Abstract: Provided is a method for producing effector cells expressing a desired specificity determining region. In this method, material cells that have a cassette deck structure with a cassette tape gene comprising a gene encoding a marker protein in their genome, wherein the material cells can be differentiated into the effector cells, and wherein the marker protein can be expressed in the effector cells or progenitor cells thereof when the material cells are differentiated into the effector cells or progenitor cells thereof are provided first. The material cells are proliferated, the proliferated cells are differentiated into the effector cells, and then, the gene encoding the marker protein in the effector cells is exchanged with a gene encoding a protein that contribute the desired specificity.

Abstract: To show an electromagnetic induction heating apparatus in which an object to be heated such as a half-finished light alloy wheel can be heated efficiently to have a predetermined temperature in a short time. An electromagnetic induction heating apparatus 1 includes a rotating body 2 with a plurality of magnets 21 arranged such that the same pole is positioned on the side of an object to be heated 8 and a rotation driving motor 3 for rotating the rotating body 2, in which the object to be heated 8 is heated by an induced current generated when the rotating body 2 is rotated. By controlling the distance D between the magnets 21 of the rotating body 2 and the object to be heated 8 with a moving motor 6, a light alloy wheel or the like, which has a high thermal expansion coefficient, can be well-heated efficiently.

Abstract: To show an electromagnetic induction heating apparatus in which an object to be heated such as a half-finished light alloy wheel can be heated efficiently to have a predetermined temperature in a short time. An electromagnetic induction heating apparatus 1 includes a rotating body 2 with a plurality of magnets 21 arranged such that the same pole is positioned on the side of an object to be heated 8 and a rotation driving motor 3 for rotating the rotating body 2, in which the object to be heated 8 is heated by an induced current generated when the rotating body 2 is rotated. By controlling the distance D between the magnets 21 of the rotating body 2 and the object to be heated 8 with a moving motor 6, a light alloy wheel or the like, which has a high thermal expansion coefficient, can be well-heated efficiently.

Abstract: The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.

Abstract: The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.

Abstract: An object of the present invention is to provide a transformation system for Labyrinthulomycota that allows the elucidation of biosynthetic mechanisms of lipids such as PUFA and carotenoids as well as for the construction of a high production system and the design and development of novel functional lipid molecules by the control of the mechanisms. The present invention provides a method for introducing a transgene into a cell of Labyrinthulomycota, which comprises introducing into a cell of Labyrinthulomycota a recombinant vector comprising a transgene and a nucleotide sequence which is homologous to a part of chromosomal DNA of Labyrinthulomycota and is capable of homologous recombination with the chromosomal DNA, and then inducing homologous recombination in this homologous nucleotide sequence.

Abstract: The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.

Abstract: An object of the present invention is to provide a transformation system for Labyrinthulomycota that allows the elucidation of biosynthetic mechanisms of lipids such as PUFA and carotenoids as well as for the construction of a high production system and the design and development of novel functional lipid molecules by the control of the mechanisms. The present invention provides a vector for the transformation of Labyrinthulomycota with a transgene, which comprises at least (1) a nucleotide sequence which is homologous to a part of chromosomal DNA of Labyrinthulomycota and is capable of homologous recombination with the chromosomal DNA, (2) a selection marker gene having a promoter sequence located upstream and a terminator sequence located downstream, and (3) a cloning site for transgene insertion having a promoter sequence located upstream and a terminator sequence located downstream.

Abstract: The present invention discloses anti-histone H1 monoclonal antibodies, hybridomas for the production thereof, and polypeptides, which are useful for suppressing, predicting, or diagnosing transplant rejection in organ transplantation.

Abstract: In a semiconductor laser device (LD1), a semiconductor laser layer is formed on one face of a semiconductor substrate (1), and a p-type electrode (8) and an n-type electrode (11) are provided on the semiconductor laser layer side and the semiconductor substrate (1) side, respectively, so as to sandwich the semiconductor laser layer and the semiconductor substrate (1) therebetween. The p-type electrode (8) includes a first electrode (9) and a second electrode (10) that covers the first electrode (9).

Abstract: A chain-driving mechanism and a conveyor apparatus of the present invention include a plurality of rollers (20) arranged to convey to-be-conveyed objects, a driving mechanism that drives the rollers (20) in conjunction with each other, and a motor (80) that exerts a driving force onto the driving mechanism. The driving mechanism includes a plurality of sprockets (40) that rotate coaxially with and together with the rollers (20), an endless chain (50) wound onto the sprockets (40), and a chain guide (60, 61, 62) disposed adjacent to the chain (50) so as to sandwich the chain (50) from the outside in the upward and downward directions. With this structure, there is no need to adjust the stretch of the chain, and the chain can be prevented from slipping off. Additionally, the structure can be made simpler, and costs can be made smaller.

