Patents by Inventor Seiichi Uchiyama
Seiichi Uchiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11649311Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: GrantFiled: December 13, 2018Date of Patent: May 16, 2023Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu Tsuji, Kumiko Ikado, Seiichi Uchiyama, Kyoko Kawamoto
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Patent number: 11452697Abstract: An intracellular delivery vehicle of which surface is covered by a positive charge, an intracellular delivery complex in which a component or compound desired is loaded in the intracellular delivery vehicle, a temperature-sensitive probe comprising the intracellular delivery complex, and a method for measuring the intracellular temperature by the temperature-sensitive probe are disclosed. The intracellular delivery vehicle is useful on account of its capability of easily delivering the component or compound desired inside the cell without inhibiting cell proliferation.Type: GrantFiled: June 12, 2020Date of Patent: September 27, 2022Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITYInventors: Toshikazu Tsuji, Kumiko Ikado, Sayuri Yamada, Seiichi Uchiyama, Kyoko Kawamoto, Hidetoshi Tokuyama, Kentaro Okano
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Patent number: 11199537Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: GrantFiled: December 13, 2018Date of Patent: December 14, 2021Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu Tsuji, Kumiko Ikado, Seiichi Uchiyama, Kyoko Kawamoto
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Publication number: 20200309782Abstract: An intracellular delivery vehicle of which surface is covered by a positive charge, an intracellular delivery complex in which a component or compound desired is loaded in the intracellular delivery vehicle, a temperature-sensitive probe comprising the intracellular delivery complex, and a method for measuring the intracellular temperature by the temperature-sensitive probe are disclosed. The intracellular delivery vehicle is useful on account of its capability of easily delivering the component or compound desired inside the cell without inhibiting cell proliferation.Type: ApplicationFiled: June 12, 2020Publication date: October 1, 2020Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITYInventors: Toshikazu Tsuji, Kumiko Ikado, Sayuri Yamada, Seiichi Uchiyama, Kyoko Kawamoto, Hidetoshi Tokuyama, Kentaro Okano
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Patent number: 10712346Abstract: An intracellular delivery vehicle of which surface is covered by a positive charge, an intracellular delivery complex in which a component or compound desired is loaded in the intracellular delivery vehicle, a temperature-sensitive probe comprising the intracellular delivery complex, and a method for measuring the intracellular temperature by the temperature-sensitive probe are disclosed. The intracellular delivery vehicle is useful on account of its capability of easily delivering the component or compound desired inside the cell without inhibiting cell proliferation.Type: GrantFiled: September 6, 2016Date of Patent: July 14, 2020Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITYInventors: Toshikazu Tsuji, Kumiko Ikado, Sayuri Yamada, Seiichi Uchiyama, Kyoko Kawamoto, Hidetoshi Tokuyama, Kentaro Okano
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Publication number: 20190137503Abstract: An intracellular delivery vehicle of which surface is covered by a positive charge, an intracellular delivery complex in which a component or compound desired is loaded in the intracellular delivery vehicle, a temperature-sensitive probe comprising the intracellular delivery complex, and a method for measuring the intracellular temperature by the temperature-sensitive probe are disclosed. The intracellular delivery vehicle is useful on account of its capability of easily delivering the component or compound desired inside the cell without inhibiting cell proliferation.Type: ApplicationFiled: September 6, 2016Publication date: May 9, 2019Applicants: KIRIN KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYO, TOHOKU UNIVERSITYInventors: Toshikazu TSUJI, Kumiko IKADO, Sayuri YAMADA, Seiichi UCHIYAMA, Kyoko KAWAMOTO, Hidetoshi TOKUYAMA, Kentaro OKANO
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Publication number: 20190128874Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: ApplicationFiled: December 13, 2018Publication date: May 2, 2019Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
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Publication number: 20190113505Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: ApplicationFiled: December 13, 2018Publication date: April 18, 2019Applicants: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
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Patent number: 10191035Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: GrantFiled: May 20, 2014Date of Patent: January 29, 2019Assignees: KIRIN HOLDINGS KABUSHIKI KAISHA, THE UNIVERSITY OF TOKYOInventors: Toshikazu Tsuji, Kumiko Ikado, Seiichi Uchiyama, Kyoko Kawamoto
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Publication number: 20140342390Abstract: There is provided a method for introducing a temperature-sensitive probe comprising a copolymer, which comprises a thermoresponsive unit and a fluorescent unit, into a cell, and the method using the copolymer further comprising a cationic unit as the temperature-sensitive probe, and the method comprising the step of mixing the copolymer with the cell in a solvent. The copolymer can be preferably used as a fluorescence temperature sensor which measures intracellular temperature since the copolymer has a cationic group and thus enters into a cell without using a special method.Type: ApplicationFiled: May 20, 2014Publication date: November 20, 2014Applicants: THE UNIVERSITY OF TOKYO, KIRIN HOLDINGS KABUSHIKI KAISHAInventors: Toshikazu TSUJI, Kumiko IKADO, Seiichi UCHIYAMA, Kyoko KAWAMOTO
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Publication number: 20110196100Abstract: An object of the present invention is to provide a rubber composition for a tire, which is, when it is used as a rubber composition for a tire, capable of exhibiting good dry grip properties and excellent grip properties in both a relatively low temperature range and a relatively high temperature range, as well as a tire produced by using the rubber composition. The rubber composition of the present invention contains: a rubber component made of at least one type of diene-based polymer; and a copolymer resin obtained by copolymerizing ?-methylstyrene based monomer and aromatic vinyl monomer.Type: ApplicationFiled: February 16, 2009Publication date: August 11, 2011Applicant: BRIDGESTONE CORPORATIONInventors: Toshihiro Uchiyama, Seiichi Kato, Rika Fukushima
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Patent number: D293817Type: GrantFiled: July 23, 1986Date of Patent: January 19, 1988Assignee: Car Mate Manufacturing Company LimitedInventor: Seiichi Uchiyama
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Patent number: D309270Type: GrantFiled: October 9, 1987Date of Patent: July 17, 1990Assignee: Car Mate Manufacturing Company LimitedInventor: Seiichi Uchiyama