication date: November 16, 2023
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Su Ui LEE, Hyung Won RYU, Mun Ock KIM, Sei Ryang OH, Doo Young KIM, Hyun Jae JANG
  • Patent number: 10751378
    Abstract: The present invention relates to a composition for suppressing chronic obstructive pulmonary disease (COPD) comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom and, more particularly, to a pharmaceutical composition for preventing or treating COPD comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom; a food composition for preventing or improving COPD, and the compound isolated therefrom. The composition comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom, according to the present invention, is not toxic, suppresses the invasion of inflammatory cells into the bronchial tube of a COPD-induced animal model, and effectively suppresses the expression of CXCL-1, TNF-?, or MIP-2.
    Type: Grant
    Filed: April 17, 2015
    Date of Patent: August 25, 2020
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Sei Ryang Oh, Kyung Seop Ahn, Seung Hyung Kim, In Sik Shin, Hang Jin, Jung Hee Kim, Hyung Won Ryu, Wan Yi Li, Sang Woo Lee, Joong Ku Lee, Sang Ho Choi
  • Patent number: 10413579
    Abstract: The present invention relates to a composition for preventing or treating asthma comprising a Pistacia weinmannifolia J. Poiss. ex Franch extract or a fraction thereof. The Pistacia weinmannifolia J. Poiss. ex Franch extract or the fraction thereof according to the present invention does not exhibit toxicity, inhibits the generation of NO, IL-4, IL-5, and IL-13 and the generation of reactive oxygen species in the bronchial tubes, and has significantly induced the alleviation of airway hyperresponsiveness, inhibition of the infiltration of inflammatory cells into the bronchial tubes, and reduction of inflammatory cells in bronchoalveolar lavage fluid in an ovalbumin-induced asthma mouse model. In addition, the Pistacia weinmannifolia J. Poiss.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: September 17, 2019
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Kyung Seop Ahn, Sei Ryang Oh, Ok Kyoung Kwon, In Sik Shin, Hyung Won Ryu, Sang Woo Lee, Joong Ku Lee, Hyeong Kyu Lee, Sang Ho Choi, Doo Young Kim, Jung Hee Kim, Li Wan Yi, Jin Hang
  • Patent number: 10172816
    Abstract: A composition comprising a purified extract isolated from Pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient or the compounds isolated therefrom as an active ingredient for treating a chronic obstructive pulmonary disease and the use thereof. Inventive purified extract and compounds showed potent anti-COPD activity without beta-2-receptor agonistic response through various in vivo tests as well as in vitro test. Therefore, it can be used as the therapeutics or functional health food for treating and preventing chronic obstructive pulmonary disease (COPD).
    Type: Grant
    Filed: December 19, 2016
    Date of Patent: January 8, 2019
    Assignees: YUNGJIN PHARMACEUTICAL CO., LTD, KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Yongnam Lee, Ji-seok Yoo, Dae-hee Shin, Byung-hwan Ryoo, Kyung Seop Ahn, Sei Ryang Oh, Hyeong Kyu Lee, In Sik Shin, Doo Young Kim, Ok-Kyoung Kwon, Hyuk Hwan Song, Seung Hyung Kim, SuUi Lee
  • Patent number: 10092587
    Abstract: The present invention relates to an antiviral composition comprising any one selected from the group consisting of chlorine, phosphocholine, cytidine triphosphate, CDP-choline, phosphorylcholine, and phosphatidylcholine. The antiviral composition is harmless to the human body and exhibits an excellent inhibitory effect on virus proliferation. Therefore, it can be applied to a pharmaceutical composition for preventing or treating viral diseases as well as a health functional food, a quasi-drug composition, and a feed composition for preventing or ameliorating viral diseases.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: October 9, 2018
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Dur Han Kwon, Mi Jin Jang, Jae Hyoung Song, Gansukh Enkhtaivan, Sei Ryang Oh
  • Patent number: 10058527
    Abstract: The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.