Abstract: An object of the present invention is to provide a transformation system for Labyrinthulomycota that allows the elucidation of biosynthetic mechanisms of lipids such as PUFA and carotenoids as well as for the construction of a high production system and the design and development of novel functional lipid molecules by the control of the mechanisms. The present invention provides a vector for the transformation of Labyrinthulomycota with a transgene, which comprises at least (1) a nucleotide sequence which is homologous to a part of chromosomal DNA of Labyrinthulomycota and is capable of homologous recombination with the chromosomal DNA, (2) a selection marker gene having a promoter sequence located upstream and a terminator sequence located downstream, and (3) a cloning site for transgene insertion having a promoter sequence located upstream and a terminator sequence located downstream.

Abstract: An object of the present invention is to provide a transformation system for Labyrinthulomycota that allows the elucidation of biosynthetic mechanisms of lipids such as PUFA and carotenoids as well as for the construction of a high production system and the design and development of novel functional lipid molecules by the control of the mechanisms. The present invention provides a method for introducing a transgene into a cell of Labyrinthulomycota, which comprises introducing into a cell of Labyrinthulomycota a recombinant vector comprising a transgene and a nucleotide sequence which is homologous to a part of chromosomal DNA of Labyrinthulomycota and is capable of homologous recombination with the chromosomal DNA, and then inducing homologous recombination in this homologous nucleotide sequence.

Abstract: The chain-driving mechanism and the conveyor apparatus of the present invention include a plurality of rollers (20) arranged to convey to-be-conveyed objects, a driving mechanism that drives the rollers (20) in conjunction with each other, and a motor (80) that exerts a driving force onto the driving mechanism. The driving mechanism includes a plurality of sprockets (40) that rotate coaxially with and together with the rollers (20), an endless chain (50) wound onto the sprockets (40), and a chain guide (60, 61, 62) disposed adjacent to the chain (50) so as to sandwich the chain (50) from the outside in the upward and downward directions. With this structure, there is no need to adjust the stretch of the chain, and the chain can be prevented from slipping off. Additionally, the structure can be made simpler, and costs can be made smaller.

Abstract: There are provided immunosuppressants with few side effects that can be used to suppress rejection involving organ transplantation, and the immunosuppressants comprising antibodies against histone H1 which specifically recognize antigenic proteins may be used to suppress immunity in mammals for treatment or prevention of rejection involving organ transplantation.

Abstract: Novel inhibitors of IgE production which comprises at least one or more compound selected from the group consisting of &ggr;-linolenic acid, di-homo-&ggr;-linolenic acid and derivatives thereof as an active ingredient(s) are useful in treating skin conditions and the like in which IgG participate.

Abstract: Provided is an optical recording medium comprising at least a recording layer, a metal reflective layer, a protective layer and a printing layer laminated on a transparent substrate, wherein the printing layer is obtained by curing a UV-curing ink composition and said ink composition contains a compound which has a solubility parameter falling in the range of 7 to 10 and which takes no part in UV curing and does not react with other components contained therein.

Abstract: An aqueous emulsion comprising a copolymer having a two-layer structure is produced by polymerizing at least one aqueous vinyl monomer component (II) in the presence of a seed emulsion (I) comprising seeds composed of a copolymer containing 10-50% by weight of (meth)acrylonitrile as a monomer unit. This aqueous emulsion has heat resistance, solvent resistance, and anti-blocking property, and can be used as an undercoating agent, an agent for treating a back side, a binder for diazo photosensitive paper, a binder for an offset master, and the like.

Abstract: An insecticidal resin coating film comprising a combination of an acrylonitrile and/or methacrylonitrile copolymer resin and an insecticidal component selected from the group consisting of specified compounds exhibits an insecticidal effect, since the compound is kept on the surface of the coating film in a state capable of exhibiting its insecticidal effect for a long period of time.

Abstract: An insecticidal resin coating film comprising a combination of an acrylonitrile and/or methacrylonitrile copolymer resin and an insecticidal component selected from the group consisting of specified compounds exhibits an insecticidal effect, since the compound is kept on the surface of the coating film in a state capable of exhibiting its insecticidal effect for a long period of time.