Abstract: An endoscope holding device includes an insertion part that is long and holds the distal end part of an endoscope so as to freely protrude and retract; a distal end face that specifies a protruding direction of the endoscope, and is formed at the distal end of the insertion part, a displacement part which has a displacement face that is curved from the distal end toward a proximal end and provided at a position apart from the distal end face in order to displace living body tissue in front of the insertion part to secure a space for operating the distal end part of the endoscope protruded from the distal end face to curve; and a fixing portion that fixes the displacement part and the insertion part such that the distal end side of the displacement face intersects a direction orthogonal to the distal end face.

Abstract: The present application relates to a biological tissue transfer method for transferring a biological target tissue within the body, the method comprising: (a) attaching part of a first traction member to a first position which is different from a connecting position at which the target tissue is connected to other biological tissue; (b) attaching part of a second traction member to a second position which serves as the apex of a triangle formed together with the connecting position and the first position that surrounds the target site; (c) extending the first traction member in the direction from the connecting position to the first position, and extending the second traction member in the direction from the connecting position to the second position; and (d) transferring the target tissue within the body by applying traction on the first traction member and the second traction member respectively.

Abstract: An endoscope holding device includes an insertion part that is long and holds the distal end part of an endoscope so as to freely protrude and retract; a distal end face that specifies a protruding direction of the endoscope, and is formed at the distal end of the insertion part, a displacement part which has a displacement face that is curved from the distal end toward a proximal end and provided at a position apart from the distal end face in order to displace living body tissue in front of the insertion part to secure a space for operating the distal end part of the endoscope protruded from the distal end face to curve; and a fixing portion that fixes the displacement part and the insertion part such that the distal end side of the displacement face intersects a direction orthogonal to the distal end face.

Abstract: An organ displacing method implemented for performing a procedure in a patient's body cavity, the method includes a gravitational movement step in which the body position of the patient is changed, whereby surrounding organs adjacent to a hollow organ are moved in a primary direction by gravity; and a non-gravitational movement step in which, by using a medical instrument inserted into the hollow organ, the hollow organ is moved in a secondary direction where the hollow organ is separated from the surrounding organs.

Abstract: The present application relates to a biological tissue transfer method for transferring a biological target tissue within the body, the method comprising: (a) attaching part of a first traction member to a first position which is different from a connecting position at which the target tissue is connected to other biological tissue; (b) attaching part of a second traction member to a second position which serves as the apex of a triangle formed together with the connecting position and the first position that surrounds the target site; (c) extending the first traction member in the direction from the connecting position to the first position, and extending the second traction member in the direction from the connecting position to the second position; and (d) transferring the target tissue within the body by applying traction on the first traction member and the second traction member respectively.

Abstract: A composition for gene therapy, comprising IL-12 gene and a nucleic acid carrier, wherein the nucleic acid carrier comprises a polypeptide consisting of diaminobutyric acid and/or a pharmaceutically acceptable salt thereof is prepared, and the composition is delivered to target cells to allow the cells to express IL-12 gene and produce IL-12, which increase a therapeutic effect.