    Type: Grant
    Filed: August 18, 2014
    Date of Patent: August 28, 2018
    Assignees: ENZYCHEM LIFESCIENCES CORPORATION, KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jae Wha Kim, Sei Ryang Oh, Kyung Seop Ahn, Ho Bum Kang, Jae Min Shin, Young Eun Ko, Tae Suk Lee, Myung Hwan Kim, Jong Koo Kang, Yong-Hae Han, Ki-Young Sohn
  • Patent number: 9895337
    Abstract: The invention relates to pharmaceutical compositions, as well as health functional food compositions and quasi-drug compositions, for preventing, treating, or improving rheumatoid arthritis, comprising a monoacetyldiacylglycerol compound as an active ingredient. The monoacetyldiacylglycerol of the invention is effective in inhibiting the phosphorylation of STAT-3 known to be a therapeutic target for rheumatoid arthritis. As the monoacetyldiacylglycerol is an effective therapeutic agent without toxicity, the monoacetyldiacylglycerol can overcome the side effects of the medicines currently used in the treatment of rheumatoid arthritis. Thus, the monoacetyldiacylglycerol can be used for preventing, treating or improving rheumatoid arthritis.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: February 20, 2018
    Assignees: Enzychem Lifesciences Corporation, Korea Research Institute of Bioscience and Biotechnology
    Inventors: Jae Wha Kim, Sei Ryang Oh, Kyung Seop Ahn, Ho Bum Kang, Beom Su Park, Tae Suk Lee, Jong Koo Kang, Young Sik Jung, Ki-Young Sohn
  • Patent number: 9820963
    Abstract: The present invention relates to a pharmaceutical composition for preventing, ameliorating, or treating cancer. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating cancer including a lignan compound having a specific chemical structure (Chemical Formula 1); a health functional food composition for preventing or ameliorating cancer including the lignan compound; and a method for preventing, ameliorating, or treating cancer using the composition. Further, the present invention relates to a use of the lignan compound in the preparation of a pharmaceutical composition or a health functional food composition for preventing, ameliorating, or treating cancer.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: November 21, 2017
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Sei Ryang Oh, Yong Yeon Cho, Hyung Won Ryu, Cheol Jung Lee, Hye Suk Lee, Doo Young Kim, Jung Hee Kim, Kyung Seop Ahn, Mee Hyun Lee, Hyeong Kyu Lee
  • Publication number: 20170266142
    Abstract: A composition comprising a purified extract isolated from Pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient or the compounds isolated therefrom as an active ingredient for treating a chronic obstructive pulmonary disease and the use thereof. Inventive purified extract and compounds showed potent anti-COPD activity without beta-2-receptor agonistic response through various in vivo tests as well as in vitro test. Therefore, it can be used as the therapeutics or functional health food for treating and preventing chronic obstructive pulmonary disease (COPD).
    Type: Application
    Filed: December 19, 2016
    Publication date: September 21, 2017
    Inventors: Yongnam LEE, Ji-seok YOO, Dae-hee SHIN, Byung-hwan RYOO, Kyung Seop AHN, Sei Ryang OH, Hyeong Kyu LEE, In Sik SHIN, Doo Young KIM, Ok-Kyoung KWON, Hyuk Hwan SONG, Seung Hyung KIM, SuUi LEE
  • Publication number: 20170173095
    Abstract: The present invention relates to a composition for preventing or treating asthma comprising a Pistacia weinmannifolia J. Poiss. ex Franch extract or a fraction thereof. The Pistacia weinmannifolia J. Poiss. ex Franch extract or the fraction thereof according to the present invention does not exhibit toxicity, inhibits the generation of NO, IL-4, IL-5, and IL-13 and the generation of reactive oxygen species in the bronchial tubes, and has significantly induced the alleviation of airway hyperresponsiveness, inhibition of the infiltration of inflammatory cells into the bronchial tubes, and reduction of inflammatory cells in bronchoalveolar lavage fluid in an ovalbumin-induced asthma mouse model. In addition, the Pistacia weinmannifolia J. Poiss.
