Patents by Inventor Seiichi P. T. Matsuda

Seiichi P. T. Matsuda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • levopimaradiene synthase
    Patent number: 7374920
    Abstract: The present invention is directed to nucleic acid sequences of Ginkgo biloba diterpene synthases, particularly of a levopimaradiene synthase. More specifically, the invention is directed to a cell of a unicellular organism, such as Saccharomyces cerevisiae or Escherichia coli, comprising levopimaradiene synthase for the metabolically engineered in vivo biosynthesis of a diterpene and a ginkgolide.
    Type: Grant
    Filed: June 24, 2005
    Date of Patent: May 20, 2008
    Assignee: William Marsh Rice University
    Inventors: Seiichi P. T. Matsuda, Hala G. Schepmann
  • Diterpene-producing unicellular organism
    Patent number: 7238514
    Abstract: The present invention is directed to a unicellular organism system, such as a yeast, for producing geranylgeranyl pyrophosphate and a diterpene in vivo. The yeast cell preferably comprises an inducible nucleic acid sequence encoding geranylgeranyl pyrophosphate synthase, an inducible nucleic acid sequence encoding a soluble form of HMG-CoA reductase, a nucleic acid sequence of an allele that confers an increase in sterol metabolic flux and, in the diterpene-producing cell, a diterpene synthase.
    Type: Grant
    Filed: January 7, 2002
    Date of Patent: July 3, 2007
    Assignee: William Marsh Rice University
    Inventors: Seiichi P. T. Matsuda, Elizabeth A. Hart
  • Ginkgo biloba levopimaradiene synthase
    Patent number: 6946283
    Abstract: The present invention is directed to nucleic acid sequences of Ginkgo biloba diterpene synthases, particularly of a levopimaradiene synthase. More specifically, the invention is directed to a cell of a unicellular organism, such as Saccharomyces cerevisiae or Escherichia coli, comprising levopimaradiene synthase for the metabolically engineered in vivo biosynthesis of a diterpene and a ginkgolide.
    Type: Grant
    Filed: January 7, 2002
    Date of Patent: September 20, 2005
    Assignee: William Marsh Rice University
    Inventors: Seiichi P. T. Matsuda, Hala G. Schepmann
  • Diterpene-producing unicellular organism
    Publication number: 20040072323
    Abstract: The present invention is directed to a unicellular organism system, such as a yeast, for producing geranylgeranyl pyrophosphate and a diterpene in vivo. The yeast cell preferably comprises an inducible nucleic acid sequence encoding geranylgeranyl pyrophosphate synthase, an inducible nucleic acid sequence encoding a soluble form of HMG-CoA reductase, a nucleic acid sequence of an allele that confers an increase in sterol metabolic flux and, in the diterpene-producing cell, a diterpene synthase.
    Type: Application
    Filed: January 7, 2002
    Publication date: April 15, 2004
    Inventors: Seiichi P.T. Matsuda, Elizabeth A. Hart
  • Ginkgo biloba levopimaradiene synthase
    Publication number: 20020164736
    Abstract: The present invention is directed to nucleic acid sequences of Ginkgo biloba diterpene synthases, particularly of a levopimaradiene synthase. More specifically, the invention is directed to a cell of a unicellular organism, such as Saccharomyces cerevisiae or Escherichia coli, comprising levopimaradiene synthase for the metabolically engineered in vivo biosynthesis of a diterpene and a ginkgolide.
    Type: Application
    Filed: January 7, 2002
    Publication date: November 7, 2002
    Inventors: Seiichi P.T. Matsuda, Hala G. Schepmann