Abstract: A sliding resin composition is provided which hardly seizes by decreasing oil repellency of PTFE to prevent discharging of lubricating oil from sliding surface. That is, by using resin composition 1 where particles of PTFE 3 in the surface of which inorganic compound 4 having oil-absorptivity is embedded are dispersed in synthetic resin 2, the inorganic compound 4 having oil-absorptivity absorbs and retains lubricating oil, and oil repellency of PTFE 3 on the sliding surface can be decreased. Thus, discharging of the lubricating oil from the sliding surface can be inhibited and resin composition 1 hardly seizes.

Abstract: The present invention provides nonsteroidal tetrahydroquinoline derivatives of general formula (I) or salts thereof: (R1, R2, X, Y, Z and m are as defined in claim 1) which show no excessive action on the prostate but show a particularly potent androgen receptor agonistic action on skeletal muscle tissue and bone tissue, as well as pharmaceuticals comprising such derivatives or their salts as active ingredients.

Abstract: Tetrahydroquinoline compounds of general formula (I) or pharmacologically acceptable salts thereof, which have a specific and strong binding affinity for AR, exhibit AR agonism or antagonism, have therapeutic effects on AR-mediated diseases, particularly by not acting excessively on the prostate as AR agonists, but by showing potent action on skeletal muscle tissue and bone tissue; and pharmaceutical compositions comprising the compounds or the salts as active ingredients:

Abstract: Tetrahydroquinoline compounds of general formula (I) or pharmacologically acceptable salts thereof, which have a specific and strong binding affinity for AR, exhibit AR agonism or antagonism, have therapeutic effects on AR-mediated diseases, particularly by not acting excessively on the prostate as AR agonists, but by showing potent action on skeletal muscle tissue and bone tissue; and pharmaceutical compositions comprising the compounds or the salts as active ingredients: 1