    Type: Application
    Filed: July 1, 2014
    Publication date: June 22, 2017
    Inventors: Kyung Seop Ahn, Sei Ryang Oh, Ok Kyoung Kwon, In Sik Shin, Hyung Won Ryu, Sang Woo Lee, Joong Ku Lee, Hyeong Kyu Lee, Sang Ho Choi, Doo Young Kim, Jung Hee Kim, Li Wan Yi, Jin Hang
  • Publication number: 20170173065
    Abstract: The present invention relates to an antiviral composition comprising any one selected from the group consisting of chlorine, phosphocholine, cytidine triphosphate, CDP-choline, phosphorylcholine, and phosphatidylcholine. The antiviral composition is harmless to the human body and exhibits an excellent inhibitory effect on virus proliferation. Therefore, it can be applied to a pharmaceutical composition for preventing or treating viral diseases as well as a health functional food, a quasi-drug composition, and a feed composition for preventing or ameliorating viral diseases.
    Type: Application
    Filed: December 22, 2016
    Publication date: June 22, 2017
    Applicant: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Dur Han Kwon, Mi Jin Jang, Jae Hyoung Song, Gansukh Enkhtaivan, Sei Ryang Oh
  • Patent number: 9655871
    Abstract: A composition comprising a purified extract isolated from Pseudolysimachion rotundum var. subintegrum containing abundant amount of active ingredient or the compounds isolated therefrom as an active ingredient for treating a chronic obstructive pulmonary disease and the use thereof. Inventive purified extract and compounds showed potent anti-COPD activity without beta-2-receptor agonistic response through various in vivo tests as well as in vitro test. Therefore, it can be used as the therapeutics or functional health food for treating and preventing chronic obstructive pulmonary disease (COPD).
    Type: Grant
    Filed: April 9, 2014
    Date of Patent: May 23, 2017
    Assignees: YUNGJIN PHARMACEUTICAL CO., LTD., KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Yongnam Lee, Ji-seok Yoo, Dae-hee Shin, Byung-hwan Ryoo, Kyung Seop Ahn, Sei Ryang Oh, Hyeong Kyu Lee, In Sik Shin, Doo Young Kim, Ok-Kyoung Kwon, Hyuk Hwan Song, Seung Hyung Kim, SuUi Lee
  • Patent number: 9610310
    Abstract: The present invention relates to a pharmaceutical composition for preventing or treating inflammatory diseases or asthma comprising a Lagerstroemia ovalifolia extract or a fraction thereof as an active ingredient, and a health functional food and a feed additive for preventing or improving inflammatory diseases or asthma comprising the extract or the fraction as an active ingredient.
    Type: Grant
    Filed: December 28, 2012
    Date of Patent: April 4, 2017
    Assignee: Korea Research Institute of Bioscience and Biotechnology
    Inventors: Kyung Seop Ahn, Sei Ryang Oh, Ok Kyoung Kwon, Fifit Juniarti, Rifatul Widjhati, Ji Won Park, Jin Hyub Paik, Joong Ku Lee, Hyeong Kyu Lee, Sang Ho Choi
  • Publication number: 20170035822
    Abstract: The present invention relates to a composition for suppressing chronic obstructive pulmonary disease (COPD) comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom and, more particularly, to a pharmaceutical composition for preventing or treating COPD comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom; a food composition for preventing or improving COPD, and the compound isolated therefrom. The composition comprising a Pistacia weinmannifolia extract, a fraction thereof, or a compound isolated therefrom, according to the present invention, is not toxic, suppresses the invasion of inflammatory cells into the bronchial tube of a COPD-induced animal model, and effectively suppresses the expression of CXCL-1, TNF-?, or MIP-2.
    Type: Application
    Filed: April 17, 2015
    Publication date: February 9, 2017
    Inventors: Sei Ryang OH, Kyung Seop AHN, Seung Hyung KIM, In Sik SHIN, Hang JIN, Jung Hee KIM, Hyung Won RYU, Wan Yi LI, Sang Woo LEE, Joong Ku LEE, Sang Ho CHOI
  • Patent number: 9481630
    Abstract: The present invention relates to an injenane-type diterpene compound derived from Euphorbia kansui Liou, and a pharmaceutical composition for treating or preventing viral infectious diseases, a health functional food for preventing or ameliorating viral infectious diseases and a composition for enhancing the production of interferon-gamma, which comprise the injenane-type diterpene compound. Furthermore, the present invention relates to a method for preventing or treating viral infectious diseases including administering the composition to a subject having a viral infectious disease occurrence or a risk thereof with a therapeutically effective dose.
