Patents by Inventor Seima Itami

Seima Itami has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral Agent
    Publication number: 20090028820
    Abstract: An antiviral agent consisting of hepatocyte growth factor (HGF) or an agonist of the HGF receptor, and a medicament for prophylactic and/or therapeutic treatment of a disease caused by hepatitis C virus comprising using said agent simultaneously or separately with other anti-viral agent.
    Type: Application
    Filed: March 2, 2006
    Publication date: January 29, 2009
    Inventors: Takehisa Ishii, Seima Itami
  • Monoclonal antibody and gene encoding the same, hybridoma, pharmaceutical composition, and diagnostic reagent
    Patent number: 7396915
    Abstract: A novel human monoclonal antibody specifically recognizing cancer cells such as non-small cell lung cancer, pancreatic cancer and gastric cancer cells is produced by hybridomas which are obtained by fusing lymphocytes derived from a cancer tissue of a cancer patient with mouse myeloma cells. An anti-cancer drug is obtained by using the antibody alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein. More specifically, an anti-cancer drug is obtained by using an antibody, in which variable region of its heavy chain comprises the amino acid sequence of SEQ ID NO: 115 and variable region of the light chain comprises the amino acid sequence of SEQ ID NO: 117, alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: July 8, 2008
    Assignees: Mitsubishi Pharma Corporation, Keio University
    Inventors: Saiko Hosokawa, Masahiko Aoki, Yoko Hirakawa, Seima Itami, Hiroe Umeki, Yoshiro Saikawa, Koichiro Kumai, Kazumasa Fukuda
  • Remedies for hepatitis C
    Patent number: 7101551
    Abstract: The present invention provides a substance which inhibits the binding between E2/NS1 protein of hepatitis C virus and a cell infectious with hepatitis C virus, a cell expressing CD81, or CD81. The present invention can provide a novel medicament which has an anti-viral effects such as an inhibitory action against HCV infection.
    Type: Grant
    Filed: February 13, 2001
    Date of Patent: September 5, 2006
    Assignees: Mitsubishi Pharma Corporation, Japan as Represented by Director General of Agency of National Institute of Infectious Diseases
    Inventors: Seima Itami, Tatsurou Shibui, Makoto Seki, Yoshihisa Yotsumoto, Yoshiharu Matsuura, Tatsuo Miyamura
  • Monoclonal antibody and gene encoding the same, hybridoma, pharmaceutical composition, and diagnostic reagent
    Publication number: 20060088538
    Abstract: A novel human monoclonal antibody specifically recognizing cancer cells such as non-small cell lung cancer, pancreatic cancer and gastric cancer cells is produced by hybridomas which are obtained by fusing lymphocytes derived from a cancer tissue of a cancer patient with mouse myeloma cells. An anti-cancer drug is obtained by using the antibody alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein. More specifically, an anti-cancer drug is obtained by using an antibody, in which variable region of its heavy chain comprises the amino acid sequence of SEQ ID NO: 115 and variable region of the light chain comprises the amino acid sequence of SEQ ID NO: 117, alone or anchoring the antibody on the surface of a liposome containing a toxin or an anti-cancer drug encapsulated therein.
    Type: Application
    Filed: February 27, 2004
    Publication date: April 27, 2006
    Applicants: Mitsubishi Pharma Corporation, Keio University
    Inventors: Saiko Hosokawa, Masahiko Aoki, Yoko Hirakawa, Seima Itami, Hiroe Umeki, Yoshiro Saikawa, Koichiro Kumai, Kazumasa Fukuda
  • Expression vector enabling screening of cells with high expression of recombinant protein, transformant with high expression of recombinant protein and utilization thereof
    Publication number: 20040038392
    Abstract: The present invention relates to an expression vector which comprises an expression unit containing a first selective marker gene and an expression unit containing a second selective marker gene which differs from the first selective marker gene; a transformant having the expression vector; a method for screening cells which express high level of a recombinant protein by use of the transformant; and the like.
    Type: Application
    Filed: July 21, 2003
    Publication date: February 26, 2004
    Inventors: Tatsurou Shibui, Yasufumi Fukano, Masahiro Kitou, Seima Itami
  • Remedies for hepatitis c
    Publication number: 20030157132
    Abstract: The present invention provides a substance which inhibits the binding between E2/NS1 protein of hepatitis C virus and a cell infectious with hepatitis C virus, a cell expressing CD81, or CD81. The present invention can provide a novel medicament which has an anti-viral effects such as an inhibitory action against HCV infection.
    Type: Application
    Filed: November 26, 2002
    Publication date: August 21, 2003
    Inventors: Seima Itami, Tatsurou Shibui, Makoto Seki, Yoshihisa Yotsumoto, Yoshiharu Matsuura, Tatsuo Miyamura