Patents by Inventor Seiji Shibahara

Seiji Shibahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of antibiotic 1-oxadethiacephalosporins, and intermediate
    Patent number: 4556513
    Abstract: Disclosed is a process for preparing antibiotic 1-oxadethiacephalosporins via diazo-species I: ##STR1## wherein: A is acyl; R.sup.1 is H or OCH.sub.3 ; and R.sup.2 is a protecting group.
    Type: Grant
    Filed: August 15, 1984
    Date of Patent: December 3, 1985
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Seiji Shibahara, Tsuneo Okonogi, Yasushi Murai, Shunzo Fukatsu, Taro Niida, Tadashi Wakazawa
  • 1-Oxa-1-dethia-cephalosporin derivatives
    Patent number: 4534898
    Abstract: This invention relates to 1-oxa-1-dethia-cephalosporins which are useful as anti-biotics.
    Type: Grant
    Filed: July 20, 1983
    Date of Patent: August 13, 1985
    Assignee: Merck & Co., Inc.
    Inventors: Seiji Shibahara, Tsuneo Okonogi, Yasushi Murai, Shunzo Fukatsu, Tadashi Wakazawa, Taro Niida, Burton G. Christensen
  • 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same
    Patent number: 4497811
    Abstract: New 1-Oxadethiacephalosporins having a 3-loweralkyl thio group, and antibacterial compositions containing the same.
    Type: Grant
    Filed: July 1, 1983
    Date of Patent: February 5, 1985
    Inventors: Seiji Shibahara, Tsuneo Okonogi, Yasushi Murai, Shunzo Futkatsu, Taro Niida, Tadashi Wakazawa
  • Processes for the production of antibiotic 1-oxadethiacephalosporins
    Patent number: 4472576
    Abstract: Disclosed is a process for preparing antibiotic 1-oxadethiacephalosporins via diazo-species I: ##STR1## wherein: A is acyl; R.sup.1 is H or OCH.sub.3 ; and R.sup.2 is a protecting group.
    Type: Grant
    Filed: December 3, 1982
    Date of Patent: September 18, 1984
    Assignee: Merck & Co., Inc.
    Inventors: Tadashi Wakazawa, Taro Niida, Shunzo Fukatsu, Yasushi Murai, Tsuneo Okonogi, Seiji Shibahara
  • Process for the production of 4-aminobutyric acid or its derivatives
    Patent number: 4290972
    Abstract: 4-Amino-2-hydroxybutyric acid or 2,4-diaminobutyric acid may be readily produced by a new process comprising reacting a propionic acid compound containing a .beta.-carboxamido substituent (-CONH.sub.2) on the carbon atom at the 3-position and optionally containing hydroxyl substituent and protected or unprotected amino substituent on the .alpha.-carbon atom thereof, with an alkanoic acid anhydride in liquid pyridine to convert the carboxamido group into a nitrile group, with occasional acylation of a .alpha.-hydroxyl group, occasionally removing the alkanoyl group from the .alpha.-acyloxyl group of the resulting nitrile intermediate, and then reducing the resultant nitrile compound with hydrogen to convert the nitrile group into an aminomethyl group, and further optionally removing the residual amino-protecting group from the resultant 4-aminobutyric acid compound.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: September 22, 1981
    Assignee: Meiji Seika Kaisha, Ltd.
    Inventors: Toshio Yoneta, Seiji Shibahara, Shigeo Seki, Shunzo Fukatsu