    Type: Grant
    Filed: September 28, 2012
    Date of Patent: November 1, 2016
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Sei Ryang Oh, Jae Wha Kim, Hyeong Kyu Lee, Piseth Khiev, Doo Young Kim, Jung Hee Kim, Jae Sung Song, Kyung Seop Ahn
  • Publication number: 20160256428
    Abstract: The present invention relates to a composition containing a monoacetyldiglyceride compound as an active ingredient, for inhibiting blood cancer or metastasis, and a use thereof. The monoacetyldiglyceride compound according to the present invention has excellent effects of inhibiting the expression of IL-4 and inhibiting the activity of STAT-6, and thereby is capable of overcoming side effects of currently used blood cancer or metastasis inhibiting agents. Also, the monoacetyldiglyceride compound is a non-toxic compound having superior therapeutic effects and thus can be useful as a composition for preventing, treating, or improving blood cancer and metastasis.
    Type: Application
    Filed: August 18, 2014
    Publication date: September 8, 2016
    Inventors: Jae Wha Kim, Sei Ryang Oh, Kyung Seop Ahn, Ho Bum Kang, Jae Min Shin, Young Eun Ko, Tae Suk Lee, Myung Hwan Kim, Jong Koo Kang, Yong-Hae Han, Ki-Young Sohn
  • Patent number: 9428520
    Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of Daphne genkwa, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of Daphne genkwa, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.
    Type: Grant
    Filed: May 17, 2012
    Date of Patent: August 30, 2016
    Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Jae Wha Kim, Kyung Seop Ahn, Ho Bum Kang, Sei Ryang Oh, Jae Jong Go, Joo Heon Kim, Jang Mi Sun, Jae Sung Song, Hyun Woo Oh, Da Jung Ji
  • Publication number: 20160228402
    Abstract: The present invention relates to a pharmaceutical composition for preventing, ameliorating, or treating cancer. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating cancer including a lignan compound having a specific chemical structure (Chemical Formula 1); a health functional food composition for preventing or ameliorating cancer including the lignan compound; and a method for preventing, ameliorating, or treating cancer using the composition. Further, the present invention relates to a use of the lignan compound in the preparation of a pharmaceutical composition or a health functional food composition for preventing, ameliorating, or treating cancer.
    Type: Application
    Filed: November 8, 2013
    Publication date: August 11, 2016
    Applicant: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
    Inventors: Sei Ryang OH, Yong Yeon CHO, Hyung Won RYU, Cheol Jung LEE, Hye Suk LEE, Doo Young KIM, Jung Hee KIM, Kyung Seop AHN, Mee Hyun LEE, Hyeong Kyu LEE
  • Publication number: 20160199338
    Abstract: The invention relates to pharmaceutical compositions, as well as health functional food compositions and quasi-drug compositions, for preventing, treating, or improving rheumatoid arthritis, comprising a monoacetyldiacylglycerol compound as an active ingredient. The monoacetyldiacylglycerol of the invention is effective in inhibiting the phosphorylation of STAT-3 known to be a therapeutic target for rheumatoid arthritis. As the monoacetyldiacylglycerol is an effective therapeutic agent without toxicity, the monoacetyldiacylglycerol can overcome the side effects of the medicines currently used in the treatment of rheumatoid arthritis. Thus, the monoacetyldiacylglycerol can be used for preventing, treating or improving rheumatoid arthritis.
    Type: Application
    Filed: August 18, 2014
    Publication date: July 14, 2016
    Inventors: Jae Wha KIM, Sei Ryang OH, Kyung Seop AHN, Ho Bum KANG, Beom Su PARK, Tae Suk LEE, Jong Koo KANG, Young Sik JUNG, Yong-Hae HAN, Ki-Young SOHN