Patents by Inventor Seikh Samad Hossain

Seikh Samad Hossain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Targeted drug delivery through affinity based linkers
    Patent number: 11701429
    Abstract: The current invention describes a conjugate of a targeting moiety linked to a drug via a molecule having high affinity for the targeting moiety at physiological pH such that the drug releases at low pH from the targeting moiety.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: July 18, 2023
    Assignee: AKAMARA THERAPEUTICS, INC.
    Inventors: Shiladitya Sengupta, Monideepa Roy, Nimish Gupta, Seikh Samad Hossain
  • TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS
    Publication number: 20200199249
    Abstract: The current invention describes a conjugate of a targeting moiety linked to a drug via a molecule having high affinity for the targeting moiety at physiological pH such that the drug releases at low pH from the targeting moiety.
    Type: Application
    Filed: January 7, 2020
    Publication date: June 25, 2020
    Applicant: AKAMARA THERAPEUTICS, INC.
    Inventors: Shiladitya SENGUPTA, Monideepa ROY, Nimish GUPTA, Seikh Samad HOSSAIN
  • Targeted drug delivery through affinity based linkers
    Patent number: 10533059
    Abstract: The current invention discloses targeted drug delivery conjugates comprising a targeting moiety linked to a drug via a molecule having an affinity for the targeting moiety. Typically, the conjugate comprises a targeting ligand and a molecule of interest, e.g., a therapeutic agent. The targeting ligand and the molecule of interest are linked to each other via an affinity ligand. The affinity ligand is further covalently or non-covalently linked to a drug or therapeutic agent. The drug can be modified to make it more soluble and so that it cleaves from the linking molecule at the target site.
    Type: Grant
    Filed: March 11, 2015
    Date of Patent: January 14, 2020
    Assignee: AKAMARA THERAPEUTICS, INC.
    Inventors: Shiladitya Sengupta, Monideepa Roy, Nimish Gupta, Seikh Samad Hossain
  • LIGAND-TARGETED MOLECULES AND METHODS THEREOF
    Publication number: 20180104353
    Abstract: The present invention relates to ligand-targeted molecules and ligand drug conjugates (LDCs) comprising a ligand connected to a functional group, which is connected to a linker, with in turn is bonded to a drug. The LDCs of the present invention also comprise platinum coordination complex wherein the platinum is connected to the linker through monocarboxylato and O—*Pt coordinate bonds. The present invention also relates to methods for preparing these ligand drug conjugates. The present invention further relates to methods for the treatment of tumours using the ligand drug conjugates of the present invention.
    Type: Application
    Filed: December 15, 2017
    Publication date: April 19, 2018
    Applicant: INVICTUS ONCOLOGY PVT. LTD.
    Inventors: Shiladitya SENGUPTA, Sazid HUSSAIN, Dipankar PRAMANIK, Monideepa ROY, Seikh Samad HOSSAIN
  • Ligand-targeted molecules and methods thereof
    Patent number: 9884123
    Abstract: The present invention relates to ligand-targeted molecules and ligand drug conjugates (LDCs) comprising a ligand connected to a functional group, which is connected to a linker, which in turn is bonded to a drug. The LDCs of the present invention also comprise platinum coordination complex wherein the platinum is connected to the linker through monocarboxylato and O?Pt coordinate bonds. The present invention also relates to methods for preparing these ligand drug conjugates. The present invention further relates to methods for the treatment of tumours using the ligand drug conjugates of the present invention.
    Type: Grant
    Filed: January 3, 2013
    Date of Patent: February 6, 2018
    Assignee: INVICTUS ONCOLOGY PVT. LTD.
    Inventors: Shiladitya Sengupta, Sazid Hussain, Dipankar Pramanik, Monideepa Roy, Seikh Samad Hossain
  • TARGETED DRUG DELIVERY THROUGH AFFINITY BASED LINKERS
    Publication number: 20170014528
    Abstract: The current invention discloses targeted drug delivery conjugates comprising a targeting moiety linked to a drug via a molecule having an affinity for the targeting moiety. Typically, the conjugate comprises a targeting ligand and a molecule of interest, e.g., a therapeutic agent. The targeting ligand and the molecule of interest are linked to each other via an affinity ligand. The affinity ligand is further covalently or non-covalently linked to a drug or therapeutic agent. The drug can be modified to make it more soluble and so that it cleaves from the linking molecule at the target site.
    Type: Application
    Filed: March 11, 2015
    Publication date: January 19, 2017
    Applicant: INVICTUS ONCOLOGY PVT. LTD.
    Inventors: Shiladitya SENGUPTA, Monideepa ROY, Nimish GUPTA, Seikh Samad HOSSAIN
  • LIGAND-TARGETED MOLECULES AND METHODS THEREOF
    Publication number: 20150045428
    Abstract: The present invention relates to ligand-targeted molecules and ligand drug conjugates (LDCs) comprising a ligand connected to a functional group, which is connected to a linker, which in turn is bonded to a drug. The LDCs of the present invention also comprise platinum coordination complex wherein the platinum is connected to the linker through monocarboxylato and O?Pt coordinate bonds. The present invention also relates to methods for preparing these ligand drug conjugates. The present invention further relates to methods for the treatment of tumours using the ligand drug conjugates of the present invention.
    Type: Application
    Filed: January 3, 2013
    Publication date: February 12, 2015
    Inventors: Shiladitya Sengupta, Sazid Hussain, Dipankar Pramanik, Monideepa Roy, Seikh Samad Hossain