Patents by Inventor Seigo Izumo

Seigo Izumo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Use of Deacetylase Inhibitors
    Publication number: 20090012066
    Abstract: The present invention provides methods of treating and/or preventing pathologic cardiac hypertrophy and heart failure comprising administering hydroxamate compounds which are deacetylase inhibitors.
    Type: Application
    Filed: August 9, 2006
    Publication date: January 8, 2009
    Inventors: Seigo Izumo, Suraj Shivappa Shetty
  • Use Of Rapamycin Derivatives For The Treatment And/Or Prevention Of Cardiovas Cular Disorders
    Publication number: 20080214595
    Abstract: The present invention provides methods of treating and/or preventing cardiovascular disorders comprising administering rapamycin derivative compounds.
    Type: Application
    Filed: May 15, 2006
    Publication date: September 4, 2008
    Inventors: Seigo Izumo, Stefan Edwin Hardt
  • Cardiac-cell specific enhancer elements and uses thereof
    Publication number: 20040260079
    Abstract: The invention features cardiac cell-specific enhancer elements derived from Csx/Nkx2.5 regulatory regions. These enhancer elements are useful, for example, for (i) regulating gene expression in cardiac cells, (ii) inducing stem cells (e.g., embryonic stem cells or bone marrow stem cells) to differentiate as cardiomyocytes, and (iii) identifying factors that induce the differentiation of stem cells as cardiomyocytes.
    Type: Application
    Filed: February 17, 2004
    Publication date: December 23, 2004
    Inventors: Ike W. Lee, Seigo Izumo
  • Cardiac-cell specific enhancer elements and uses thereof
    Patent number: 6818757
    Abstract: The invention features cardiac cell-specific enhancer elements derived from Csx/Nkx2.5 regulatory regions. These enhancer elements are useful, for example, for (i) regulating gene expression in cardiac cells, (ii) inducing stem cells (e.g., embryonic stem cells or bone marrow stem cells) to differentiate as cardiomyocytes, and (iii) identifying factors that induce the differentiation of stem cells as cardiomyocytes.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: November 16, 2004
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Ike W. Lee, Seigo Izumo
  • Cardiac-cell specific enhancer elements and uses thereof
    Publication number: 20020022259
    Abstract: The invention features cardiac cell-specific enhancer elements derived from Csx/Nkx2.5 regulatory regions. These enhancer elements are useful, for example, for (i) regulating gene expression in cardiac cells, (ii) inducing stem cells (e.g., embryonic stem cells or bone marrow stem cells) to differentiate as cardiomyocytes, and (iii) identifying factors that induce the differentiation of stem cells as cardiomyocytes.
    Type: Application
    Filed: January 16, 2001
    Publication date: February 21, 2002
    Inventors: Ike W. Lee, Seigo Izumo